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1.
Ethn Health ; 24(5): 484-494, 2019 07.
Article in English | MEDLINE | ID: mdl-28669236

ABSTRACT

OBJECTIVE: Identify health perspectives among Asian Indians in greater Houston area, to guide a tailored community wide survey. DESIGN: Four focus groups of different ages, gender, and nativity were conducted at which participants were asked for their opinions about specific health topics. Key informant interviews were conducted with ten community leaders to validate focus group responses. Recordings from focus groups and key informant interviews were transcribed and analyzed. RESULTS: Diabetes, cancer, and hypertension were primary health concerns. Common themes were sedentary lifestyle and poor health literacy. Older participants were more accepting of having familial hypertension and high cholesterol. Women were more concerned about health of family members and dietary habits. Perspectives differed on eating habits, physical activity, use of Western medicine, and smoking based on nativity. Responses from key informant interviews validated focus group findings. CONCLUSION: Perspectives on health may differ among Asian Indians depending on gender, age, and nativity.


Subject(s)
Asian/psychology , Health Behavior/ethnology , Health Knowledge, Attitudes, Practice/ethnology , Adolescent , Adult , Age Factors , Complementary Therapies , Diet , Female , Focus Groups , Health Status , Humans , India/ethnology , Interviews as Topic , Male , Middle Aged , Residence Characteristics , Sedentary Behavior , Sex Factors , Texas , Young Adult
2.
Clin Trials ; 14(2): 170-179, 2017 Apr.
Article in English | MEDLINE | ID: mdl-28166647

ABSTRACT

BACKGROUND/AIMS: Trust is the cornerstone of clinical trial recruitment and retention. Efforts to decrease barriers and increase clinical trial participation among diverse populations have yielded modest results. There is an urgent need to better understand the complex interactions between trust and clinical trial participation. The process of trust-building has been a focus of intense research in the business community. Yet, little has been published about trust in oncology clinical trials or the process of building trust in clinical trials. Both clinical trials and business share common dimensions. Business strategies for building trust may be transferable to the clinical trial setting. This study was conducted to understand and utilize contemporary thinking about building trust to develop an Integrated Model of Trust that incorporates both clinical and business perspectives. METHODS: A key word-directed literature search of the PubMed, Medline, Cochrane, and Google Search databases for entries dated between 1 January 1985 and 1 September 2015 was conducted to obtain information from which to develop an Integrated Model of Trust. RESULTS: Successful trial participation requires both participants and clinical trial team members to build distinctly different types of interpersonal trust to effect recruitment and retention. They are built under conditions of significant emotional stress and time constraints among people who do not know each other and have never worked together before. Swift Trust and Traditional Trust are sequentially built during the clinical trial process. Swift trust operates during the recruitment and very early active treatment phases of the clinical trial process. Traditional trust is built over time and operates during the active treatment and surveillance stages of clinical trials. The Psychological Contract frames the participants' and clinical trial team members' interpersonal trust relationship. The "terms" of interpersonal trust are negotiated through the psychological contract. Contract renegotiation occurs in response to cyclical changes within the trust relationship throughout trial participation. CONCLUSION: The Integrated Model of Trust offers a novel framework to interrogate the process by which diverse populations and clinical trial teams build trust. To our knowledge, this is the first model of trust-building in clinical trials that frames trust development through integrated clinical and business perspectives. By focusing on the process, rather than outcomes of trust-building diverse trial participants, clinical trials teams, participants, and cancer centers may be able to better understand, measure, and manage their trust relationships in real time. Ultimately, this may foster increased recruitment and retention of diverse populations to clinical trials.


Subject(s)
Biomedical Research , Clinical Trials as Topic , Cultural Diversity , Neoplasms/therapy , Patient-Centered Care , Trust , Humans , Models, Theoretical , Patient Selection
3.
J Cancer Educ ; 32(1): 141-147, 2017 03.
Article in English | MEDLINE | ID: mdl-26546305

ABSTRACT

Online cancer risk assessment tools, which provide personalized cancer information and recommendations based on personal data input by users, are a promising cancer education approach; however, few tools have been evaluated. A randomized controlled study was conducted to compare user impressions of one tool, Cancer Risk Check (CRC), to non-personalized educational information delivered online as series of self-advancing slides (the control). CRC users (N = 1452) rated the tool to be as interesting as the control (p > .05), but users were more likely to report that the information was difficult to understand and not applicable to them (p < .05). Information seeking and sharing also were lower among CRC users; thus, although impressions of CRC were favorable, it was not shown to be superior to existing approaches. We hypothesized CRC was less effective because it contained few visual and graphical elements; therefore, CRC was compared to a text-based control (online PDF file) post hoc. CRC users rated the information to be more interesting, less difficult to understand, and better able to hold their attention (p < .05). Post hoc results suggest the visual presentation of risk is critical to tool success.


