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J Pediatr Hematol Oncol ; 45(4): e441-e445, 2023 05 01.
Article in English | MEDLINE | ID: mdl-36897312

ABSTRACT

Severe congenital neutropenia is a rare disorder. The survival and quality of life of patients radically improved through infection prevention, use of granulocyte colony-stimulating factor, and the appropriate use of antibiotics during infections. The aim of this study was to evaluate the precautions taken by families to prevent infections, the level of knowledge regarding the disease, and the impact of external factors such as education and economic status on behavior and compliance in patients and caregivers in terms of the following treatment protocols. Questionnaires were designed with the aim of determining how the social, cultural, and economic conditions of the families of children with severe congenital neutropenia affected their behavior and knowledge levels. They were completed using one-on-one video interviews with the caregivers. Thirty-one patients from 25 families were enrolled into the study. No correlations between family disease knowledge, parent education levels, working status of the mother, sibling numbers, economic status, ease of hospital access, and/or residential location were found. An increase in disease knowledge of patients and caregivers, as well as proven approaches to living with the disease, would directly correlate to increased life quality and long-term survival rates of patients.


Subject(s)
Health Knowledge, Attitudes, Practice , Neutropenia , Child , Humans , Quality of Life , Neutropenia/congenital , Congenital Bone Marrow Failure Syndromes , Granulocyte Colony-Stimulating Factor
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