Three-Dimensional Neodymium Metal-Organic Framework for Catalyzing the Cyanosilylation of Aldehyde and the Synthesis of 2,3-Dihydroquinazolin-4(1H)-one Derivatives.

In this work, a novel 3D lanthanide metal-organic framework (Ln-MOF) Nd-cdip (H4cdip = 5,5'-carbonyldiisophthalic acid) was successfully synthesized, which could be used as an efficient heterogeneous catalyst for cyanosilylation and the synthesis of 2,3-dihydroquinazolin-4(1H)-one derivatives at room temperature based on the Lewis acid sites in the channels of the MOF. Moreover, Nd-cdip had an excellent turnover number (500) for catalyzing cyanosilylation in no solvent condition. Nd-cdip could be reused in both of the above-mentioned reactions at least five times without a significant decrease in yield. The possible mechanism of cyanosilylation catalyzed by Nd-cdip was studied by using the luminescence properties of Tb-cdip, which has the same structure and functions as Nd-cdip. Furthermore, both reactions catalyzed by Nd-cdip were fitted to zero-order dynamics.