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Discovery of blood-brain barrier permeable and orally bioavailable caffeine-based amide derivatives as acetylcholinesterase inhibitors.
Sharma, Mohit; Sharma, Ankita; Thakur, Shikha; Nuthakki, Vijay K; Jamwal, Ashiya; Nandi, Utpal; Jadhav, Hemant R; Bharate, Sandip B.
Afiliação
  • Sharma M; Natural Products and Medicinal Chemistry Division, CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu 180001, India; Academy of Scientific & Innovative Research, Ghaziabad 201002, India.
  • Sharma A; Natural Products and Medicinal Chemistry Division, CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu 180001, India; Academy of Scientific & Innovative Research, Ghaziabad 201002, India.
  • Thakur S; Department of Pharmacy, Birla Institute of Technology and Sciences Pilani, Pilani Campus, Vidya Vihar, Pilani 333031, Rajasthan, India.
  • Nuthakki VK; Natural Products and Medicinal Chemistry Division, CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu 180001, India; Academy of Scientific & Innovative Research, Ghaziabad 201002, India.
  • Jamwal A; Academy of Scientific & Innovative Research, Ghaziabad 201002, India; Pharmacology Division, CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu 180001, India.
  • Nandi U; Academy of Scientific & Innovative Research, Ghaziabad 201002, India; Pharmacology Division, CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu 180001, India.
  • Jadhav HR; Department of Pharmacy, Birla Institute of Technology and Sciences Pilani, Pilani Campus, Vidya Vihar, Pilani 333031, Rajasthan, India.
  • Bharate SB; Natural Products and Medicinal Chemistry Division, CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu 180001, India; Academy of Scientific & Innovative Research, Ghaziabad 201002, India; Department of Natural Products and Medicinal Chemistry, CSIR-Indian Institute of Chemical Techn
Bioorg Chem ; 139: 106719, 2023 10.
Article em En | MEDLINE | ID: mdl-37473478
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inibidores da Colinesterase / Doença de Alzheimer Idioma: En Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Índia
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inibidores da Colinesterase / Doença de Alzheimer Idioma: En Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Índia