Residential exposure to mold, dampness, and indoor air pollution and risk of respiratory tract infections: a study among children ages 11 and 12 in the Danish National Birth Cohort.
Eur J Epidemiol
; 39(3): 299-311, 2024 Mar.
Article
em En
| MEDLINE
| ID: mdl-38393605
ABSTRACT
BACKGROUND:
The burden of respiratory tract infections (RTIs) is high in childhood. Several residential exposures may affect relative rates.OBJECTIVES:
To determine risk of RTIs in children ages 11 and 12 by residential exposures.METHODS:
We included children in the Danish National Birth Cohort (DNBC) at ages 11 and 12. We estimated incidence risk ratios (IRR) and 95% confidence intervals (CI) for counts of RTIs within the last year by exposure to mold/dampness, gas stove usage, summer and winter candle-burning, fireplace usage, cats and dogs indoors, and farmhouse living. We also estimated IRR and 95% CI for RTIs for predicted scores of four extracted factors ('owned house', 'mold and dampness', 'candles', and 'density') from exploratory factor analyses (EFA).RESULTS:
We included 42 720 children with complete data. Mold/dampness was associated with all RTIs (common cold IRRadj 1.09[1.07, 1.12]; influenza IRRadj 1.10 [1.05, 1.15]; tonsillitis IRRadj 1.19 [1.10, 1.28]; conjunctivitis IRRadj 1.16 [1.02, 1.32]; and doctor-diagnosed pneumonia IRRadj 1.05 [0.90, 1.21]), as was the EFA factor 'mold/dampness' for several outcomes. Gas stove usage was associated with conjunctivitis (IRRadj 1.25 [1.05, 1.49]) and with doctor-diagnosed pneumonia (IRRadj 1.14 [0.93, 1.39]). Candle-burning during summer, but not winter, was associated with several RTIs, for tonsillitis in a dose-dependent fashion (increasing weekly frequencies vs. none [IRRadj 1.06 [0.98, 1.14], IRRadj 1.16 [1.04, 1.30], IRRadj 1.23 [1.06, 1.43], IRRadj 1.29 [1.00, 1.67], and IRRadj 1.41 [1.12, 1.78]).CONCLUSION:
Residential exposures, in particular to mold and dampness and to a lesser degree to indoor combustion sources, are related to the occurrence of RTIs in children.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Pneumonia
/
Infecções Respiratórias
/
Tonsilite
/
Poluição do Ar em Ambientes Fechados
/
Conjuntivite
País/Região como assunto:
Europa
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
Dinamarca