Molecular and network disruptions in neurodevelopment uncovered by single cell transcriptomics analysis of <i>CHD8</i> heterozygous cerebral organoids.

Astorkia, Maider; Liu, Yang; Pedrosa, Erika M; Lachman, Herbert M; Zheng, Deyou

Molecular and network disruptions in neurodevelopment uncovered by single cell transcriptomics analysis of CHD8 heterozygous cerebral organoids.

Astorkia, Maider; Liu, Yang; Pedrosa, Erika M; Lachman, Herbert M; Zheng, Deyou.

Afiliação

Astorkia M; Department of Genetics, Albert Einstein College of Medicine, Bronx, NY, USA.
Liu Y; Department of Genetics, Albert Einstein College of Medicine, Bronx, NY, USA.
Pedrosa EM; Department of Psychiatry and Behavioral Science, Albert Einstein College of Medicine, Bronx, NY, USA.
Lachman HM; Department of Genetics, Albert Einstein College of Medicine, Bronx, NY, USA.
Zheng D; Department of Psychiatry and Behavioral Science, Albert Einstein College of Medicine, Bronx, NY, USA.

bioRxiv ; 2023 Sep 27.

Article em En | MEDLINE | ID: mdl-37808768

Palavras-chave

ASD; Autism; CHD8; cell-cell communication; cerebral organoid; scRNA-seq

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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo

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PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos