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Genetic studies of paired metabolomes reveal enzymatic and transport processes at the interface of plasma and urine.
Schlosser, Pascal; Scherer, Nora; Grundner-Culemann, Franziska; Monteiro-Martins, Sara; Haug, Stefan; Steinbrenner, Inga; Uluvar, Burulça; Wuttke, Matthias; Cheng, Yurong; Ekici, Arif B; Gyimesi, Gergely; Karoly, Edward D; Kotsis, Fruzsina; Mielke, Johanna; Gomez, Maria F; Yu, Bing; Grams, Morgan E; Coresh, Josef; Boerwinkle, Eric; Köttgen, Michael; Kronenberg, Florian; Meiselbach, Heike; Mohney, Robert P; Akilesh, Shreeram; Schmidts, Miriam; Hediger, Matthias A; Schultheiss, Ulla T; Eckardt, Kai-Uwe; Oefner, Peter J; Sekula, Peggy; Li, Yong; Köttgen, Anna.
Afiliação
  • Schlosser P; Institute of Genetic Epidemiology, Faculty of Medicine and Medical Center - University of Freiburg, Freiburg, Germany. pascal.schlosser@uniklinik-freiburg.de.
  • Scherer N; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA. pascal.schlosser@uniklinik-freiburg.de.
  • Grundner-Culemann F; Institute of Genetic Epidemiology, Faculty of Medicine and Medical Center - University of Freiburg, Freiburg, Germany.
  • Monteiro-Martins S; Spemann Graduate School of Biology and Medicine, University of Freiburg, Freiburg, Germany.
  • Haug S; Institute of Genetic Epidemiology, Faculty of Medicine and Medical Center - University of Freiburg, Freiburg, Germany.
  • Steinbrenner I; Institute of Genetic Epidemiology, Faculty of Medicine and Medical Center - University of Freiburg, Freiburg, Germany.
  • Uluvar B; Institute of Genetic Epidemiology, Faculty of Medicine and Medical Center - University of Freiburg, Freiburg, Germany.
  • Wuttke M; Institute of Genetic Epidemiology, Faculty of Medicine and Medical Center - University of Freiburg, Freiburg, Germany.
  • Cheng Y; Institute of Genetic Epidemiology, Faculty of Medicine and Medical Center - University of Freiburg, Freiburg, Germany.
  • Ekici AB; Institute of Genetic Epidemiology, Faculty of Medicine and Medical Center - University of Freiburg, Freiburg, Germany.
  • Gyimesi G; Institute of Genetic Epidemiology, Faculty of Medicine and Medical Center - University of Freiburg, Freiburg, Germany.
  • Karoly ED; Institute of Human Genetics, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
  • Kotsis F; Membrane Transport Discovery Lab, Department of Nephrology and Hypertension and Department of Biomedical Research, University of Bern, Bern, Switzerland.
  • Mielke J; Metabolon, Inc., Morrisville, NC, USA.
  • Gomez MF; Institute of Genetic Epidemiology, Faculty of Medicine and Medical Center - University of Freiburg, Freiburg, Germany.
  • Yu B; Department of Medicine IV-Nephrology and Primary Care, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, Germany.
  • Grams ME; Research and Early Development, Pharmaceuticals Division, Bayer AG, Wuppertal, Germany.
  • Coresh J; Department of Clinical Sciences in Malmö, Lund University Diabetes Centre, Lund University, Lund, Sweden.
  • Boerwinkle E; Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, USA.
  • Köttgen M; New York University Grossman School of Medicine, New York, NY, USA.
  • Kronenberg F; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
  • Meiselbach H; Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, USA.
  • Mohney RP; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA.
  • Akilesh S; Department of Medicine IV-Nephrology and Primary Care, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, Germany.
  • Schmidts M; Institute of Genetic Epidemiology, Department of Genetics, Medical University of Innsbruck, Innsbruck, Austria.
  • Hediger MA; Department of Nephrology and Hypertension, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
  • Schultheiss UT; Metabolon, Inc., Morrisville, NC, USA.
  • Eckardt KU; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, USA.
  • Sekula P; Centre for Integrative Biological Signalling Studies (CIBSS), Albert-Ludwigs-University Freiburg, Freiburg, Germany.
  • Li Y; Freiburg University Faculty of Medicine, Center for Pediatrics and Adolescent Medicine, University Hospital Freiburg, Freiburg, Germany.
  • Köttgen A; Membrane Transport Discovery Lab, Department of Nephrology and Hypertension and Department of Biomedical Research, University of Bern, Bern, Switzerland.
Nat Genet ; 55(6): 995-1008, 2023 06.
Article em En | MEDLINE | ID: mdl-37277652
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Metaboloma / Rim Idioma: En Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Alemanha
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Metaboloma / Rim Idioma: En Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Alemanha