mSphere of Influence: Hooray for HaloTag! A novel tool to study autophagy in mammalian cells.
mSphere
; 8(6): e0048223, 2023 Dec 20.
Article
em En
| MEDLINE
| ID: mdl-37905922
ABSTRACT
Laura Cheney works at the crossroads of HIV and autophagy, a critical biological process for cellular homeostasis, to understand more completely the pathogenesis of HIV-associated neurocognitive impairment. In this mSphere of Influence article, she reflects on how "A pulse-chasable reporter processing assay for mammalian autophagic flux with HaloTag" by Willa Wen-You Yim, Hayashi Yamamoto, and Noboru Mizushima (eLife 11e78923, 2022, https//doi.org/10.7554/eLife.78923) expands the tools for studying autophagy and inspired her to use this technology to develop a reporter to study autophagy of mitochondria, termed mitophagy, to further her own research goals.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Autofagia
/
Infecções por HIV
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article
País de afiliação:
Estados Unidos