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ALSUntangled #73: Lion's Mane.
Muhanna, Maya; Lund, Issac; Bromberg, Mark; Wicks, Paul; Benatar, Michael; Barnes, Benjamin; Pierce, Kaitlyn; Ratner, Dylan; Brown, Andrew; Bertorini, Tulio; Barkhaus, Paul; Carter, Greg; Mascias Cadavid, Javier; McDermott, Christopher; Glass, Jonathan D; Pattee, Gary; Armon, Carmel; Bedlack, Richard; Li, Xiaoyan.
Afiliação
  • Muhanna M; Medical College of Georgia at Augusta University, Augusta, GA, USA.
  • Lund I; Medical College of Georgia at Augusta University, Augusta, GA, USA.
  • Bromberg M; Department of Neurology, University of Utah, Salt Lake City, UT, USA.
  • Wicks P; Wicks Digital Health, Lichfield, UK.
  • Benatar M; Department of Neurology, University of Miami, Miami, FL, USA.
  • Barnes B; Medical College of Georgia at Augusta University, Augusta, GA, USA.
  • Pierce K; Neuroscience Center, University of North Carolina, Chapel Hill, NC, USA.
  • Ratner D; Tulane University, New Orleans, LA, USA.
  • Brown A; Department of Neurology, University of Miami, Miami, FL, USA.
  • Bertorini T; Department of Neurology, University of Tennessee Health Science Center, Memphis, TN, USA.
  • Barkhaus P; Department of Neurology, Medical College of Wisconsin, Milwaukee, WI, USA.
  • Carter G; Department of Rehabilitation, Elson S. Floyd College of Medicine, Washington State University, Spokane, WA, USA.
  • Mascias Cadavid J; Neurology Department, Hospital Carlos III-La Paz, Madrid, Spain.
  • McDermott C; Sheffield Institute of Translational Neuroscience, University of Sheffield, Sheffield, UK.
  • Glass JD; Department of Neurology, Emory University, Atlanta, GA, USA.
  • Pattee G; Department of Neurology, University of Nebraska Medical Center, Omaha, NE, USA.
  • Armon C; Department of Neurology, Shamir Medical Center, Tzrifin, Israel, and.
  • Bedlack R; Department of Neurology, Duke University, Durham, NC, USA.
  • Li X; Department of Neurology, Duke University, Durham, NC, USA.
Amyotroph Lateral Scler Frontotemporal Degener ; 25(3-4): 420-423, 2024 May.
Article em En | MEDLINE | ID: mdl-38141002
ABSTRACT
Lion's Mane (Hericium erinaceus) has historically been used as traditional medicine in Asia and Europe for its potential benefits in fighting infection and cancer. It has gained interest in the neurodegenerative disease field because of its mechanisms of action; these include anti-inflammation, neuroprotection, and promoting neurite growth demonstrated in various cell and animal models. A very small, double-blind, placebo-controlled trial in patients with mild cognitive impairment showed a temporary improvement in cognitive function; this finding has yet to be replicated. However, there have been no studies in ALS cell or animal models or in humans with ALS. Lion's Mane appears safe and inexpensive when consumed in powder or capsule, but one anaphylactic case was reported after a patient consumed fresh Lion's Mane mushroom. Currently, we do not have enough information to support the use of Lion's Mane for treating ALS. We support further research in ALS disease models and clinical trials to study its efficacy.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doenças Neurodegenerativas / Agaricales / Esclerose Lateral Amiotrófica País/Região como assunto: Europa Idioma: En Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doenças Neurodegenerativas / Agaricales / Esclerose Lateral Amiotrófica País/Região como assunto: Europa Idioma: En Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Estados Unidos