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A Novel Biosensor for the Detection of Glucose Concentration Using the Dual-Peak Long Period Grating in the Near- to Mid-Infrared.
Sahoo, Namita; Sun, Bing; Tan, Yidong; Zhou, Kaiming; Zhang, Lin.
Afiliação
  • Sahoo N; Aston Institute of Photonic Technologies, Aston University, Birmingham B4 7ET, UK.
  • Sun B; College of Electronic and Optical Engineering, Nanjing University of Posts and Telecommunications, Nanjing 210003, China.
  • Tan Y; Department of Precision Instrument, Tsinghua University, Beijing 100084, China.
  • Zhou K; Aston Institute of Photonic Technologies, Aston University, Birmingham B4 7ET, UK.
  • Zhang L; Aston Institute of Photonic Technologies, Aston University, Birmingham B4 7ET, UK.
Sensors (Basel) ; 24(4)2024 Feb 15.
Article em En | MEDLINE | ID: mdl-38400404
ABSTRACT
In this article, we demonstrate an improved efficient fibre sensor with a high sensitivity to measure glucose concentrations in the physiological range of human beings, operating in a broad spectral bandwidth from the near- to mid-infrared. The sensor consists of a dual-peak long period grating (DPLPG) with a period of 150 µm inscribed in an optical fibre with a diameter of 80 µm. The investigation of sensing for refractive index results in a sensitivity of ~-885.7 nm/refractive index unit (RIU) and ~2008.6 nm/RIU in the range of 1.30-1.44. The glucose measurement is achieved by the immobilisation of a layer of enzyme of glucose oxidase (GOD) onto the fibre surface for the selective enhancement of sensitivity for glucose. The sensor can measure glucose concentrations with a maximum sensitivity of -36.25 nm/(mg/mL) in the range of 0.1-3.0 mg/mL. To the best of our knowledge, this is the highest sensitivity ever achieved for a measurement of glucose with a long period grating-based sensor, indicating its potential for many applications including pharmaceutical, biomedical and food industries.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Técnicas Biossensoriais Idioma: En Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Técnicas Biossensoriais Idioma: En Ano de publicação: 2024 Tipo de documento: Article