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1.
Arch Orthop Trauma Surg ; 141(11): 1945-1951, 2021 Nov.
Article in English | MEDLINE | ID: mdl-33715062

ABSTRACT

INTRODUCTION: Tibial intercondylar eminence fracture is a rare fracture and is commonly treated with suture, screw or bio-absorbable nail. Current literature includes little information regarding outcome of surgically treatment with bio-absorbable nails. The purpose of this study was to report the clinical and functional outcomes in patients with tibial intercondylar eminence fractures arthroscopically treated with bio-absorbable nails. METHODS: The study design was retrospective follow-up. Sixteen patients, age 11-16 years, were surgically treated with bio-absorbable nail following an intercondylar eminence fracture. Thirteen patients participate in the present follow-up study. The median follow-up time was 6.5 years. The main outcome measurement was the Knee Injury and Osteoarthritis Outcome Score (KOOS). Secondary outcome measurements consisted of: Eq5d-5L questionnaire, knee pain, knee laxity, range of motion (ROM), muscle strength, gait analyses, radiological outcomes, activity and level. RESULTS: The median KOOS scores for the five subscales were: pain 98.5 (19-100), symptoms 90.5 (54-100), ADL 100 (22-100), sport 87.5, (0-100) and QOL 88.0 (13-100), indication satisfactory outcome. Low level of gait asymmetry was observed. Almost balanced muscle strength between the injured and non-injured leg for knee extension and knee flexion strength was observed. Measurement of anterior knee laxity showed 12 patients with a knee laxity between - 1 and 2 mm. The examination of intercondylar eminence displacement at the time of follow-up showed that 12 patients had a displacement of 2 mm or less. CONCLUSION: This case series demonstrates satisfactory patient-reported and functional outcomes in the treatment of intercondylar eminence fractures in children and adolescents with bio-absorbable nails.


Subject(s)
Absorbable Implants , Tibial Fractures , Adolescent , Arthroscopy , Child , Follow-Up Studies , Fracture Fixation, Internal , Humans , Nails , Quality of Life , Retrospective Studies , Tibial Fractures/diagnostic imaging , Tibial Fractures/surgery , Treatment Outcome
2.
Knee Surg Sports Traumatol Arthrosc ; 23(1): 178-83, 2015 Jan.
Article in English | MEDLINE | ID: mdl-23575649

ABSTRACT

PURPOSE: To follow a prospective cohort of consecutive patients with MRI-verified meniscal lesions to identify pre-treatment prognostic factors for long-term results following arthroscopic or conservative treatment. METHODS: In the course of 1 year, 291 patients with knee pain and clinically suspected of meniscal lesion were referred to the regional orthopaedic division and subjected to MRI and clinical examination by an experienced surgeon. Patients with MRI-verified meniscal lesions were treated according to an arthroscopy restrictive strategy meaning that treatment was initiated by conservative treatment. Arthroscopy was only performed if satisfying pain relief was not obtained. The Lysholm score and Knee Injury and Osteoarthritis Outcome Score (KOOS) were obtained at baseline and after 12-24 months. A multiple linear regression model was used to investigate which pre-treatment prognostic factors were associated with improvement in the KOOS subscale pain from baseline to follow-up. RESULTS: An MRI-verified meniscal lesion was found in 185 patients (64%). Among these, 58% were treated successfully by conservative treatment. A high KOOS subscale pain score at baseline was associated with less improvement from baseline to follow-up. Bucket-handle lesions were associated with larger improvement from baseline to follow-up compared to flap-tear lesions. CONCLUSION: MRI findings and clinical status measured by KOOS subscale pain are prognostic for improvement among patients treated for MRI-verified meniscal lesions. Good results were observed for both operative and conservative treatment. The success rate for conservative treatment was 58%. LEVEL OF EVIDENCE: Prospective cohort study, Level II.


Subject(s)
Menisci, Tibial/surgery , Patient Outcome Assessment , Tibial Meniscus Injuries , Adult , Arthroscopy , Female , Humans , Lysholm Knee Score , Magnetic Resonance Imaging , Male , Middle Aged , Pain Measurement , Prognosis , Prospective Studies
3.
J Orthop Sports Phys Ther ; 54(5): 340-349, 2024 05.
Article in English | MEDLINE | ID: mdl-38385220