Subject(s)
Health Education/methods , Internet , Neoplasms/prevention & control , Perception , Risk Assessment , Surveys and Questionnaires , Aged , Female , Humans , Male
4.
Cancer ; 120 Suppl 7: 1122-30, 2014 Apr 01.
Article in English | MEDLINE | ID: mdl-24643650

ABSTRACT

BACKGROUND: Patient navigation programs are emerging that aim to address disparities in clinical trial participation among medically underserved populations, including racial/ethnic minorities. However, there is a lack of consensus on the role of patient navigators within the clinical trial process as well as outcome measures to evaluate program effectiveness. METHODS: A review of the literature was conducted of PubMed, Medline, CINHAL, and other sources to identify qualitative and quantitative studies on patient navigation in clinical trials. The search yielded 212 studies, of which only 12 were eligible for this review. RESULTS: The eligible studies reported on the development of programs for patient navigation in cancer clinical trials, including training and implementation among African Americans, American Indians, and Native Hawaiians. A low rate of clinical trial refusal (range, 4%-6%) was reported among patients enrolled in patient navigation programs. However, few studies reported on the efficacy of patient navigation in increasing clinical treatment trial enrollment. CONCLUSIONS: Outcome measures are proposed to assist in developing and evaluating the efficacy and/or effectiveness of patient navigation programs that aim to increase participation in cancer clinical trials. Future research is needed to evaluate the efficacy of patient navigators in addressing barriers to clinical trial participation and increasing enrollment among medically underserved cancer patients.


Subject(s)
Clinical Trials as Topic/methods , Minority Groups , Neoplasms/therapy , Patient Navigation/methods , Patient Selection , Black or African American , Ethnicity , Health Services Accessibility , Healthcare Disparities , Humans , Indians, North American , Native Hawaiian or Other Pacific Islander , Patient Acceptance of Health Care , Patient Education as Topic , Racial Groups , Research Design
5.
Cancer ; 120 Suppl 7: 1113-21, 2014 Apr 01.
Article in English | MEDLINE | ID: mdl-24643649

ABSTRACT

BACKGROUND: To ensure that National Institutes of Health-funded research is relevant to the population's needs, specific emphasis on proportional representation of minority/sex groups into National Cancer Institute (NCI) cancer centers' clinical research programs is reported to the NCI. METHODS: EMPaCT investigators at 5 regionally diverse comprehensive cancer centers compared data reported to the NCI for their most recent Cancer Center Support Grant competitive renewal to assess and compare the centers' catchment area designations, data definitions, data elements, collection processes, reporting, and performance regarding proportional representation of race/ethnicity and sex subsets. RESULTS: Cancer centers' catchment area definitions differed widely in terms of their cancer patient versus general population specificity, levels of specificity, and geographic coverage. Racial/ethnic categories were similar, yet were defined differently, across institutions. Patients' socioeconomic status and insurance status were inconsistently captured across the 5 centers. CONCLUSIONS: Catchment area definitions and the collection of patient-level demographic factors varied widely across the 5 comprehensive cancer centers. This challenged the assessment of success by cancer centers in accruing representative populations into the cancer research enterprise. Accrual of minorities was less than desired for at least 1 racial/ethnic subcategory at 4 of the 5 centers. Institutions should clearly and consistently declare their primary catchment area and the rationale and should report how race/ethnicity and sex are defined, determined, collected, and reported. More standardized, frequent, consistent collection, reporting, and review of these data are recommended, as is a commitment to collecting socioeconomic data, given that socioeconomic status is a primary driver of cancer disparities in the United States.


