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1.
Emerg Med J ; 38(5): 349-354, 2021 May.
Article in English | MEDLINE | ID: mdl-33597217

ABSTRACT

BACKGROUND: This study aimed to determine the rate of scalpel cricothyroidotomy conducted by a physician-paramedic prehospital trauma service over 20 years and to identify indications for, and factors associated with the intervention. METHODS: A retrospective observational study was conducted from 1 January 2000 to 31 December 2019 using clinical database records. This study was conducted in a physician-paramedic prehospital trauma service, serving a predominantly urban population of approximately 10 million in an area of approximately 2500 km2. RESULTS: Over 20 years, 37 725 patients were attended by the service, and 72 patients received a scalpel cricothyroidotomy. An immediate 'primary' cricothyroidotomy was performed in 17 patients (23.6%), and 'rescue' cricothyroidotomies were performed in 55 patients (76.4%). Forty-one patients (56.9%) were already in traumatic cardiac arrest during cricothyroidotomy. Thirty-two patients (44.4%) died on scene, and 32 (44.4%) subsequently died in hospital. Five patients (6.9%) survived to hospital discharge, and three patients (4.2%) were lost to follow-up. The most common indication for primary cricothyroidotomy was mechanical entrapment of patients (n=5, 29.4%). Difficult laryngoscopy, predominantly due to airway soiling with blood (n=15, 27.3%) was the most common indication for rescue cricothyroidotomy. The procedure was successful in 97% of cases. During the study period, 6570 prehospital emergency anaesthetics were conducted, of which 30 underwent rescue cricothyroidotomy after failed tracheal intubation (0.46%, 95% CI 0.31% to 0.65%). CONCLUSIONS: This study identifies a number of indications leading to scalpel cricothyroidotomy both as a primary procedure or after failed intubation. The main indication for scalpel cricothyroidotomy in our service was as a rescue airway for failed laryngoscopy due to a large volume of blood in the airway. Despite high levels of procedural success, 56.9% of patients were already in traumatic cardiac arrest during cricothyroidotomy, and overall mortality in patients with trauma receiving this procedure was 88.9% in our service.


Subject(s)
Emergency Medical Services/organization & administration , Emergency Medical Technicians/organization & administration , Intubation, Intratracheal/methods , Laryngeal Muscles/surgery , Physicians/organization & administration , Adult , Aged , Female , Humans , Male , Middle Aged , Retrospective Studies , Urban Population
2.
Emerg Med J ; 35(9): 532-537, 2018 Sep.
Article in English | MEDLINE | ID: mdl-29794121

ABSTRACT

INTRODUCTION: Prehospital emergency anaesthesia (PHEA or 'prehospital rapid sequence intubation') is a high-risk procedure. Standard operating procedures (SOPs) and checklists within healthcare systems have been demonstrated to reduce human error and improve patient safety. We aimed to describe the current practice of PHEA in the UK, determine the use of checklists for PHEA and describe the content, format and layout of any such checklists currently used in the UK. METHOD: A survey of UK prehospital teams was conducted to establish the incidence and conduct of PHEA practice. Results were grouped into systems delivering a high volume of PHEA per year (>50 PHEAs) and low volume (≤50 PHEAs per annum). Standard and 'crash' (immediate) induction checklists were reviewed for length, content and layout. RESULTS: 59 UK physician-led prehospital services were identified of which 43 (74%) participated. Thirty services (70%) provide PHEA and perform approximately 1629 PHEAs annually. Ten 'high volume' services deliver 84% of PHEAs per year with PHEA being performed on a median of 11% of active missions. The most common indication for PHEA was trauma. 25 of the 30 services (83%) used a PHEA checklist prior to induction of anaesthesia and 24 (80%) had an SOP for the procedure. 19 (76%) of the 'standard' checklists and 5 (50%) of the 'crash' induction checklists used were analysed. On average, standard checklists contained 169 (range: 52-286) words and 41 (range: 28-70) individual checks. The style and language complexity varied significantly between different checklists. CONCLUSION: PHEA is now performed commonly in the UK. The use of checklists for PHEA is relatively common among prehospital systems delivering this intervention. Care must be taken to limit checklist length and to use simple, unambiguous language in order to maximise the safety of this high-risk intervention.


