Sex-based disparities and in-hospital outcomes of patients hospitalized with atrial fibrillation with and without dementia.
Am Heart J Plus
; 26: 100266, 2023 Feb.
Article
em En
| MEDLINE
| ID: mdl-38510193
ABSTRACT
Study objective:
We sought to evaluate the sex-based disparities and comparative in-hospital outcomes of principal AF hospitalizations in patients with and without dementia, which have not been well-studied.Design:
This is a non-interventional retrospective cohort study. Setting andparticipants:
We identified principal hospitalizations of AF in the National Inpatient Sample in adults (≥18 years old) between January 2016 and December 2019. Main outcomemeasure:
In-hospital mortality.Results:
Of 378,230 hospitalized patients with AF, 49.2 % (n = 186,039) were females and 6.1 % (n = 22,904) had dementia. The mean age (SD) was 71 (13) years. Patients with dementia had higher odds of in-hospital mortality {adjusted odds ratio (aOR) 1.48, 95 % confidence interval (CI) 1.34, 1.64, p < 0.001} and nontraumatic intracerebral hemorrhage (aOR 1.60, 95 % CI 1.04, 2.47, p = 0.032), but they had lower odds of catheter ablation (0.39, 95 % CI 0.35, 0.43, p < 0.001) and electrical cardioversion (aOR 0.33, 95 % CI 0.31, 0.35, p < 0.001). In patients with AF and dementia, compared to males, females had similar in-hospital mortality (aOR 1.00, 95 % CI 0.93, 1.07, p = 0.960), fewer gastrointestinal bleeds (aOR 0.92, 95 % CI 0.85, 0.99, p = 0.033), lower odds of getting catheter ablation (aOR 0.79, 95 % CI 0.76, 0.81, p < 0.001), and less likelihood of getting electrical cardioversion (aOR 0.78, 95 % CI 0.76, 0.79, p < 0.001).Conclusions:
Patients with AF and dementia have higher mortality and a lower likelihood of getting catheter ablation and electrical cardioversion.
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Base de dados:
MEDLINE
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article
País de afiliação:
Estados Unidos