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1.
Structure-based discovery of potent WD repeat domain 5 inhibitors that demonstrate efficacy and safety in preclinical animal models.
Proc Natl Acad Sci U S A
; 120(1): e2211297120, 2023 01 03.
Article
in English
| MEDLINE | ID: mdl-36574664
2.
Interaction with WDR5 promotes target gene recognition and tumorigenesis by MYC.
Mol Cell
; 58(3): 440-52, 2015 May 07.
Article
in English
| MEDLINE | ID: mdl-25818646
3.
HER2-Directed Therapy in Advanced Gastric and Gastroesophageal Adenocarcinoma: Triumphs and Troubles.
Curr Treat Options Oncol
; 22(10): 88, 2021 08 23.
Article
in English
| MEDLINE | ID: mdl-34424404
4.
Ribosome subunit attrition and activation of the p53-MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition.
Elife
; 122024 Apr 29.
Article
in English
| MEDLINE | ID: mdl-38682900
5.
Ribosome subunit attrition and activation of the p53-MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition.
bioRxiv
; 2024 Jan 10.
Article
in English
| MEDLINE | ID: mdl-37546802
6.
New Opportunities for Minimizing Toxicity in Rectal Cancer Management.
Am Soc Clin Oncol Educ Book
; 43: e389558, 2023 Jun.
Article
in English
| MEDLINE | ID: mdl-37307515
7.
MTBP and MYC: A Dynamic Duo in Proliferation, Cancer, and Aging.
Biology (Basel)
; 11(6)2022 Jun 08.
Article
in English
| MEDLINE | ID: mdl-35741402
8.
Synergistic action of WDR5 and HDM2 inhibitors in SMARCB1-deficient cancer cells.
NAR Cancer
; 4(1): zcac007, 2022 Mar.
Article
in English
| MEDLINE | ID: mdl-35252869
9.
Evolving Landscape of Systemic Therapy for Hepatocellular Carcinoma: Breakthroughs, Toxicities, and Future Frontiers.
Am Soc Clin Oncol Educ Book
; 39: 248-260, 2019 Jan.
Article
in English
| MEDLINE | ID: mdl-31099615
10.
Haploinsufficiency of the Myc regulator Mtbp extends survival and delays tumor development in aging mice.
Aging (Albany NY)
; 8(10): 2590-2602, 2016 10 30.
Article
in English
| MEDLINE | ID: mdl-27803394
11.
MTBP is overexpressed in triple-negative breast cancer and contributes to its growth and survival.
Mol Cancer Res
; 12(9): 1216-24, 2014 Sep.
Article
in English
| MEDLINE | ID: mdl-24866769
12.
Oncogenic protein MTBP interacts with MYC to promote tumorigenesis.
Cancer Res
; 74(13): 3591-602, 2014 Jul 01.
Article
in English
| MEDLINE | ID: mdl-24786788
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