A proof-of-concept pipeline to guide evaluation of tumor tissue perfusion by dynamic contrast-agent imaging: Direct simulation and inverse tracer-kinetic procedures.

Vignon-Clementel, Irene E; Jagiella, Nick; Dichamp, Jules; Kowalski, Jérôme; Lederle, Wiltrud; Laue, Hendrik; Kiessling, Fabian; Sedlaczek, Oliver; Drasdo, Dirk

Vignon-Clementel, Irene E; Jagiella, Nick; Dichamp, Jules; Kowalski, Jérôme; Lederle, Wiltrud; Laue, Hendrik; Kiessling, Fabian; Sedlaczek, Oliver; Drasdo, Dirk.

Afiliação

Vignon-Clementel IE; Inria, Palaiseau, France.
Jagiella N; Inria, Palaiseau, France.
Dichamp J; Inria, Palaiseau, France.
Kowalski J; Inria, Palaiseau, France.
Lederle W; Institute for Experimental Molecular Imaging (ExMI), University Clinic and Helmholtz Institute for Biomedical Engineering, RWTH Aachen University, Aachen, Germany.
Laue H; Fraunhofer MEVIS, Institute for Digital Medicine, Bremen, Germany.
Kiessling F; Institute for Experimental Molecular Imaging (ExMI), University Clinic and Helmholtz Institute for Biomedical Engineering, RWTH Aachen University, Aachen, Germany.
Sedlaczek O; Fraunhofer MEVIS, Institute for Digital Medicine, Aachen, Germany.
Drasdo D; Department of NCT Radiology Uniklinikum/DKFZ Heidelberg, Heidelberg, Germany.

Front Bioinform ; 3: 977228, 2023.

Article em En | MEDLINE | ID: mdl-37122998

Palavras-chave

dynamic contrast-enhanced imaging; in silico imaging; microcirculation; parameter estimation; tracer-kinetics models; tumor perfusion

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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2023 Tipo de documento: Article País de afiliação: França

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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2023 Tipo de documento: Article País de afiliação: França