Subject(s)
Clinical Trials as Topic/methods , Health Services Accessibility , Healthcare Disparities/ethnology , Minority Groups , Neoplasms/therapy , Patient Selection , SEER Program , Catchment Area, Health , Female , Humans , National Cancer Institute (U.S.) , Poverty , Racial Groups , Research Design , Socioeconomic Factors , United States , Vulnerable Populations , Women
6.
J Community Health ; 39(1): 60-71, 2014 Feb.
Article in English | MEDLINE | ID: mdl-23903907

ABSTRACT

This study examines breast cancer knowledge, attitudes and screening behaviors of Hispanic women living in the South Texas colonias of Maverick and Val Verde Counties. We used the Health Belief Model to analyze the effects of HBM constructs on clinical breast exam (CBE) and mammogram screening. Using a multistage systematic sampling approach we interviewed women living within these colonias. Logistic regression analysis was used to predict CBE and mammography screening behaviors. The results indicate that knowledge, susceptibility, barriers and source of health information were statistically significant in predicting CBE among these women. In addition, background variables such as marital status and health insurance were also significant in predicting CBE. Findings further indicate that source of health information, barriers, and health insurance significantly predicts mammography screening behaviors. Results suggest that for women living in colonias along the South Texas Border socio-demographic variables play a significant role in CBE and mammography utilization.


Subject(s)
Breast Neoplasms/diagnosis , Breast Neoplasms/ethnology , Early Detection of Cancer/psychology , Health Knowledge, Attitudes, Practice/ethnology , Hispanic or Latino , Adult , Aged , Female , Health Behavior , Humans , Male , Mammography , Middle Aged , Perception , Socioeconomic Factors , Texas/epidemiology
7.
Article in English | MEDLINE | ID: mdl-38673327

ABSTRACT

This study analyzed data from a community-based prostate cancer (PCa) education and screening program (Prostate Outreach Project; POP) to enhance PCa-related knowledge among medically underserved Asian American men. It also examined PCa screening history, clinical abnormalities based on prostate-specific antigen (PSA) tests and digital rectal examination (DRE) results, and follow-up and PCa diagnosis rates. Participants-521 Asian men (251 Vietnamese, 142 Chinese, and 128 South Asians)-were offered PCa screening using PSA tests and/or DRE and an educational session on PCa. Of these men, 277 completed PCa-related knowledge surveys before and after viewing an educational video. Significant between-group differences in PCa-related knowledge were found at pre-assessment (p < 0.001) but not at post-assessment (p = 0.11), at which time all groups showed improved PCa-related knowledge. Most participants (77.9%) had never received PCa screening, but Vietnamese men had the lowest previous screening rate (17.3%). Chinese men had elevated PSA values and the highest abnormal DRE rates. Of the 125 men with abnormal screening outcomes, only 15.2% had adequate follow-up. Of the 144 men diagnosed with PCa in POP, 11.1% were Asians (seven Chinese, six Vietnamese, and three South Asian). Despite the ethnic heterogeneity among Asian men, a community outreach program may successfully enhance their PCa-related knowledge.


Subject(s)
Asian , Medically Underserved Area , Prostate-Specific Antigen , Prostatic Neoplasms , Adult , Aged , Humans , Male , Middle Aged , Asian/statistics & numerical data , Early Detection of Cancer , Health Education/methods , Health Knowledge, Attitudes, Practice , Mass Screening/methods , Prostate-Specific Antigen/blood , Prostatic Neoplasms/diagnosis , South Asian People
8.
Cancer ; 119(1): 150-7, 2013 Jan 01.
Article in English | MEDLINE | ID: mdl-22736444

ABSTRACT

BACKGROUND: The impact of race and ethnicity on the biologic features and outcome variables of women who are diagnosed with preinvasive breast cancer-ductal carcinoma in situ (DCIS)-has not been addressed widely in the published literature. METHODS: Patient demographic, clinical, and pathologic features and outcome variables were analyzed with respect to the patient's initial self-reported race/ethnicity among women who received treatment for a diagnosis of pure DCIS from 1996 to 2009. RESULTS: Of 1902 patients, 1411 were white (74.2%), 214 were African American (11.3%), 175 were Hispanic (9.1%), and 102 were Asian/Pacific Islander (5.4%). The majority of patients were between ages 41 and 70 years (83%). Patients of Hispanic and Asian/Pacific Islander descent were significantly younger than white and African American patients (P < .001). DCIS size and grade, the presence of necrosis, and the frequency of breast-conserving surgery did not differ significantly between groups. African American patients aged >70 years and Hispanic patients aged <50 years were significantly more likely to have estrogen receptor-positive DCIS than patients of other races in the same age categories (P < .001). Adjuvant radiotherapy and tamoxifen were received significantly less often by white women (P < .001). At a median follow-up of 4.8 years (range, 1-14 years), recurrence rates and the development of contralateral breast cancer did not differ significantly among racial/ethnic groups when stratified by treatments received. CONCLUSIONS: There was variation in age at presentation, biologic features, and treatment of DCIS among the different ethnic groups. Additional studies with larger numbers of ethnic minority patients are needed to confirm whether the consistent application of evidence-based treatment practices presents an opportunity for reducing disparities in patients with DCIS.


