Lu AF35700 reverses the phencyclidine-induced disruption of thalamo-cortical activity by blocking dopamine D<sub>1</sub> and D<sub>2</sub> receptors.

Riga, Maurizio S; Paz, Veronica; Didriksen, Michael; Celada, Pau; Artigas, Francesc

Lu AF35700 reverses the phencyclidine-induced disruption of thalamo-cortical activity by blocking dopamine D₁ and D₂ receptors.

Riga, Maurizio S; Paz, Veronica; Didriksen, Michael; Celada, Pau; Artigas, Francesc.

Afiliação

Riga MS; Department of Neuroscience and Experimental Therapeutics, CSIC-Institut d'Investigacions Biomèdiques de Barcelona, Barcelona, Spain; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain; Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Instituto de
Paz V; Department of Neuroscience and Experimental Therapeutics, CSIC-Institut d'Investigacions Biomèdiques de Barcelona, Barcelona, Spain; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain; Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Instituto de
Didriksen M; H. Lundbeck A/S, Synaptic Transmission, Neuroscience Research DK, Valby, Denmark.
Celada P; Department of Neuroscience and Experimental Therapeutics, CSIC-Institut d'Investigacions Biomèdiques de Barcelona, Barcelona, Spain; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain; Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Instituto de
Artigas F; Department of Neuroscience and Experimental Therapeutics, CSIC-Institut d'Investigacions Biomèdiques de Barcelona, Barcelona, Spain; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain; Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Instituto de

Eur J Pharmacol ; 953: 175802, 2023 Aug 15.

Article em En | MEDLINE | ID: mdl-37295763

Assuntos

Antipsicóticos; Clozapina; Ratos; Animais; Fenciclidina/farmacologia; Clozapina/farmacologia; Haloperidol/farmacologia; Dopamina; Antipsicóticos/farmacologia; Antagonistas de Dopamina/farmacologia; Receptores de Dopamina D1

Palavras-chave

D(1) receptor; D(2) receptor; Phencyclidine; Thalamo-cortical activity; cfos

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Antipsicóticos / Clozapina Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Antipsicóticos / Clozapina Idioma: En Ano de publicação: 2023 Tipo de documento: Article