[Application Progress of Resting-State Functional Magnetic Resonance Imaging in Study of Default Mode Network in Patients with Vascular Cognitive Impairment].
Zhongguo Yi Liao Qi Xie Za Zhi
; 48(1): 51-56, 2024 Jan 30.
Article
em Zh
| MEDLINE
| ID: mdl-38384217
ABSTRACT
Vascular cognitive impairmentï¼VCIï¼ is a group of syndromes ranging from mild cognitive impairment to dementia caused by cerebrovascular disease, due to the lack of sensitivity and specific biomarkers, it is difficult to identify and diagnose early. Abnormal connectivity is observed in brain regions of patients with vascular cognitive disorders, locates mainly in the default mode networkï¼DMNï¼, and changes in their abnormal functional connectivity correlated with the degree of patients' cognitive impairment. Resting-state functional magnetic resonance imaging(rs-fMRI) is a commonly used method to detect the internal activity of the brain at resting state. The use of various rs-fMRI to study abnormal changes in the DMN in patients with VCI is useful to further investigate the pathogenesis of VCI and provide an objective basis for imaging. This article mainly reviews the application of rs-fMRI in the DMN in patients with VCI, bringing new perspectives for the correct diagnosis and assessment of VCI.
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Base de dados:
MEDLINE
Assunto principal:
Disfunção Cognitiva
/
Rede de Modo Padrão
Idioma:
Zh
Ano de publicação:
2024
Tipo de documento:
Article