ABSTRACT
Gianotti-Crosti syndrome is self-limited, characterized by papular eruption with a symmetrical distribution on the limbs and face of children, and a dermatosis of unknown etiology. However, there are many suggested factors such as a number of diseases (viral or bacterial) and vaccination. We report a case of Gianotti-Crosti syndrome that had developed 3 weeks after the hepatitis B virus vaccination.
Subject(s)
Hepatitis B Vaccines/adverse effects , Skin Diseases, Vesiculobullous/etiology , Vaccination/adverse effects , Child, Preschool , Humans , Male , Skin Diseases, Vesiculobullous/pathology , SyndromeABSTRACT
Bilateral testicular tumors are a rare complication of congenital adrenal hyperplasia. It can be extremely difficult to distinguish histologically between Leydig cell tumors and adrenocortical rest hyperplasia, which may lead in some cases to unnecessary orchidectomy. A 7-yr-old boy was admitted because of precocious puberty and enlargement of testicles. Hormonal studies established the diagnosis of congenital adrenal hyperplasia due to 21-hydroxylase deficiency. Testicular biopsy revealed interlacing strands, cords, and rests of cells resembling interstitial (Leydig) cells but with no Reinke crystalloids. Here we report a case of testicular adrenal rest hyperplasia in congenital adrenal hyperplasia and discuss the pathological and clinical features and origin of this rare lesion by using immunohistochemical evaluation.
Subject(s)
Adrenal Hyperplasia, Congenital/enzymology , Adrenal Rest Tumor/enzymology , Puberty, Precocious/etiology , Steroid 21-Hydroxylase/metabolism , Testicular Neoplasms/enzymology , Testis/pathology , Adrenal Hyperplasia, Congenital/pathology , Adrenal Hyperplasia, Congenital/surgery , Adrenal Rest Tumor/pathology , Adrenal Rest Tumor/surgery , Child , Humans , Male , Testicular Neoplasms/pathology , Testicular Neoplasms/surgeryABSTRACT
Bacillary angiomatosis is an infectious disease which usually develops in immunocompromised patients. Contact with cats is implicated in its pathogenesis. We report a seven-year-old immunocompetent boy with bacillary angiomatosis without a history of direct contact with cats. The clinical diagnosis of bacillary angiomatosis was made following histopathological examination of a biopsy sample from the infected facial wound, in the vicinity of which angiomatous lesions had developed. Surprisingly, similar lesions also appeared at the donor site of the skin graft which was grafted on the facial wound. This case demonstrates that bacillary angiomatosis may also be seen in immunocompetent patients and that it may contaminate wounds without the intermediary of cats.
Subject(s)
Angiomatosis, Bacillary/diagnosis , Facial Injuries/surgery , Immunocompetence , Skin Transplantation/adverse effects , Surgical Wound Infection/etiology , Angiomatosis, Bacillary/drug therapy , Angiomatosis, Bacillary/immunology , Anti-Bacterial Agents , Child , Drug Therapy, Combination/therapeutic use , Enterobacter cloacae/isolation & purification , Facial Injuries/diagnosis , Follow-Up Studies , Humans , Leg/surgery , Male , Risk Assessment , Severity of Illness Index , Skin Transplantation/methods , Staphylococcus aureus/isolation & purification , Surgical Wound Infection/diagnosis , Treatment OutcomeSubject(s)
Hepatitis B Vaccines/adverse effects , Hepatitis B/prevention & control , Lichen Planus/chemically induced , Lichen Planus/pathology , Adult , Biopsy, Needle , Follow-Up Studies , Hepatitis B Vaccines/administration & dosage , Humans , Immunohistochemistry , Male , Risk Assessment , Severity of Illness IndexABSTRACT
PURPOSE: Pulsed ultrasonic waves have been shown to accelerate fracture healing of the long bones. The aim of this study was to evaluate the effects of low-intensity pulsed ultrasound (LIPU) on healing of mandibular fractures. MATERIALS AND METHODS: Thirty skeletally mature male New Zealand rabbits were used. Animals underwent unilateral mandibular osteotomy. The bone segments were repositioned and fixed with miniplates and miniscrews. Half of the animals received daily ultrasound treatment, 20 min/day, for 20 days. Ultrasound signals consisted of a 1.5-MHz pressure wave administered in pulses of 200 microsec with an average temporal and spatial intensity of 30 mW/cm2. Animals in the control group received sham application. All of the animals were killed on postoperative day 22. Three-point bending test, digital radiodensitometric analysis, and histologic and histomorphometric examinations were performed on the harvested hemimandibles. The data were statistically analyzed. RESULTS: Biomechanical tests revealed significant improvement in the mechanical properties of the healing bone in the LIPU-treated group. This was supported by histologic and radiologic findings. CONCLUSIONS: Results of this study suggest that LIPU improves the bone healing of mandibular fractures in rabbits.