Ten-year results of the first 100 Genesis II total knee replacement procedures.

The first 100 consecutive Genesis II (Smith & Nephew; Memphis, Tenn) total knee replacements (TKR) procedures performed in 97 patients by the senior investigators (RBB, RSL) had a Kaplan-Meier survivorship of 96% +/- 2% at 12 years with any reoperation as the endpoint. Significant improvements in health-related quality-of-life outcome measures were noted. There were no revisions for implant-related factors (ie, polyethylene wear, osteolysis, or aseptic loosening). No implant demonstrated radiographic loosening. The features of this device are discussed as well as its long-term performance.

Perioperative and rehabilitation outcome after lower-limb amputation in elderly Chinese patients in Hong Kong.

PURPOSE: Major amputation of the lower limb is considered the last resort when limb salvage is impossible. The aim of this study is to determine the morbidity, mortality, and rehabilitation outcome of patients that underwent a lower-limb amputation. METHODS: A retrospective cohort study was conducted among 100 elderly patients who underwent a total of 120 lower-limb amputations in a regional hospital in Hong Kong from 1996 to 2001. RESULTS: The mean age of the amputees was 77.9 years; 58 were female. 95% of the amputations were performed because of infection with or without vascular compromise; 55 transfemoral and 60 transtibial amputations contributed 96% of the case mix. Some 43% of patients experienced early complications and 12% required re-amputation. The early (30-day) mortality rate was 15%. Only 55% of the amputees survived after 4 years. A 44% return-home rate was achieved. However, only 11% of the amputees could walk without help from other people. Although prostheses were issued to 42% of the survivors, compliance was only 53%; 24% of the survivors lost their remaining leg within 2 years. CONCLUSION: The outcome of major lower-extremity amputation remains poor. Efforts should be made to retain these limbs. When it is proven impossible, one should strive to preserve the knee joint whenever feasible.