ABSTRACT
A 48-year-old woman with primary biliary cirrhosis (PBC) and multiple sclerosis (MS) is reported. She presented with a visual deficit in 1975. In the course of a diagnostic evaluation, she was found to have PBC. In 1986, the diagnosis of MS was made. The patient's liver function deteriorated and liver transplantation was performed in May 1988. This is the third known case of this association.
Subject(s)
Liver Cirrhosis, Biliary/complications , Multiple Sclerosis/complications , Adult , Autoimmune Diseases , Female , Humans , Liver Cirrhosis, Biliary/immunology , Middle Aged , Multiple Sclerosis/immunologySubject(s)
Biliary Tract Diseases/etiology , Biopsy/adverse effects , Gastrointestinal Hemorrhage/etiology , Liver Cirrhosis/pathology , Adult , Angiography , Biliary Fistula/diagnostic imaging , Biliary Fistula/etiology , Celiac Artery/diagnostic imaging , Female , Gastrointestinal Hemorrhage/diagnostic imaging , Humans , Liver/diagnostic imaging , MaleABSTRACT
A patient who developed symptomatic giardiasis after a tour of the Soviet Union is presented. The diagnosis was established by duodenal aspiration. A small intestinal biopsy revealed total villous atrophy in the absence of celiac sprue or a gastrointestinal immunodeficiency syndrome, a finding not previously described. The biopsy remains normal after a single course of metronidazole (Flagyl), despite subsequent exposure to gluten.
Subject(s)
Giardiasis/pathology , Intestinal Diseases, Parasitic/pathology , Intestinal Mucosa/pathology , Atrophy , Biopsy , Female , Giardiasis/diagnosis , Giardiasis/drug therapy , Humans , Intestinal Diseases, Parasitic/diagnosis , Intestinal Diseases, Parasitic/drug therapy , Intestine, Small/pathology , Metronidazole/therapeutic use , Middle Aged , USSRABSTRACT
The case of a 39-year old white man with eosinophilic gastroenteritis is presented. The major clinical features were gastric outlet obstruction, diarrhea and massive ascites. At surgery, significant involvement of the entire gastrointestinal tract from the gastric antrum to the sigmoid colon was found. Histologic documentation of colon involvement was obtained. The response to corticosteroids was prompt and sustained. At present, he is maintained on an alternating day schedule of steroid administration.