ABSTRACT
BACKGROUND: Palmar-plantar erythrodysesthesia (PPE) is a slowly developing cutaneous reaction commonly experienced by patients treated with fluoropyrimidines. While erythrodysesthesia normally presents in a palmar-plantar distribution, it can also present with genital involvement, but this presentation is likely underreported and incorrectly attributed to an acute reaction from radiation therapy. This article aims to define erythrodysesthesia of the penis and scrotum as a rare but significant side effect of capecitabine. CASE PRESENTATION: We identified five cases of moderate to severe penis and scrotal erythrodysesthesia over a 2-year period at a large tertiary cancer center, representing an estimated incidence of 3.6% among male patients with rectal cancer who were treated with fluoropyrimidine-based chemoradiation within our institution. CONCLUSIONS: Improved understanding of erythrodysesthesia involving the penis and scrotum can facilitate early identification and treatment of symptoms, and possibly prevent the discontinuation or delay of cancer treatment in patients treated with capecitabine and similar drugs. These clinical advances would improve and prolong patient quality of life during cancer treatment and prevent complications that result in hospitalization.
Subject(s)
Capecitabine , Chemoradiotherapy , Rectal Neoplasms , Scrotum , Aged , Humans , Male , Middle Aged , Capecitabine/adverse effects , Chemoradiotherapy/adverse effects , Penis/pathology , Penis/radiation effects , Rectal Neoplasms/therapy , Rectal Neoplasms/drug therapy , Scrotum/pathologyABSTRACT
Objective: This article aims to explore care patterns and understand the impact of telehealth on nursing care in the radiation oncology setting at a comprehensive cancer center during the COVID-19 pandemic. Methods: Focus group interviews of radiation oncology nurses (n â= â18) were used to obtain data and describe current patient care patterns during the study period. Interviews were conducted over Zoom video conference, and content was analyzed. Results: Three major themes were determined: (1) the evolution of nurses' roles during the transition to telehealth, (2) the resilience of the human element, and (3) the benefits and constraints of the institution's infrastructure. Conclusions: Study results support radiation oncology nurses' ability to provide quality patient care using telehealth and can guide the expansion future care models for radiation oncology patients. Research exploring telehealth care outcomes among radiation patients is warranted. Radiation oncology nurses' training and scope of practice must be expanded to include telehealth care. As telehealth care models continue to develop, there will be a need to address training and technical disparities among certain patient demographics.
ABSTRACT
Se realizó un estudio retrospectivo con fines de investigar factores asociados a sangrado gastrointestinal alto durante el período abril 1995 a abril 1997 en el Hospital Padre Billini, de donde 35 casos el 60// correspondió al sexo masculino, los grupos de edades más afectado fue de 29-40, 41-52 y 53-64 años para un 14.3// respectivamente, el grupo sanguíneo más afectado fue el grupo ORH+ para un 42.9//, el 63// de los pacientes tenían algún tipo de hábitos tóxicos, el 31.1// refirió antecedentes de gastritis y 28.9// de úlcera péptica, el 14.3// tuvo historia de transfusiones y 22.9// antecedentes, transfusiones