ABSTRACT

OBJECTIVE: To compare the effect of early meniscal surgery versus exercise and education with the option of later surgery on pain, function, and quality of life in young patients with a meniscal tear, taking symptom onset into account. DESIGN: Randomized controlled trial. METHODS: In a randomized controlled trial (the "Danish RCT on Exercise versus Arthroscopic Meniscal surgery for young adults" [DREAM] trial), 121 patients aged 18-40 years with a magnetic resonance imaging-verified meniscal tear were randomized to surgery or 12 weeks of supervised exercise and patient education. For this exploratory study, the analyses were stratified by symptom onset (traumatic/nontraumatic). The main outcome was the difference in change after 12 months in the mean score of 4 Knee injury and Osteoarthritis Outcome Score subscales (KOOS4) covering pain, symptoms, function in sport and recreation, and quality of life. RESULTS: Forty-two patients (69%) in the exercise therapy group and 47 (78%) in the surgery group were categorized as having a traumatic tear. We observed no difference in change in the KOOS4 after 12 months between the 2 treatment groups for either traumatic tears (18.8 versus 16.0 in the surgery versus exercise therapy groups; adjusted mean difference, 4.8 [95% confidence interval, -1.7 to 11.2]) or nontraumatic tears (20.6 versus 17.3 in the surgery versus exercise therapy groups; adjusted mean difference, 7.0 [95% confidence interval, -3.7 to 17.7]). CONCLUSION: In patients with traumatic and nontraumatic meniscus tears, early meniscal surgery did not appear superior to exercise and education in improving pain, function, and quality of life after 12 months. Further research is needed to confirm the clinical applicability of these findings. J Orthop Sports Phys Ther 2024;54(5):1-10. Epub 22 February 2024. doi:10.2519/jospt.2024.12245.


Subject(s)
Exercise Therapy , Patient Education as Topic , Quality of Life , Tibial Meniscus Injuries , Humans , Tibial Meniscus Injuries/therapy , Tibial Meniscus Injuries/surgery , Tibial Meniscus Injuries/rehabilitation , Adult , Male , Exercise Therapy/methods , Female , Young Adult , Adolescent , Arthroscopy , Meniscectomy , Time-to-Treatment
4.
NEJM Evid ; 1(2): EVIDoa2100038, 2022 02.
Article in English | MEDLINE | ID: mdl-38319181

ABSTRACT

BACKGROUND: Surgery is commonly used to treat meniscal tears; however, to our knowledge, no randomized controlled trials (RCTs) have compared surgery with nonsurgical alternatives in young adults. We hypothesized that early meniscal surgery would be superior to a strategy of exercise and education with the option of surgery later if needed. METHODS: In this pragmatic parallel-group RCT, we enrolled young adults (18-40 years of age) with magnetic resonance imaging­verified meniscal tears eligible for surgery from seven Danish hospitals. Patients were randomly assigned (1:1) to surgery (partial meniscectomy or meniscal repair) or 12-week supervised exercise therapy and education with the option of surgery later if needed. The primary outcome was the difference in change from baseline to 12 months in the mean score of four Knee Injury and Osteoarthritis Outcome Score (KOOS4) subscales covering pain, symptoms, function in sport and recreation, and quality of life, ranging from 0 (worst) to 100 (best). RESULTS: We enrolled 121 young adults (mean age, 29.7 years; 28% were female). In total, 107 participants (88%) completed the 12-month follow-up; 16 participants (26%) from the exercise group crossed over to surgery, while 8 (13%) from the surgery group did not undergo surgery. Intention-to-treat analysis showed no statistically significant difference in change between groups from baseline to 12 months in KOOS4 scores (19.2 vs. 16.4 in the surgery vs. exercise groups; adjusted mean difference, 5.4 [95% confidence interval, −0.7 to 11.4]). No difference in serious adverse events was observed (four vs. seven in the surgery and exercise groups, respectively; P=0.40). Per-protocol and as-treated analyses yielded similar results. CONCLUSIONS: Our results suggest that among young, active adults with meniscal tears, a strategy of early meniscal surgery is not superior to a strategy of exercise and education with the option of later surgery. Both groups experienced clinically relevant improvements in pain, function, and quality of life at 12 months, and one of four from the exercise group eventually had surgery. (Funded by the Danish Council for Independent Research, IMK Almene Fond, Lundbeck Foundation, Spar Nord Foundation, Danish Rheumatism Association, Association of Danish Physiotherapists Research Fund, Research Council at Næstved-Slagelse-Ringsted Hospitals, and Region Zealand; ClinicalTrials.gov number, NCT02995551.)


Subject(s)
Exercise Therapy , Meniscectomy , Tibial Meniscus Injuries , Humans , Female , Male , Adult , Tibial Meniscus Injuries/surgery , Tibial Meniscus Injuries/therapy , Tibial Meniscus Injuries/diagnostic imaging , Exercise Therapy/methods , Young Adult , Adolescent , Quality of Life , Patient Education as Topic , Treatment Outcome , Denmark , Knee Injuries/surgery , Magnetic Resonance Imaging
5.
Ugeskr Laeger ; 182(25)2020 06 15.
Article in Danish | MEDLINE | ID: mdl-32584765

ABSTRACT

Osteoid osteoma is a benign bone tumour most commonly seen in long bones, and CT-scan is the modality of choice showing nidus with surrounding sclerosis. Osteoid osteoma with an intra-articular location in the hip may lack sclerosis, and it may also lack nocturnal pain and pain relieved by non-steroidal anti-inflammatory drugs, which is most commonly seen in osteoid osteoma. This is a case report of a combination of osteoid osteoma and labrum injury in a hip of a 29-year-old woman.


