1.
Org Biomol Chem
; 8(13): 3025-30, 2010 Jun 28.
Article
in English
| MEDLINE
| ID: mdl-20458418
ABSTRACT
Trifluoromethyl nitrones were obtained in high yields by condensation of various hydroxylamines with trifluoroacetaldehyde hydrate. The nucleophilic diastereoselective additions of organometallic reagents to these nitrones afforded the corresponding optically active trifluoroethyl hydroxylamines in good yields.