Uniformly shaped harmonization combines human transcriptomic data from different platforms while retaining their biological properties and differential gene expression patterns.

Borisov, Nicolas; Tkachev, Victor; Simonov, Alexander; Sorokin, Maxim; Kim, Ella; Kuzmin, Denis; Karademir-Yilmaz, Betul; Buzdin, Anton

Borisov, Nicolas; Tkachev, Victor; Simonov, Alexander; Sorokin, Maxim; Kim, Ella; Kuzmin, Denis; Karademir-Yilmaz, Betul; Buzdin, Anton.

Afiliação

Borisov N; Omicsway Corp, Walnut, CA, United States.
Tkachev V; Moscow Institute of Physics and Technology, Dolgoprudny, Russia.
Simonov A; Oncobox Ltd., Moscow, Russia.
Sorokin M; Moscow Institute of Physics and Technology, Dolgoprudny, Russia.
Kim E; Oncobox Ltd., Moscow, Russia.
Kuzmin D; Moscow Institute of Physics and Technology, Dolgoprudny, Russia.
Karademir-Yilmaz B; Oncobox Ltd., Moscow, Russia.
Buzdin A; World-Class Research Center "Digital Biodesign and Personalized Healthcare", Sechenov First Moscow State Medical University, Moscow, Russia.

Front Mol Biosci ; 10: 1237129, 2023.

Article em En | MEDLINE | ID: mdl-37745690

Palavras-chave

RNA sequencing; cancer transcriptomics; correlation analysis; data normalization and harmonization; gene expression; microarray hybridization; platform bias; transcriptional profiles

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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo

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PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos