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1.
Comput Biol Med ; 179: 108743, 2024 Jul 03.
Article in English | MEDLINE | ID: mdl-38964246

ABSTRACT

Abdominal tumor segmentation is a crucial yet challenging step during the screening and diagnosis of tumors. While 3D segmentation models provide powerful performance, they demand substantial computational resources. Additionally, in 3D data, tumors often represent a small portion, leading to imbalanced data and potentially overlooking crucial information. Conversely, 2D segmentation models have a lightweight structure, but disregard the inter-slice correlation, risking the loss of tumor in edge slices. To address these challenges, this paper proposes a novel Position-Aware and Key Slice Feature Sharing 2D tumor segmentation model (PAKS-Net). Leveraging the Swin-Transformer, we effectively model the global features within each slice, facilitating essential information extraction. Furthermore, we introduce a Position-Aware module to capture the spatial relationship between tumors and their corresponding organs, mitigating noise and interference from surrounding organ tissues. To enhance the edge slice segmentation accuracy, we employ key slices to assist in the segmentation of other slices to prioritize tumor regions. Through extensive experiments on three abdominal tumor segmentation CT datasets and a lung tumor segmentation CT dataset, PAKS-Net demonstrates superior performance, reaching 0.893, 0.769, 0.598 and 0.738 tumor DSC on the KiTS19, LiTS17, pancreas and LOTUS datasets, surpassing 3D segmentation models, while remaining computationally efficient with fewer parameters.

2.
Invest Ophthalmol Vis Sci ; 64(13): 7, 2023 10 03.
Article in English | MEDLINE | ID: mdl-37792334

ABSTRACT

Purpose: Accurate quantification measurement of tear meniscus is vital for the precise diagnosis of dry eye. In current clinical practice, the measurement of tear meniscus height (TMH) relies on doctors' manual operation. This study aims to propose a novel automatic artificial intelligence (AI) system to evaluate TMH. Methods: A total of 510 photographs obtained by the oculus camera were labeled. Three thousand and five hundred images were finally attained by data enhancement to train the neural network model parameters, and 60 were used to evaluate the model performance in segmenting the cornea and tear meniscus region. One hundred images were used to test generalization ability of the model. We modified a segmentation model of the cornea and the tear meniscus based on the UNet-like network. The output of the segmentation model is followed by a calculation module that calculates and reports the TMH. Results: Compared with ground truth (GT) manually labeled by clinicians, our modified model achieved a Dice Similarity Coefficient (DSC) and Intersection over union (Iou) of 0.99/0.98 in the corneal segmentation task and 0.92/0.86 for the detection of tear meniscus on the validation set, respectively. On the test set, the TMH automatically measured by our AI system strongly correlates with the results manually calculated by the ophthalmologists. Conclusions: We developed a fully automated and reliable AI system to obtain TMH. After large-scale clinical testing, our method could be used for dry eye screening in clinical practice.


Subject(s)
Dry Eye Syndromes , Meniscus , Humans , Artificial Intelligence , Neural Networks, Computer , Cornea , Dry Eye Syndromes/diagnosis
3.
Ther Adv Chronic Dis ; 14: 20406223221148266, 2023.
Article in English | MEDLINE | ID: mdl-36798527

ABSTRACT

Background: Corneal fluorescein sodium staining is a valuable diagnostic method for various ocular surface diseases. However, the examination results are highly dependent on the subjective experience of ophthalmologists. Objectives: To develop an artificial intelligence system based on deep learning to provide an accurate quantitative assessment of sodium fluorescein staining score and the size of cornea epithelial patchy defect. Design: A prospective study. Methods: We proposed an artificial intelligence system for automatically evaluating corneal staining scores and accurately measuring patchy corneal epithelial defects based on corneal fluorescein sodium staining images. The design incorporates two segmentation models and a classification model to forecast and assess the stained images. Meanwhile, we compare the evaluation findings from the system with ophthalmologists with varying expertise. Results: For the segmentation task of cornea boundary and cornea epithelial patchy defect area, our proposed method can achieve the performance of dice similarity coefficient (DSC) is 0.98/0.97 and Hausdorff distance (HD) is 3.60/8.39, respectively, when compared with the manually labeled gold standard. This method significantly outperforms the four leading algorithms (Unet, Unet++, Swin-Unet, and TransUnet). For the classification task, our algorithm achieves the best performance in accuracy, recall, and F1-score, which are 91.2%, 78.6%, and 79.2%, respectively. The performance of our developed system exceeds seven different approaches (Inception, ShuffleNet, Xception, EfficientNet_B7, DenseNet, ResNet, and VIT) in classification tasks. In addition, three ophthalmologists were selected to rate corneal staining images. The results showed that the performance of our artificial intelligence system significantly outperformed the junior doctors. Conclusion: The system offers a promising automated assessment method for corneal fluorescein staining, decreasing incorrect evaluations caused by ophthalmologists' subjective variance and limited knowledge.

4.
IEEE Trans Cybern ; 51(2): 839-852, 2021 Feb.
Article in English | MEDLINE | ID: mdl-32191905

ABSTRACT

Froth color can be referred to as a direct and instant indicator to the key flotation production index, for example, concentrate grade. However, it is intractable to measure the froth color robustly due to the adverse interference of time-varying and uncontrollable multisource illuminations in the flotation process monitoring. In this article, we proposed an illumination-invariant froth color measuring method by solving a structure-preserved image-to-image color translation task via an introduced Wasserstein distance-based structure-preserving CycleGAN, called WDSPCGAN. WDSPCGAN is comprised of two generative adversarial networks (GANs), which have their own discriminators but share two generators, using an improved U-net-like full convolution network to conduct the spatial structure-preserved color translation. By an adversarial game training of the two GANs, WDSPCGAN can map the color domain of froth images under any illumination to that of the referencing illumination, while maintaining the structure and texture invariance. The proposed method is validated on two public benchmark color constancy datasets and applied to an industrial bauxite flotation process. The experimental results show that WDSPCGAN can achieve illumination-invariant color features of froth images under various unknown lighting conditions while keeping their structures and textures unchanged. In addition, WDSPCGAN can be updated online to ensure its adaptability to any operational conditions. Hence, it has the potential for being popularized to the online monitoring of the flotation concentrate grade.

5.
IEEE Trans Cybern ; 50(10): 4242-4255, 2020 Oct.
Article in English | MEDLINE | ID: mdl-31021814

ABSTRACT

This paper presents a froth image statistical modeling-based online flotation process operation-state identification method by introducing a biologically inspired Gabor wavelet transform in accordance with the physiological findings in the biological vision system. It derived the latent probabilistic density models of these biologically inspired Gabor filtering responses (GFRs) based on a versatile intermediate probability modeling frame, Gaussian scale mixture model. It has demonstrated that both the real and the imaginary representation of GFR obey a Laplace distribution. Accordingly, the amplitude representation of GFR obeys a Gamma distribution. Whereas the phase representation of GFR is an important yet frequently ignored aspect in Gabor-based signal analysis; it is demonstrated to be a periodic distribution and can be expressed by a von Mises-like distribution model. Successively, a local spline regression (LSR)-based classifier that the maps scattered statistical feature points of froth images directly to the operation-state labels smoothly is introduced for the operation-state recognition. Extensive confirmatory and comparative experiments on an industrial-scale bauxite flotation process demonstrate the effectiveness and superiority of the proposed method. Performance effects on different parameter settings, e.g., parameters of Gabor kernel and dimensionalities of multivariate statistical models, are further discussed.


Subject(s)
Algorithms , Image Processing, Computer-Assisted/methods , Models, Statistical , Pattern Recognition, Automated/methods , Models, Biological , Surface Properties , Wavelet Analysis
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