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A Phase 1/2 trial of SRA737 (a Chk1 inhibitor) administered orally in patients with advanced cancer.
Kristeleit, Rebecca; Plummer, Ruth; Jones, Robert; Carter, Louise; Blagden, Sarah; Sarker, Debashis; Arkenau, Tobias; Evans, Thomas R Jeffry; Danson, Sarah; Symeonides, Stefan N; Veal, Gareth J; Klencke, Barbara J; Kowalski, Mark M; Banerji, Udai.
Afiliação
  • Kristeleit R; Guy's and St Thomas' NHS Foundation Trust, London, UK.
  • Plummer R; Newcastle University and Newcastle Hospitals NHS Trust, Newcastle Upon Tyne, UK.
  • Jones R; Velindre School of Medicine, Cardiff University, and Velindre University NHS Trust, Cardiff, UK.
  • Carter L; Division of Cancer Sciences, The University of Manchester and The Christie NHS Foundation Trust, Manchester, UK.
  • Blagden S; Early Phase Clinical Trials Unit, Churchill Hospital, Oxford University Hospital NHS Trust, Oxford, UK.
  • Sarker D; King's College London and Guy's Hospital, London, UK.
  • Arkenau T; Sarah Cannon Research Institute, London, UK.
  • Evans TRJ; The Beatson West of Scotland Cancer Centre and the University of Glasgow, Glasgow, UK.
  • Danson S; Sheffield ECMC, Department of Oncology and Metabolism, University of Sheffield, and Sheffield Teaching Hospital NHS Foundation Trust, Sheffield, UK.
  • Symeonides SN; Edinburgh ECMC, Institute of Genetics & Cancer, University of Edinburgh, Edinburgh Cancer Centre, Edinburgh, UK.
  • Veal GJ; Newcastle University Centre for Cancer, Translational and Clinical Research Institute, Newcastle upon Tyne, UK.
  • Klencke BJ; Sierra Oncology Inc., San Mateo, CA, USA.
  • Kowalski MM; Sierra Oncology Inc., San Mateo, CA, USA.
  • Banerji U; The Institute of Cancer Research and The Royal Marsden Hospital NHS Foundation Trust, London, UK. udai.banerji@icr.ac.uk.
Br J Cancer ; 129(1): 38-45, 2023 07.
Article em En | MEDLINE | ID: mdl-37120671
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Idioma: En Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Reino Unido
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Idioma: En Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Reino Unido