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1.
J Med Cases ; 15(10): 283-286, 2024 Oct.
Article in English | MEDLINE | ID: mdl-39328804

ABSTRACT

Orogastric tubes (OGTs) are frequently used to administer feeds and medications to critically ill patients. They are inserted blindly, with a low first-pass success rate and frequent benign complications. OGT fractures and ingestion are exceedingly rare, with only two cases reported to date. Herein, we describe a rare case of OGT transection and ingestion in a male patient admitted for hyperacute delirium and complicated pneumonia. The OGT remnant was retrieved using an endoscope without any complications. Clinicians must be aware of this rare but potentially catastrophic complication of OGT use. OGTs must be inspected in the same manner as endotracheal tubes to ensure patient safety.

2.
J Investig Med High Impact Case Rep ; 12: 23247096241281598, 2024.
Article in English | MEDLINE | ID: mdl-39315474

ABSTRACT

Laparoscopic adjustable gastric banding (LAGB) is a bariatric procedure that was introduced in the early 1990s and offers a minimally invasive and reversible option for weight loss. Initially popular due to its simplicity and effectiveness, LAGB's long-term success has been limited by complications such as port-site infection, pouch dilatation, and gastric band erosion. Herein, we describe a rare case of gastric band erosion found incidentally during endoscopy a decade after placement. The eroded band was successfully removed using a combined endoscopic and laparoscopic approach.


Subject(s)
Gastroplasty , Incidental Findings , Laparoscopy , Obesity, Morbid , Humans , Gastroplasty/adverse effects , Gastroplasty/instrumentation , Female , Obesity, Morbid/surgery , Device Removal , Middle Aged , Adult
3.
J Investig Med High Impact Case Rep ; 12: 23247096241269864, 2024.
Article in English | MEDLINE | ID: mdl-39107990

ABSTRACT

Acute esophageal necrosis (AEN), also known as Gurvits syndrome, is a rare and potentially life-threatening condition characterized by necrosis of the esophageal mucosa. Acute esophageal necrosis is often associated with critical conditions, such as myocardial infarction, diabetic ketoacidosis (DKA), coronavirus disease 2019 (COVID-19) infection, or post-surgical complications. Patients typically present with nausea, hematemesis, acute dysphagia, and melena. Given its high mortality rate, prompt detection with upper endoscopy and early initiation of treatment are crucial. Most cases of Gurvits syndrome are managed conservatively using intravenous fluids, proton pump inhibitors, and antibiotics. Herein, we present a case series of AEN in the setting of DKA. Both patients received supportive care and were discharged in a stable condition.


Subject(s)
Diabetic Ketoacidosis , Necrosis , Humans , Diabetic Ketoacidosis/complications , Male , Middle Aged , Female , Esophagus/pathology , Esophageal Diseases/pathology , COVID-19/complications , Adult , Acute Disease
4.
J Investig Med High Impact Case Rep ; 12: 23247096241253348, 2024.
Article in English | MEDLINE | ID: mdl-38757744

ABSTRACT

Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors in the digestive tract and arise from the interstitial cells of Cajal in the mesenteric plexus. These tumors can originate in any part of the GI tract; however, a higher burden has been observed in the stomach and small intestines. Mesenteric GISTs are exceedingly rare, with unique clinicopathological features and a poorer prognosis. Herein, we describe a unique case of a 66-year-old female with a remote history of appendectomy who presented to the emergency room complaining of severe abdominal pain and vomiting. On imaging, the patient was found to have a large inflammatory mass associated with small bowel loops, and the pathology confirmed a mesenteric GIST. The tumor was resected, and the genomic test results confirmed the KIT (exon 11) mutation. Although the tumor had a low mitotic rate, the tumor was large enough to warrant the initiation of adjuvant imatinib mesylate for 36 months with regular bloodwork and imaging.


