Suppression of circular RNA serum and glucocorticoid-induced kinase 1 elevates antioxidant molecules and angiogenesis in trophoblast cells to attenuate preeclampsia via microRNA-508-3p to target and restrain PUM homolog 1.

Lu, CaiXia; Zheng, FuMin; Pan, LiXiao; Han, QingFang; Wu, JiXia; Zhang, WenKe

Lu, CaiXia; Zheng, FuMin; Pan, LiXiao; Han, QingFang; Wu, JiXia; Zhang, WenKe.

Afiliação

Lu C; Department of Obstetrics, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
Zheng F; Department of Obstetrics, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
Pan L; Department of Anesthesiology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
Han Q; Department of Obstetrics, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
Wu J; Department of Obstetrics, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
Zhang W; Department of Obstetrics, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.

J Obstet Gynaecol Res ; 50(3): 322-333, 2024 Mar.

Article em En | MEDLINE | ID: mdl-38081797

Assuntos

MicroRNAs; Pré-Eclâmpsia; Humanos; Feminino; Gravidez; Ratos; Animais; Placenta/metabolismo; RNA Circular/genética; Antioxidantes/farmacologia; Antioxidantes/metabolismo; Glucocorticoides/metabolismo; MicroRNAs/genética; Pré-Eclâmpsia/tratamento farmacológico; Pré-Eclâmpsia/genética; Pré-Eclâmpsia/metabolismo; Angiogênese; Fator A de Crescimento do Endotélio Vascular/metabolismo; Trofoblastos/metabolismo; Proteínas de Ligação a RNA/metabolismo

Palavras-chave

PUM homolog 1; circular RNA serum and glucocorticoid-induced kinase 1; microRNA-508-3p; preeclampsia

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pré-Eclâmpsia / MicroRNAs Idioma: En Ano de publicação: 2024 Tipo de documento: Article País de afiliação: China

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