Subject(s)
Breast Neoplasms/ethnology , Carcinoma, Intraductal, Noninfiltrating/ethnology , Ethnicity , Black or African American , Aged , Breast Neoplasms/surgery , Carcinoma, Intraductal, Noninfiltrating/surgery , Female , Follow-Up Studies , Humans , Mastectomy , Middle Aged , Neoplasm Metastasis , Neoplasm Recurrence, Local , Survival Rate , Treatment Outcome , White People
9.
Multisens Res ; : 1-21, 2023 Sep 27.
Article in English | MEDLINE | ID: mdl-37758236

ABSTRACT

Autonomous Sensory Meridian Response (ASMR) is a complex sensory-perceptual phenomenon characterised by relaxing and pleasurable scalp-tingling sensations. The ASMR trait is nonuniversal, thought to have developmental origins, and a prevalence rate of 20%. Previous theory and research suggest that trait ASMR may be underlined by atypical multisensory perception from both interoceptive and exteroceptive modalities. In this study, we examined whether ASMR responders differed from nonresponders in interoceptive accuracy and multisensory processing style. Results showed that ASMR responders had lower interoceptive accuracy but a greater tendency towards sensation seeking, especially for tactile, olfactory, and gustatory modalities. Exploratory mediation analyses suggest that sensation-seeking behaviours in trait ASMR could reflect a compensatory mechanism for either deficits in interoceptive accuracy, a tendency to weight exteroceptive signals more strongly, or both. This study provides the foundations for understanding how interoceptive and exteroceptive mechanisms might explain not only the ASMR trait, but also individual differences in the ability to experience complex positive emotions more generally.

10.
Cancer ; 118(16): 4024-31, 2012 Aug 15.
Article in English | MEDLINE | ID: mdl-22252966

ABSTRACT

BACKGROUND: Health-related quality of life (HRQOL), body mass index (BMI), and physical activity (PA) levels have all been associated with prognosis following breast cancer and may explain partially the higher mortality for breast cancer in certain racial/ethnic subgroups. In this study, associations between PA, BMI, and HRQOL by race were examined in a sample of breast cancer survivors. METHODS: Measures of PA, BMI, and HRQOL as well as demographic and medical characteristics of women (N = 3013, 13% nonwhite) who participated in the Women's Healthy Eating and Living Study were assessed at baseline. Analysis of covariance was used to examine the relationship between PA and obesity with HRQOL outcomes. Statistical tests were 2-sided. RESULTS: African American women were less likely to meet guidelines for PA and more likely to be obese than women from other ethnic groups (P < .05). In adjusted models, women who met guidelines for PA reported significantly higher physical health composite (point differences ranged from 10.5 to 21.2 points, all P < .05) and vitality (point differences ranged from 9.9 to 16.5 points, all P < .05) scores than those who did not, regardless of race/ethnicity. Associations between obesity and HRQOL were mixed with fewer associations for Asian American and African American women and stronger associations for whites. CONCLUSIONS: Breast cancer survivors from racially and ethnically diverse populations have lower levels of PA and higher rates of obesity that are generally associated with poorer HRQOL. Culturally sensitive PA and weight loss interventions may improve these lifestyle characteristics and result in improved HRQOL.


Subject(s)
Body Mass Index , Breast Neoplasms/ethnology , Breast Neoplasms/psychology , Ethnicity , Exercise , Quality of Life , Survivors , Black or African American , Asian , Female , Health Behavior , Hispanic or Latino , Humans , Middle Aged , Obesity/ethnology , White People
11.
Gynecol Oncol ; 124(3): 410-6, 2012 Mar.
Article in English | MEDLINE | ID: mdl-22119991

