1.
Org Lett
; 7(1): 31-4, 2005 Jan 06.
Article
in English
| MEDLINE
| ID: mdl-15624970
ABSTRACT
(-)-(R)-9-(1,2-Dimethoxyethyl)anthracene (8) is successfully employed as a chiral template in the Diels-Alder/retro-Diels-Alder sequence for the preparation of alpha,beta-unsaturated lactams. The cycloadditions proceed with complete diastereoselectivity, and regioselectivity in subsequent transformations of the carbonyl groups is also excellent. Flash vacuum pyrolysis accomplishes the cycloreversion.
2.
Bioorg Med Chem
; 13(17): 5299-309, 2005 Sep 01.
Article
in English
| MEDLINE
| ID: mdl-16046136
ABSTRACT
The development of chiral anthracene templates for use in Diels-Alder/retro Diels-Alder sequences is described. A summary of past results and new progress is reported.