Structural Transformation-Involved Synthesis of Nanosized ERI-Type Zeolite and Its Catalytic Property in the MTO Reaction.

Nanosized ERI-type aluminophosphate was prepared by the calcination of a precursor material (denoted as ECNU-38P) synthesized using 1,1,6,6-tetramethyl-1,6-diazacyclododecane-1,6-diium hydroxide (TDDH) as a structure-directing agent. The structure of ECNU-38P is related to ERI topology but exhibits a highly disordered manner and contains both four- and six-coordinated Al atoms. In situ XRD patterns revealed a rarely reported temperature-induced three-dimensional (3D)-to-3D structural transformation from ECNU-38P to the ordered ERI-type ECNU-38 zeolite at 573-623 K. Nanosized ERI-type silicoaluminophosphate Si-ECNU-38 was also obtained by introducing Si atoms into the synthetic system of ECNU-38P. The catalytic performance of ERI-type silicoaluminophosphates in the methanol-to-olefin (MTO) reaction was revealed to be highly related to the crystal sizes.

Fluorescent Imaging for Cysteine Detection In Vivo with High Selectivity.

As an essential amino acid, cysteine is involved in various biosynthetic and metabolic processes, such as protein synthesis, hormone synthesis, and redox homeostatic maintenance. Inordinate cysteine levels are often associated with serious diseases. Thus, designing and synthesizing a novel fluorescent probe for determining the concentration of cellular cysteine, which could indirectly monitor the prevalence of these diseases, is essential. We developed a florescence probe P-Cy with good sensitivity for cysteine detection in vivo. P-Cy only exhibited good response toward cysteine but did not show response toward other biothiols, such as homocysteine (Hcy) and glutathione (GSH). In this study, we used P-Cy by successfully imaging cellular endogenous and exogenous cysteine levels. Furthermore, P-Cy was also performed in mice to detect cysteine level, indicating that P-Cy is a powerful tool for cysteine detection in situ.