Subject(s)
Anesthesia/methods , Emergency Medical Services/methods , Anesthesia/standards , Anesthesiology , Checklist/methods , Emergency Medical Services/trends , Humans , Intubation, Intratracheal/methods , Intubation, Intratracheal/standards , Reference Standards , Statistics, Nonparametric , Surveys and Questionnaires , United Kingdom
3.
Pediatr Emerg Care ; 34(4): 263-266, 2018 Apr.
Article in English | MEDLINE | ID: mdl-28850052

ABSTRACT

OBJECTIVES: Hanging may inflict laryngotracheal injuries and increase the potential for difficult airway management. We describe the management of pediatric hangings attended by an urban physician-led prehospital trauma service to provide information on a clinical situation encountered infrequently by most acute care clinicians. METHODS: Retrospective trauma registry-based observational study of all children younger than 16 years attended with hanging as mechanism of injury in the period between 2000 and 2014. RESULTS: Twenty-three thousand one hundred thirty patients were attended; 2415 (10%) of which were children. Of these, 32 cases (<1%) were pediatric hanging (1 case excluded due to missing data). There were 22 (71%) boys and 9 (29%) girls. Median age was 13 years. There was suicidal intent in 23 (74%) cases, and in 8 (26%) cases, hanging was accidental. There were 17 (55%) deaths, of which 14 (82%) were suicides.The doctor-paramedic team intubated 25 (80%) patients, with a 100% success rate. One (3%) patient was managed with a supraglottic airway device, and 5 (16%) patients did not require any advanced airway management. CONCLUSIONS: Pediatric hanging is rare, but has a high mortality rate. Attempted suicide is the leading cause of hangings in children and preventive measures should target psychiatric morbidity. Despite concerns about airway edema or laryngeal injury, experienced doctor-paramedic teams had no failed airway attempts.


Subject(s)
Airway Management/statistics & numerical data , Emergency Medical Services/statistics & numerical data , Neck Injuries/therapy , Suicide, Attempted/statistics & numerical data , Adolescent , Child , Female , Humans , Male , Neck Injuries/epidemiology , Neck Injuries/etiology , Registries , Retrospective Studies
4.
PLoS Med ; 14(7): e1002345, 2017 Jul.
Article in English | MEDLINE | ID: mdl-28719604

ABSTRACT

Noting that a variety of pre-hospital interventions can now be applied to treat traumatic injury, David J Lockey calls for research to determine which of these actually improve survival and reduce morbidity.


Subject(s)
Research , Wounds and Injuries/therapy , Humans , Length of Stay , Morbidity , Survival
5.
Emerg Med J ; 34(9): 606-607, 2017 Sep.
Article in English | MEDLINE | ID: mdl-28600450

ABSTRACT

BACKGROUND: Major trauma causes unanticipated critical illness and patients have often made few arrangements for what are sudden and life-changing circumstances. This can lead to financial, housing, insurance, legal and employment issues for patients and their families.A UK law firm worked with the major trauma services to develop a free and comprehensive legal service for major trauma patients and their families at a major trauma centre (MTC) in the UK. METHODS: In 2013, a legal service was established at North Bristol NHS Trust. Referrals are made by trauma nurse practitioners and it operates within a strict ethical framework. A retrospective analysis of the activity of this legal service between September 2013 and October 2015 was undertaken. RESULTS: 66 major trauma patients were seen by the legal teams at the MTC. 535 hours of free legal advice were provided on non-compensation issues-an average of 8 hours per patient. DISCUSSION: This initiative confirms a demand for the early availability of legal advice for major trauma patients to address a range of non-compensation issues as well as for identification of potential compensation claims. The availability of advice at the MTC is convenient for relatives who may be spending the majority of their time with injured relatives in hospital. More data are needed to establish the rehabilitation and health effects of receiving non-compensation advice after major injury; however, the utilisation of this service suggests that it should be considered at the UK MTCs.