ABSTRACT

OBJECTIVE: Few studies have examined the dietary habits of ovarian cancer survivors. Therefore, we conducted a study to assess the feasibility and impact of two dietary interventions for ovarian cancer survivors. METHODS: In this randomized, parallel-group study, 51 women (mean age, 53 years) diagnosed with stages II-IV ovarian cancer were recruited and randomly assigned to a low fat, high fiber (LFHF) diet or a modified National Cancer Institute diet supplemented with a soy-based beverage and encapsulated fruit and vegetable juice concentrates (FVJCs). Changes in clinical measures, serum carotenoid and tocopherol levels, dietary intake, anthropometry, and health-related quality of life (HRQOL) were assessed with paired t-tests. RESULTS: The recruitment rate was 25%, and the retention rate was 75% at 6 months. At baseline, 28% and 45% of women met guidelines for intake of fiber and of fruits and vegetables, respectively. After 6 months, total serum carotenoid levels and α- and ß-carotene concentrations were significantly increased in both groups (P<0.01); however, ß-carotene concentrations were increased more in the FVJC group. Serum ß-cryptoxanthin levels, fiber intake (+5.2g/day), and daily servings of juice (+0.9 servings/day) and vegetables (+1.3 servings/day) were all significantly increased in the LFHF group (all P<0.05). Serum levels of albumin, lutein and zeaxanthin, retinol, and retinyl palmitate were significantly increased in the FVJC group (all P<0.05). No changes in cancer antigen-125, anthropometry, or HRQOL were observed. CONCLUSION: Overall, this study supports the feasibility of designing dietary interventions for stages II-IV ovarian cancer survivors and provides preliminary evidence that a low fat high fiber diet and a diet supplemented with encapsulated FVJC may increase phytonutrients in ovarian cancer survivors.


Subject(s)
Dietary Fiber/administration & dosage , Ovarian Neoplasms/diet therapy , Adult , Aged , CA-125 Antigen/blood , Carotenoids/blood , Counseling , Female , Fruit , Humans , Middle Aged , Neoplasm Staging , Ovarian Neoplasms/blood , Ovarian Neoplasms/pathology , Survivors , Vegetables , alpha-Tocopherol/blood
12.
Ethn Dis ; 22(4): 479-85, 2012.
Article in English | MEDLINE | ID: mdl-23140080

ABSTRACT

OBJECTIVE: Our study aimed to assess patient's perceptions of generic drugs and utilization of generic drug discount programs. DESIGN, SETTING AND PARTICIPANTS: A survey was administered to adult participants at community health centers and community-based organizations in Houston, Texas, USA (n=525). MAIN OUTCOME MEASURES: Multivariate logistic regression was used to quantify the strength of association between generic drug perception and utilization of generic drug discount programs. RESULTS: Respondents who agreed that "Generic prescription drugs are as effective as brand name prescription drugs," were 3 times as likely to utilize generic drug discount programs (AOR: 3.0, 95% CI: 1.8-4.8, P<.001). Compared to non-Hispanic Whites, African Americans (OR: 10.2; 95% CI: 1.4-76.4) and Hispanics (OR: 10.3; 95% CI: 1.3-79.4) were 10 times as likely to agree that generic drugs have more side effects than brand name drugs. CONCLUSION: Race/ethnicity had no impact in utilization of generic drug discount programs, despite racial disparities in perception toward generic drugs' side effects and generic drugs being inferior to brand name drugs.


Subject(s)
Attitude , Drugs, Generic/economics , Prescription Drugs/economics , Adolescent , Adult , Aged , Cost Savings , Cross-Sectional Studies , Female , Health Care Costs , Health Care Surveys , Humans , Insurance, Pharmaceutical Services/economics , Logistic Models , Male , Middle Aged , Texas , Young Adult
13.
Cancer ; 117(15 Suppl): 3543-52, 2011 Aug.
Article in English | MEDLINE | ID: mdl-21780089

ABSTRACT

Despite many important efforts to increase equity in the US health care system, not all Americans have equal access to health care-or similar health outcomes. With the goal of lowering costs and increasing accessibility to health care, the nation's new health care reform legislation includes certain provisions that expand health insurance coverage to uninsured and underinsured populations, promote medical homes, and support coordination of care. These provisions may help narrow existing health care disparities. Many of the most vulnerable patients, however, may continue to have difficulty accessing and navigating the complex US health care delivery system. This article explores the unique role that patient navigation can play in improving health outcomes for racial and ethnic minorities, as well as other underserved populations, in the context of a changing healthcare environment. Patient navigators can not only facilitate improved health care access and quality for underserved populations through advocacy and care coordination, but they can also address deep-rooted issues related to distrust in providers and the health system that often lead to avoidance of health problems and non-compliance with treatment recommendations. By addressing many of the disparities associated with language and cultural differences and barriers, patient navigators can foster trust and empowerment within the communities they serve. Specific patient navigator activities are discussed, and metrics to evaluate program efforts are presented.


