ABSTRACT
Knowledge of common eye disorders and their prevention and treatment can play an essential role in reducing the visual impairment burden. A cross-sectional, questionnaire-based study was conducted from 15 November 2020 to 15 January 2021 to estimate the knowledge and awareness about common eye problems and their possible risk factors among the general population of the Hail Region, Saudi Arabia. The study also investigated the participants' sources of information about eye diseases. Participants from various areas of the Hail Region were randomly selected. There were four parts in the questionnaire based upon the general awareness about the common eye diseases, participants' knowledge and awareness of risk factors associated with eye disorders, awareness of treatment and prevention of various eye disorders, and the participants' sources of information about ocular diseases. The questionnaire was distributed to the participants by direct contact with them at eye clinics, hospitals, malls, and markets. The number of participants in the survey was 400 people, 53.8% males and 46.3% females. Cataracts were known to 31% of the participants, 43% knew about glaucoma, 66% knew about dry eyes, and 44% knew about diabetic retinopathy. Overall, 46% of the participants knew about eye problems, and the male participants had better knowledge about eye problems than the female ones. The primary sources of information about the common eye diseases were pharmacists (43.3%), family physicians (40.3%), the Internet (37.3%), the community (37.3%), television and radio (9.3%), and books/ brochures (9.5%). In the Hail Region, the general public carries a moderate awareness of preventable vision-threatening ocular disorders. However, the awareness of cataracts and glaucoma was low. The gaps in awareness can be overcome by public health promotion. In offering information about eye conditions to the general public, pharmacists may play a crucial role.
ABSTRACT
Congenital aneurysm of the right atrial appendage is a rare cardiac anomaly with only a few reported cases in the literature. Most of the cases involved adults in their third decade of life. We report a case of congenital aneurysm of the right atrial appendage in a newborn, who initially presented with jaundice and incidentally discovered systolic murmur. The diagnosis was established by enhanced CT scan of the chest and echocardiography that also showed atrial septal defect (ASD) and multiple ventricular septal defects (VSDs). Because of its rare occurrence, diagnosis is difficult and the symptoms may be confused with other causes of right atrial dilation such as Ebstein's anomaly.
ABSTRACT
OBJECTIVES: To investigate the association between angiotensin-converting enzyme (ACE) insertion/deletion (I/D) polymorphism and rheumatic heart disease (RHD) in Saudi patients. METHODS: A case-control study was conducted in Saudi RHD patients. Genomic DNA was isolated from 99 RHD patients attending the Pediatric Cardiology Clinic at the Maternity and Children Hospital, Al-Madinah, Saudi Arabia from March 2013 to June 2014, and from 145 age- and gender-matched controls. Patient clinical records were reviewed to report major and minor modified Jones' criteria for diagnosis. The diagnosis was confirmed by echocardiography. The ACE I/D polymorphism was identified by polymerase chain reaction. RESULTS: A significant difference in ACE D allele carriage (DD+ID) distribution between RHD cases and controls was identified (p=0.02, odds ratio = 3.6, 95% confidence interval: 1.2-10.8). The D allele carriage was significantly associated with development of mitral valve lesions alone (p=0.03). CONCLUSION: The ACE I/D polymorphism is associated with an increased risk of RHD in the Saudi population. Further studies are needed to confirm our findings and to understand the molecular mechanisms underlying this association.