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Lipoprotein (a) as a predictor of diabetic retinopathy in patients with type 2 diabetes: A systematic review.
Gholami Chahkand, Mohammad Sadra; Esmaeilpour Moallem, Fatemeh; Qezelgachi, Abolfazl; Seifouri, Kiana; Pesaran Afsharian, Armin; Sheikhzadeh, Farzad; Poursalehi, Atefe; Fani Sadrabadi, Fateme Sadat; Saghab Torbati, Mehrnush; Ramezanzade, Mohaddese; Alishiri, Goharsharieh; Ansari, Arina; Zare Dehabadi, Emad; Karimi Matloub, Saeed; Sheikh, Zahra; Deravi, Niloofar; Mehrtabar, Saba; Chichagi, Fatemeh; Faal Hamedanchi, Neda; Arzaghi, Mohammadreza; Asadi, Mahla; Alsadat Dadkhah, Parisa; Ansari, Akram.
Afiliação
  • Gholami Chahkand MS; Student Research Committee, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran.
  • Esmaeilpour Moallem F; Student Research Committee, Golestan University of Medical Sciences, Gorgan, Iran.
  • Qezelgachi A; Student Research Committee, Qazvin University of Medical Sciences, Qazvin, Iran.
  • Seifouri K; Student Research Committee, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Pesaran Afsharian A; Student Research Committee, Urmia University of Medical Sciences, Urmia, Iran.
  • Sheikhzadeh F; Student Research Committee, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
  • Poursalehi A; Student Research Committee, School of Paramedical, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Fani Sadrabadi FS; Student Research Committee, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
  • Saghab Torbati M; Islamic Azad University of Zahedan, Zahedan, Iran.
  • Ramezanzade M; School of Medicine, Guilan University of Medical Sciences, Rasht, Iran.
  • Alishiri G; Students Research Committee, School of Medicine, Ardabil University of Medical Sciences, Ardabil, Iran.
  • Ansari A; Student Research Committee, School of Medicine, North Khorasan University of Medical Sciences, Bojnurd, Iran.
  • Zare Dehabadi E; Student Research Committee, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Karimi Matloub S; Students Research Committee, Qom University of Medical Sciences, Qom, Iran.
  • Sheikh Z; Student Research Committee, School of Medicine, Babol University of Medical Sciences, Babol, Iran.
  • Deravi N; Student Research Committee, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Mehrtabar S; Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran.
  • Chichagi F; Students' Scientific Research Center (SSRC), Tehran University of Medical Sciences, Tehran, Iran.
  • Faal Hamedanchi N; Faculty of Medicine, Islamic Azad University, Tehran Medical Sciences Branch, Tehran, Iran.
  • Arzaghi M; Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Asadi M; Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
  • Alsadat Dadkhah P; Student Research Committee, Qazvin University of Medical Sciences, Qazvin, Iran.
  • Ansari A; Medical College, Shantou University, Shantou, China.
Diab Vasc Dis Res ; 20(6): 14791641231197114, 2023.
Article em En | MEDLINE | ID: mdl-38018132
BACKGROUND: Lipoprotein a (LP(a)), an LDL-like lipoprotein, known as a risk factor for cardiovascular diseases, has a controversial association with diabetic retinopathy in patients with type 2 diabetes-the current systematic review aimed to critically assess the association between LP(a) and diabetic retinopathy. METHODS: A systematic review of relevant studies was conducted after a thorough search in PubMed, Scopus, and Google Scholar electronic databases. We used English observational, case-control, and prospective cohort studies published up to August 2022, including type 2 diabetic patients as the population, diabetic retinopathy as the outcome, and LP(a) as the intervention. RESULT: 17 relevant studies, including 4688 patients with diabetes, were included in this systematic review. While in 13 studies, Lipoprotein(a) was recognized as a risk factor for diabetic retinopathy, only three studies reported no evidence of a relationship between the two. Also, another study showed a mixed outcome of the relationship between LP(a) and diabetic retinopathy. CONCLUSION: High serum lipoprotein(a) in patients with type 2 diabetes is considered a risk factor for diabetic retinopathy. However, further large-scaled cohort studies are still required to validate this finding.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Diabetes Mellitus Tipo 2 / Retinopatia Diabética Idioma: En Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Irã
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Diabetes Mellitus Tipo 2 / Retinopatia Diabética Idioma: En Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Irã