Subject(s)
Health Services Accessibility/organization & administration , Health Status Disparities , Healthcare Disparities/statistics & numerical data , Ethnicity , Female , Health Care Reform , Humans , Leadership , Male , Minority Groups , Needs Assessment , Professional Role , Risk Assessment , Socioeconomic Factors , United States
14.
Cancer ; 117(16): 3805-13, 2011 Aug 15.
Article in English | MEDLINE | ID: mdl-21319157

ABSTRACT

BACKGROUND: The objective of this study was to determine whether women who were participating in the Women's Healthy Eating and Living (WHEL) Study exhibited similar dietary changes, second breast cancer events, and overall survival regardless of race/ethnicity. METHODS: For this secondary analysis, the authors used data from 3013 women who were self-identified as Asian American, African American, Hispanic, or white and who were assigned randomly to a dietary intervention or a comparison group. Changes in dietary intake over time by race/ethnicity and intervention status were examined using linear mixed-effects models. Cox proportional hazards models were used to examine the effects of the intervention on the occurrence of second breast cancer events and overall survival. Statistical tests were 2-sided. RESULTS: African Americans and Hispanics consumed significantly more calories from fat (+3.2%) and less fruit (-0.7 servings daily) than Asians and whites at baseline (all P < .01). Overall, intervention participants significantly improved their dietary pattern from baseline to the end of Year 1, reducing calories from fat by 4.9% and increasing intake of fiber (+6.6 grams daily), fruit (+1.1 servings daily), and vegetables (+1.6 servings daily; all P < .05). Despite improvements in the overall dietary pattern of these survivors, the intervention did not significantly influence second breast cancer events or overall survival. CONCLUSIONS: Overall, all racial groups significantly improved their dietary pattern over time, but the maintenance of these behaviors were lower among African-American women. More research and larger minority samples are needed to determine the specific factors that improve breast cancer-specific outcomes in diverse populations of survivors.


Subject(s)
Breast Neoplasms/diet therapy , Breast Neoplasms/ethnology , Diet , Health Behavior , Black or African American , Asian People , Breast Neoplasms/epidemiology , Breast Neoplasms/mortality , Breast Neoplasms/pathology , Dietary Fats , Feeding Behavior , Female , Hispanic or Latino , Humans , Middle Aged , Neoplasm Recurrence, Local/epidemiology , Prognosis , Survivors , White People , Women's Health
15.
Psychooncology ; 20(3): 252-9, 2011 Mar.
Article in English | MEDLINE | ID: mdl-20878837

ABSTRACT

BACKGROUND: Health-related quality of life has been hypothesized to predict time to additional breast cancer events and all-cause mortality in breast cancer survivors. METHODS: Women with early-stage breast cancer (n=2967) completed the SF-36 (mental and physical health-related quality of life) and standardized psychosocial questionnaires to assess social support, optimism, hostility, and depression prior to randomization into a dietary trial. Cox regression was performed to assess whether these measures of quality of life and psychosocial functioning predicted time to additional breast cancer events and all-cause mortality; hazard ratios were the measure of association. RESULTS: There were 492 additional breast cancer events and 301 deaths occurred over a median 7.3 years (range: 0.01-10.8 years) of follow-up. In multivariate models, poorer physical health was associated with both decreased time to additional breast cancer events and all-cause mortality (p trend=0.005 and 0.004, respectively), while greater hostility predicted additional breast cancer events only (p trend=0.03). None of the other psychosocial variables predicted either outcome. The hazard ratios comparing persons with poor (bottom two quintiles) to better (top three quintiles) physical health were 1.42 (95% CI: 1.16, 1.75) for decreased time to additional breast cancer events and 1.37 (95% CI: 1.08, 1.74) for all-cause mortality. Potentially modifiable factors associated with poor physical health included higher body mass index, lower physical activity, lower alcohol consumption, and more insomnia (p<0.05 for all). CONCLUSION: Interventions to improve physical health should be tested as a means to increase time to additional breast cancer events and mortality among breast cancer survivors.