Subject(s)
Bone Neoplasms , Osteoma, Osteoid , Adult , Anti-Inflammatory Agents, Non-Steroidal/therapeutic use , Bone Neoplasms/diagnostic imaging , Bone Neoplasms/drug therapy , Female , Humans , Osteoma, Osteoid/diagnostic imaging , Osteoma, Osteoid/surgery , Pain/drug therapy , Tomography, X-Ray Computed
6.
Orthop J Sports Med ; 7(10): 2325967119878136, 2019 Oct.
Article in English | MEDLINE | ID: mdl-31700938

ABSTRACT

BACKGROUND: Knee pain is common during adolescence, with Osgood-Schlatter disease (OSD) being the most frequent condition. Despite this, research regarding the long-term prognosis of OSD is limited. PURPOSE: To evaluate the prognosis 2 to 6 years after the diagnosis of OSD. STUDY DESIGN: Cohort study; Level of evidence, 3. METHODS: This retrospective cohort study included patients diagnosed with OSD at a single orthopaedic department between 2010 and 2016. Patients were contacted in 2018 and asked to complete a self-reported questionnaire regarding knee pain, knee function (Knee injury and Osteoarthritis Outcome Score [KOOS] Sports/Recreation subscale), Health-related quality of life (HRQoL) (youth version of EuroQol 5 dimensions 3 levels [EQ-5D-3L-Y]), and physical activity. RESULTS: Out of 84 patients, 43 responded. Of these, 60.5% (n = 26) reported OSD-related knee pain at follow-up (median follow-up, 3.75 years). The median symptom duration was 90 months (interquartile range, 24-150 months) for those still experiencing knee pain, and 42.9% of these reported daily knee pain. Fifty-four percent with knee pain had reduced their sports participation compared with 35.3% of those without knee pain. KOOS Sports/Recreation subscale scores were significantly lower in those with knee pain compared with those without knee pain (53 [95% CI, 42-63] vs 85 [95% CI, 76-94], respectively). Participants with knee pain reported lower HRQoL (0.71 [95% CI, 0.57-0.84]) compared with those without knee pain (0.99 [95% CI, 0.97-1.00]). CONCLUSION: This study indicates that OSD may not always be self-limiting. The lower self-reported function and HRQoL in those with continued pain may be a consequence of impaired physical activity due to knee pain.

7.
BMJ Open ; 7(8): e017436, 2017 Aug 21.
Article in English | MEDLINE | ID: mdl-28827270

ABSTRACT

INTRODUCTION: Arthroscopic surgery is a very common orthopaedic procedure. While several trials have investigated the effect of knee arthroscopy for middle-aged and older patients with meniscal tears, there is a paucity of trials comparing meniscal surgery with non-surgical treatment for younger adults. The aim of this randomised controlled trial (RCT) is to investigate if early arthroscopic surgery is superior to exercise therapy and education, with the option of later surgery if needed, in improving pain, function and quality of life in younger adults with meniscal tears. METHODS AND ANALYSIS: This is a protocol for a multicentre, parallel-group RCT conducted at six hospitals across all five healthcare regions in Denmark. 140 patients aged 18-40 years with a clinical history and symptoms consistent with a meniscal tear, verified on MRI, found eligible for meniscal surgery by an orthopaedic surgeon will be randomly allocated to one of two groups (1:1 ratio). Participants randomised to surgery will undergo either arthroscopic partial meniscectomy or meniscal repair followed by standard postsurgical care, while participants allocated to exercise and education will undergo a 12-week individualised, supervised neuromuscular and strengthening exercise programme and patient education. The primary outcome will be difference in change from baseline to 12 months in the mean score on four Knee Injury and Osteoarthritis Outcome Score subscales, covering pain, symptoms, function in sports and recreation and quality of life (Knee Injury and Osteoarthritis Outcome Score (KOOS4)) supported by the individual subscale scores allowing clinical interpretation. Alongside, the RCT an observational cohort will follow patients aged 18-40 years with clinical suspicion of a meniscal tear, but not fully eligible or declining to participate in the trial. ETHICS AND DISSEMINATION: Results will be presented in peer-reviewed journals and at international conferences. This study is approved by the Regional Committees on Health Research Ethics for Southern Denmark. REGISTRATION DETAILS: ClinicalTrials.gov (NCT02995551).


Subject(s)
Exercise Therapy , Knee Joint/surgery , Menisci, Tibial/surgery , Rupture/surgery , Tibial Meniscus Injuries/therapy , Adolescent , Adult , Denmark , Female , Humans , Knee Joint/physiopathology , Magnetic Resonance Imaging , Male , Meniscectomy , Patient Education as Topic , Quality of Life , Regression Analysis , Research Design , Young Adult
8.
Biophys Chem ; 101-102: 29-32, 2002 Dec 10.
Article in English | MEDLINE | ID: mdl-12487985
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