Subject(s)
Abdomen, Acute , Gastrointestinal Stromal Tumors , Imatinib Mesylate , Mesentery , Humans , Gastrointestinal Stromal Tumors/diagnosis , Gastrointestinal Stromal Tumors/pathology , Female , Aged , Abdomen, Acute/etiology , Imatinib Mesylate/therapeutic use , Mesentery/pathology , Proto-Oncogene Proteins c-kit/genetics , Tomography, X-Ray Computed , Mutation , Antineoplastic Agents/therapeutic use
5.
J Investig Med High Impact Case Rep ; 12: 23247096241274299, 2024.
Article in English | MEDLINE | ID: mdl-39171727

ABSTRACT

Ectopic pancreas, also known as heterotopic pancreas, is a rare condition in which the pancreatic tissue is found outside its usual location in the gastrointestinal (GI) tract. It is commonly asymptomatic and benign, and is often discovered incidentally during routine imaging, endoscopy, surgery, or autopsy. However, complications can arise, such as inflammation, bleeding, obstruction, or even malignant transformation, necessitating surgical intervention in some cases. Ectopic pancreas at the ampulla of Vater (EPAV) is an extremely rare condition and a diagnostic and therapeutic nightmare. Most cases have been diagnosed through invasive surgery due to concerns for malignancy, which carries significant morbidity and mortality. In our case, endoscopic snare papillectomy (ESP) was employed to establish a diagnosis. Thus far, only one other case has been reported in which ESP was used to diagnose and resect a pancreatic heterotopia at the ampulla.


Subject(s)
Ampulla of Vater , Choristoma , Pancreas , Humans , Ampulla of Vater/surgery , Choristoma/surgery , Choristoma/diagnosis , Choristoma/pathology , Female , Male , Middle Aged , Cholangiopancreatography, Endoscopic Retrograde
6.
J Investig Med High Impact Case Rep ; 12: 23247096231224328, 2024.
Article in English | MEDLINE | ID: mdl-38193443

ABSTRACT

Trichuriasis is a neglected tropical disease caused by Trichuris trichiura that spreads through the ingestion of embryonated eggs in contaminated soil, water, or food. In nonendemic areas, T trichiura infestation is very rare and sporadic and is often diagnosed in immigrants from endemic countries such as the Philippines. Whipworms feed on human blood and also erode the colonic mucosa, thereby evoking an inflammatory response. In milder forms, trichuriasis can be asymptomatic and often an incidental diagnosis on screening colonoscopy. Heavily infested patients usually present with abdominal pain, nausea, vomiting, tenesmus, chronic diarrhea, iron deficiency anemia, or stunted growth. T trichiura worms can be removed with biopsy forceps during a colonoscopy; however, most patients require a course of albendazole, mebendazole, or ivermectin. We describe a unique case of T trichiura as an incidental finding during a screening colonoscopy. The whipworms were retrieved using biopsy forceps and the patient was treated with albendazole. At the time of the colonoscopy, the patient did not exhibit any specific symptoms related to the worm infestation.


Subject(s)
Trichuriasis , Trichuris , Humans , Animals , Trichuriasis/diagnosis , Trichuriasis/drug therapy , Albendazole/therapeutic use , Incidental Findings , Colonoscopy
7.
J Investig Med High Impact Case Rep ; 12: 23247096241242569, 2024.
Article in English | MEDLINE | ID: mdl-38546011

ABSTRACT

Cocaine is an indirect-acting sympathomimetic drug that inhibits norepinephrine and dopamine reuptake in the adrenergic presynaptic cleft. Cocaine use has been associated with strokes, angina, arrhythmias, and agitation. Data on gastrointestinal complications such as mesenteric ischemia, bowel necrosis, ulceration, and perforation are scarce. Here, we present a rare case of cocaine-induced esophageal, gastric, and small bowel necrosis that contributes to the limited literature on this subject. Diagnosis of cocaine-induced gastrointestinal complications involves a combination of imaging studies, laboratory assessments, and histopathological examinations. Timely surgical resection, supported by intravenous fluids, antibiotics, and pain management, is the mainstay of treatment. The prognosis varies but is significantly influenced by the promptness and effectiveness of the intervention, underscoring the importance of vigilant clinical care in such cases.


Subject(s)
Cocaine-Related Disorders , Cocaine , Gastrointestinal Diseases , Vascular Diseases , Humans , Cocaine/adverse effects , Cocaine-Related Disorders/complications , Gastrointestinal Diseases/complications , Necrosis/chemically induced , Necrosis/complications
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