Subject(s)
Breast Neoplasms/mortality , Health Status , Quality of Life , Survivors/psychology , Adolescent , Adult , Aged , Breast Neoplasms/classification , Breast Neoplasms/pathology , Cohort Studies , Depression/psychology , Female , Follow-Up Studies , Humans , Middle Aged , Motor Activity , Neoplasm Staging , Proportional Hazards Models , Social Support , Surveys and Questionnaires , Time Factors , Young Adult
16.
Prev Chronic Dis ; 7(4): A88, 2010 Jul.
Article in English | MEDLINE | ID: mdl-20550846

ABSTRACT

BACKGROUND: Comprehensive, community-based efforts may reduce rates of childhood obesity. COMMUNITY CONTEXT: Almost half of the children in Houston are overweight or obese, even though Houston has many available resources that support good nutrition, physical activity, and prevention of weight gain among children. METHODS: We used existing resources to implement a community-based, childhood obesity prevention initiative in 2 low-income neighborhoods in Houston. On the basis of input from community members, we coordinated various activities to promote healthy living, including after-school programs, grocery store tours, wellness seminars, cooking classes, and staff wellness clubs. OUTCOME: Preliminary findings indicated that residents in the communities are using additional opportunities to participate in physical activity and nutrition education. INTERPRETATION: Implementing a successful childhood obesity prevention initiative in an urban setting is feasible with minimal funding through the use of existing resources.


Subject(s)
Community-Based Participatory Research/methods , Health Promotion/methods , Obesity/prevention & control , Child , Community Health Services/methods , Humans , Pilot Projects , School Health Services , Texas , Urban Population
17.
Health Place ; 15(2): 420-428, 2009 Jun.
Article in English | MEDLINE | ID: mdl-18835739

ABSTRACT

Residential perspectives about health in unincorporated communities are virtually unexplored. In this study, we conducted focus groups to assess individual and community health status, environmental health mediators, and systematic barriers to healthcare among African American residents of the unincorporated town, Fresno, Texas. Residents described their individual health status as excellent, but depicted the community's health status as fair. Unaffordable healthcare, limited access to healthcare, and environmental mediators were perceived to impact the Fresno community's health status. Our findings suggest a need to begin to examine health outcomes for minority residents in other unincorporated communities.


Subject(s)
Black or African American , Health Status , Residence Characteristics , Adult , Aged , Aged, 80 and over , Health Services Accessibility , Healthcare Disparities , Humans , Middle Aged , Qualitative Research
18.
J Immigr Minor Health ; 21(4): 751-760, 2019 Aug.
Article in English | MEDLINE | ID: mdl-30066057

ABSTRACT

Children and adolescents of Mexican descent residing in Hidalgo County (TX) were evaluated for exposure to organochlorine (OC) and organophosphate (OP) pesticides. A convenience sample of 60 participants enrolled in our pilot study. The lipid-adjusted serum concentrations of nine OC metabolites and creatinine-adjusted urinary concentrations of six OP metabolites were measured and compared with data from the Centers for Disease Control and Prevention's Fourth Report on Human Exposure to Environmental Chemicals. Descriptive statistics were used to summarize the concentration levels for each metabolite. Study participants were aged 5-18 years. For most of the OC and OP metabolites, our findings showed that participants had concentration levels within the distributional range of the national data. However, notable outlying levels (greater than the 95th percentile in the Fourth Report) were identified for the following OC metabolites: gamma-hexachlorocyclohexane, p,p'-dichlorodiphenyldichloroethene, and p,p'-dichlorodiphenyltrichloroethane. Among the children aged 5-11 years, one child had an outlying value for the OP metabolite: dimethylphosphate. Our findings on the levels of OC and OP pesticide exposure enhances the credibility of national estimates, and can serve as baselines for children and adolescents of Mexican descent residing in Lower Rio Grande Valley. Furthermore, our study contributes to the lacunae of knowledge regarding environmental exposures and presses further investigation of outlying OC and OP exposure levels.


Subject(s)
Environmental Exposure , Hydrocarbons, Chlorinated/metabolism , Mexican Americans , Organophosphates/metabolism , Pesticides/metabolism , Adolescent , Child , Child, Preschool , Female , Humans , Male , Pilot Projects , Texas/epidemiology
19.
Cancer Epidemiol Biomarkers Prev ; 17(3): 614-20, 2008 Mar.
Article in English | MEDLINE | ID: mdl-18323413