Subject(s)
Legal Services/methods , Trauma Centers/statistics & numerical data , Wounds and Injuries/therapy , Adult , Critical Illness/economics , Critical Illness/therapy , Female , Humans , Legal Services/instrumentation , Male , Retrospective Studies , Trauma Centers/organization & administration , United Kingdom
6.
Crit Care ; 20(1): 362, 2016 Nov 08.
Article in English | MEDLINE | ID: mdl-27825363

ABSTRACT

BACKGROUND: Mass casualty civilian shootings present an uncommon but recurring challenge to emergency services around the world and produce unique management demands. On the background of a rising threat of transnational terrorism worldwide, emergency response strategies are of critical importance. This study aims to systematically identify, describe and appraise the quality of indexed and non-indexed literature on the pre-hospital management of modern civilian mass shootings to guide future practice. METHODS: Systematic literature searches of PubMed, Cochrane Database of Systematic Reviews and Scopus were conducted in conjunction with simple searches of non-indexed databases; Web of Science, OpenDOAR and Evidence Search. The searches were last carried out on 20 April 2016 and only identified those papers published after the 1 January 1980. Included documents had to contain descriptions, discussions or experiences of the pre-hospital management of civilian mass shootings. RESULTS: From the 494 identified manuscripts, 73 were selected on abstract and title and after full text reading 47 were selected for inclusion in analysis. The search yielded reports of 17 mass shooting events, the majority from the USA with additions from France, Norway, the UK and Kenya. Between 1994 and 2015 the shooting of 1649 people with 578 deaths at 17 separate events are described. Quality appraisal demonstrated considerable heterogeneity in reporting and revealed limited data on mass shootings globally. CONCLUSION: Key themes were identified to improve future practice: tactical emergency medical support may harmonise inner cordon interventions, a need for inter-service education on effective haemorrhage control, the value of senior triage operators and the need for regular mass casualty incident simulation.


Subject(s)
Disease Management , Emergency Medical Services/methods , Mass Casualty Incidents , Terrorism/trends , Wounds, Gunshot/therapy , France/epidemiology , Humans , Mass Casualty Incidents/mortality , Triage/methods , Wounds, Gunshot/diagnosis , Wounds, Gunshot/mortality
7.
Air Med J ; 35(3): 143-7, 2016.
Article in English | MEDLINE | ID: mdl-27255876

ABSTRACT

OBJECTIVE: Emergency medical vehicle collisions are an inherent risk for health care providers, patients, and other road users. Air ambulance services often use rapid response cars (RRCs) to maintain operational resilience. We aim to describe the operational concept of London's Air Ambulance (LAA) RRCs and activity over a 1-year period. METHODS: This was a retrospective dispatch database study. The RRC operational concept, car configuration, and training are also described. RESULTS: LAA implemented principles from motorsports and aviation including car configuration, training, navigation, and communication. RRCs were activated a total of 2,241 times during the study period (average of 6.1 activations per day). RRCs traveled a total of 22,973 km and a median of 8.7 km (interquartile range = 5-15.1) with blue lights; there were missing data for 123 (5%) activations. Furthermore, the RRCs spent a total of 28,536 minutes with blue lights and a median of 12 minutes (interquartile range = 7-18); there were missing data for 89 (4%) activations. The safety management system included 5 reports, none of which were related to serious RRC incidents. CONCLUSION: Translating lessons from aviation and motorsports, LAA has developed an RRC operation concept to improve safety and operational capacity. One-year operational data indicate high activity without any serious incidents.


Subject(s)
Air Ambulances/organization & administration , Ambulances/organization & administration , Trauma Centers/organization & administration , Urban Health Services/organization & administration , Humans , London , Retrospective Studies
8.
Crit Care ; 19: 134, 2015 Apr 01.
Article in English | MEDLINE | ID: mdl-25879683

ABSTRACT

INTRODUCTION: Rapid Sequence Induction of anaesthesia (RSI) is the recommended method to facilitate emergency tracheal intubation in trauma patients. In emergency situations, a simple and standardised RSI protocol may improve the safety and effectiveness of the procedure. A crucial component of developing a standardised protocol is the selection of induction agents. The aim of this study is to compare the safety and effectiveness of a traditional RSI protocol using etomidate and suxamethonium with a modified RSI protocol using fentanyl, ketamine and rocuronium. METHODS: We performed a comparative cohort study of major trauma patients undergoing pre-hospital RSI by a physician-led Helicopter Emergency Medical Service. Group 1 underwent RSI using etomidate and suxamethonium and Group 2 underwent RSI using fentanyl, ketamine and rocuronium. Apart from the induction agents, the RSI protocol was identical in both groups. Outcomes measured included laryngoscopy view, intubation success, haemodynamic response to laryngoscopy and tracheal intubation, and mortality. RESULTS: Compared to Group 1 (n = 116), Group 2 RSI (n = 145) produced significantly better laryngoscopy views (p = 0.013) and resulted in significantly higher first-pass intubation success (95% versus 100%; p = 0.007). A hypertensive response to laryngoscopy and tracheal intubation was less frequent following Group 2 RSI (79% versus 37%; p < 0.0001). A hypotensive response was uncommon in both groups (1% versus 6%; p = 0.05). Only one patient in each group developed true hypotension (SBP < 90 mmHg) on induction. CONCLUSIONS: In a comparative, cohort study, pre-hospital RSI using fentanyl, ketamine and rocuronium produced superior intubating conditions and a more favourable haemodynamic response to laryngoscopy and tracheal intubation. An RSI protocol using fixed ratios of these agents delivers effective pre-hospital trauma anaesthesia.


