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SARS-CoV-2 in Animal Companions: A Serosurvey in Three Regions of Southern Italy.
Bianco, Angelica; Bortolami, Alessio; Miccolupo, Angela; Sottili, Roldano; Ghergo, Paola; Castellana, Stefano; Del Sambro, Laura; Capozzi, Loredana; Pagliari, Matteo; Bonfante, Francesco; Ridolfi, Donato; Bulzacchelli, Carmela; Giannico, Anna; Parisi, Antonio.
Afiliação
  • Bianco A; Istituto Zooprofilattico Sperimentale della Puglia e Basilicata, Via Manfredonia n. 20, 71121 Foggia, Italy.
  • Bortolami A; Department of Comparative Biomedical Sciences, Istituto Zooprofilattico Sperimentale delle Venezie, Viale dell'Università 10, 35020 Legnaro, Italy.
  • Miccolupo A; Istituto Zooprofilattico Sperimentale della Puglia e Basilicata, Via Manfredonia n. 20, 71121 Foggia, Italy.
  • Sottili R; ACV Triggiano Laboratorio di Analisi Cliniche Veterinarie, Via Suor Marcella Arosio 8, 70019 Triggiano, Italy.
  • Ghergo P; ACV Triggiano Laboratorio di Analisi Cliniche Veterinarie, Via Suor Marcella Arosio 8, 70019 Triggiano, Italy.
  • Castellana S; Istituto Zooprofilattico Sperimentale della Puglia e Basilicata, Via Manfredonia n. 20, 71121 Foggia, Italy.
  • Del Sambro L; Istituto Zooprofilattico Sperimentale della Puglia e Basilicata, Via Manfredonia n. 20, 71121 Foggia, Italy.
  • Capozzi L; Istituto Zooprofilattico Sperimentale della Puglia e Basilicata, Via Manfredonia n. 20, 71121 Foggia, Italy.
  • Pagliari M; Department of Comparative Biomedical Sciences, Istituto Zooprofilattico Sperimentale delle Venezie, Viale dell'Università 10, 35020 Legnaro, Italy.
  • Bonfante F; Department of Comparative Biomedical Sciences, Istituto Zooprofilattico Sperimentale delle Venezie, Viale dell'Università 10, 35020 Legnaro, Italy.
  • Ridolfi D; Istituto Zooprofilattico Sperimentale della Puglia e Basilicata, Via Manfredonia n. 20, 71121 Foggia, Italy.
  • Bulzacchelli C; Istituto Zooprofilattico Sperimentale della Puglia e Basilicata, Via Manfredonia n. 20, 71121 Foggia, Italy.
  • Giannico A; Istituto Zooprofilattico Sperimentale della Puglia e Basilicata, Via Manfredonia n. 20, 71121 Foggia, Italy.
  • Parisi A; Istituto Zooprofilattico Sperimentale della Puglia e Basilicata, Via Manfredonia n. 20, 71121 Foggia, Italy.
Life (Basel) ; 13(12)2023 Dec 16.
Article em En | MEDLINE | ID: mdl-38137955
ABSTRACT
Several animal species have been found to be susceptible to SARS-CoV-2 infection. The occurrence of infection in dogs and cats living in close contact with owners deserves particular attention from public health authorities in a One Health approach. In this study, we conducted serological screening to identify SARS-CoV-2 exposure in the sera from dogs and cats in three regions of southern Italy sampled during the years 2021 and 2022. We collected 100 serum samples in 2021 (89 from dogs and 11 from cats) and 640 in 2022 (577 from dogs and 63 from cats). Overall, the ELISA positivity rate was found to be 2.7% (20/740), with higher seroprevalence in dogs. Serum neutralization tests confirmed positivity only in two samples collected from dogs, and the assays, performed with serologically distinct SARS-CoV-2 variants, showed variant-specific positivity. This paper shows that monitoring SARS-CoV-2 exposure in animals might be affected by the viral antigenic evolution, which requires continuous updates to the serological tests used. Serological surveys are useful in understanding the true extent of exposure occurring in specific animal populations, not suffering the same limitations as molecular tests, and could help in identifying the infecting virus if tests able to characterize the immune response are used. The use of variant-specific validated serological methods should always be considered in serosurvey studies in order to determine the real impact of emerging variants on animal populations and its implications for veterinary and human health, as well as to identify potential reservoirs of the virus and its evolutionary changes.
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Itália

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Itália