ABSTRACT

Epidemiologic studies fairly consistently show in postmenopausal women that reproductive steroid hormones contribute to primary breast cancer risk, and this association is strongly supported by experimental studies using laboratory animals and model systems. Evidence linking sex hormone concentrations with risk for recurrence in women diagnosed with breast cancer is limited; however, beneficial effects of antiestrogenic therapy on recurrence-free survival suggest that these hormones affect progression and risk for recurrence. This study examined whether baseline serum concentrations of estradiol, testosterone, and sex hormone binding globulin were associated with recurrence-free survival in a nested case-control cohort of women from a randomized diet trial (Women's Healthy Eating and Living Study) who were followed for >7 years after diagnosis. In 153 case-control pairs of perimenopausal and postmenopausal women in this analysis, total estradiol [hazard ratio (HR), 1.41 per unit increase in log concentration; 95% confidence interval (95% CI), 1.01-1.97], bioavailable estradiol (HR, 1.26; 95% CI, 1.03-1.53), and free estradiol (HR, 1.31; 95% CI, 1.03-1.65) concentrations were significantly associated with risk for recurrence. Recurred women had an average total estradiol concentration that was double that of nonrecurred women (22.7 versus 10.8 pg/mL; P = 0.05). Testosterone and sex hormone binding globulin concentrations did not differ between cases and controls and were not associated with risk for recurrence. Although genetic and metabolic factors likely modulate the relationship between circulating sex hormones and risk, results from this study provide evidence that higher serum estrogen concentration contributes to risk for recurrence in women diagnosed with early stage breast cancer.


Subject(s)
Breast Neoplasms/blood , Breast Neoplasms/epidemiology , Estradiol/blood , Case-Control Studies , Chi-Square Distribution , Disease-Free Survival , Female , Humans , Middle Aged , Proportional Hazards Models , Risk
20.
J Am Diet Assoc ; 108(8): 1323-9, 2008 Aug.
Article in English | MEDLINE | ID: mdl-18656572

ABSTRACT

OBJECTIVE: To assess the reported baseline dietary intake of Hispanic and non-Hispanic white breast cancer survivors in the Women's Healthy Eating and Living study, a randomized plant-based dietary intervention clinical trial. DESIGN: Dietary data from 4 days repeated 24-hour recalls within 3 weeks included daily total intake of energy, protein, carbohydrates, cholesterol, total fat, monounsaturated fat, saturated fat, polyunsaturated fat, fruit/vegetable servings, carotenoids, alcohol, caffeine, and percentage of energy from protein, carbohydrates, alcohol, and fats. SUBJECTS: One hundred sixty-five Hispanic breast cancer survivors age-matched to 165 non-Hispanic white breast cancer survivors diagnosed with Stage I, II, or IIIA primary operable breast cancer. STATISTICAL ANALYSES: Two-sample t tests and Wilcoxon rank sum tests to compare dietary intake, and logistic and ordinal logistic regression analyses to examine the association between ethnicity, alcohol, and lycopene consumption, while controlling for place of birth, education, body mass index, and time since diagnosis. RESULTS: Hispanics were more likely to be foreign-born (P<0.001), less educated (P<0.0001) and to consume higher amounts of lycopene (P=0.029), while non-Hispanic whites were more likely to consume alcohol (P=0.001). However, no differences were observed in the average amounts of alcohol consumed or total percents of energy from alcohol. Both groups consumed more than five servings of fruits and vegetables daily. Being Hispanic remained a significant predictor of lower alcohol use (P=0.004) and higher lycopene consumption (P=0.005) after controlling for place of birth, education, body mass index, and time since diagnosis. CONCLUSIONS: There are more similarities than differences in the dietary intake of Hispanic and non-Hispanic white breast cancer survivors in the Women's Healthy Eating and Living study. Further analysis is needed to determine if higher lycopene consumption shown among the Hispanic participants will translate to greater protection against breast cancer recurrence or increased survival.


Subject(s)
Breast Neoplasms/diet therapy , Diet Surveys , Diet/psychology , Hispanic or Latino/psychology , White People/psychology , Alcohol Drinking , Anticarcinogenic Agents/administration & dosage , Attitude to Health , Body Mass Index , Breast Neoplasms/ethnology , Breast Neoplasms/psychology , Carotenoids/administration & dosage , Case-Control Studies , Diet/ethnology , Female , Fruit , Guideline Adherence , Health Behavior , Humans , Lycopene , Middle Aged , Neoplasm Recurrence, Local/ethnology , Neoplasm Recurrence, Local/prevention & control , Neoplasm Recurrence, Local/psychology , Vegetables , Women's Health
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