Discovery of VH domains that allosterically inhibit ENPP1.

Solomon, Paige E; Bracken, Colton J; Carozza, Jacqueline A; Wang, Haoqing; Young, Elizabeth P; Wellner, Alon; Liu, Chang C; Sweet-Cordero, E Alejandro; Li, Lingyin; Wells, James A

Solomon, Paige E; Bracken, Colton J; Carozza, Jacqueline A; Wang, Haoqing; Young, Elizabeth P; Wellner, Alon; Liu, Chang C; Sweet-Cordero, E Alejandro; Li, Lingyin; Wells, James A.

Afiliação

Solomon PE; Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, CA, USA.
Bracken CJ; Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, CA, USA.
Carozza JA; Cartography Biosciences, South San Francisco, CA, USA.
Wang H; Department of Biochemistry, Stanford University Medical School, Stanford, CA, USA.
Young EP; Sarafan ChEM-H, Stanford University, Stanford, CA, USA.
Wellner A; Macromolecular Structural Knowledge Center, Stanford University, Stanford, CA, USA.
Liu CC; Division of Pediatric Oncology, Department of Pediatrics, University of California San Francisco, San Francisco, CA, USA.
Sweet-Cordero EA; Department of Biomedical Engineering, University of California, Irvine, CA, USA.
Li L; Department of Biomedical Engineering, University of California, Irvine, CA, USA.
Wells JA; Department of Chemistry, University of California, Irvine, CA, USA.

Nat Chem Biol ; 20(1): 30-41, 2024 Jan.

Article em En | MEDLINE | ID: mdl-37400538

Assuntos

Diester Fosfórico Hidrolases; Anticorpos de Domínio Único; Diester Fosfórico Hidrolases/metabolismo; Monoéster Fosfórico Hidrolases; Microscopia Crioeletrônica

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Diester Fosfórico Hidrolases / Anticorpos de Domínio Único Idioma: En Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Estados Unidos

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