Subject(s)
Anesthesia/methods , Anesthetics, Intravenous/administration & dosage , Emergency Medical Services , Adolescent , Adult , Aged , Aged, 80 and over , Androstanols/administration & dosage , Anesthetics, Intravenous/adverse effects , Child , Child, Preschool , Etomidate/administration & dosage , Female , Fentanyl/administration & dosage , Humans , Infant , Intubation, Intratracheal/methods , Ketamine/administration & dosage , Laryngoscopy , Male , Middle Aged , Neuromuscular Nondepolarizing Agents/administration & dosage , Rocuronium , Succinylcholine/administration & dosage , Young Adult
10.
11.
Transfusion ; 53 Suppl 1: 17S-22S, 2013 Jan.
Article in English | MEDLINE | ID: mdl-23301967

ABSTRACT

This article examines how established and innovative techniques in hemorrhage control can be practically applied in a civilian physician-based prehospital trauma service. A "care bundle" of measures to control hemorrhage on scene are described. Interventions discussed include the implementation of a system to achieve simple endpoints such as shorter scene times, appropriate triage, careful patient handling, use of effective splints and measures to control external hemorrhage. More complex interventions include prehospital activation of massive hemorrhage protocols and administration of on-scene tranexamic acid, prothrombin complex concentrate, and red blood cells. Radical resuscitation interventions, such as prehospital thoracotomy for cardiac tamponade, and the potential future role of other interventions are also considered.


Subject(s)
Blood Banking/methods , Blood Component Transfusion/methods , Emergency Medical Services/methods , Hemorrhage/therapy , Wounds and Injuries/therapy , Blood Banks/standards , Blood Component Transfusion/standards , Cardiac Tamponade/surgery , Emergency Medical Services/standards , Humans , Military Medicine/methods , Military Medicine/standards , Thoracotomy/methods , Thoracotomy/standards
12.
BMC Anesthesiol ; 13(1): 21, 2013 Sep 11.
Article in English | MEDLINE | ID: mdl-24024531

ABSTRACT

BACKGROUND: In trauma patients intubated in a physician-led pre-hospital trauma service we prospectively examined the rate of misplaced tracheal tubes, the presence and nature of gross airway contamination, and the value of 'quick look' airway assessment to identify patients with subsequent difficult laryngoscopy. METHODS: Patients requiring pre-hospital intubation in a 16 month period were included. Intubation success rate, misplaced tracheal tube rate, Cormack and Lehane grade, and the presence and nature of gross airway contamination were recorded at laryngoscopy. Tube placement was verified with carbon dioxide detection and chest x-ray. After visual assessment physicians stated whether laryngoscopy was expected to be a straightforward or 'difficult'. The assessment was compared to subsequent laryngoscopy grade. RESULTS: 400 patients had attempted intubation and 399 were successfully intubated. 42 were in cardiac arrest and intubated without drugs. There were no oesophageal or misplaced tracheal tubes. Gross airway contamination was reported in 177 of 400 patients (44%), of which ¾ was from the upper airway. Unconscious patients had higher contamination rates (57%) than conscious patients (34%) (p ≤ 0.0001). As a test of difficult intubation, the 'quick look' generated sensitivity 0.597 and specificity 0.763 (PPV and NPV were 0.336 and 0.904 respectively). CONCLUSION: This study suggests that when physicians perform pre-hospital anaesthesia they have high intubation success rates and the use of ETCO2 monitoring reduces or eliminates undetected misplaced tracheal tubes. We found high rates of airway contamination; mostly blood from the upper airway. The 'quick look' airway assessment had some utility but is unreliable in isolation.

13.
Emerg Med J ; 30(6): 506-8, 2013 Jun.
Article in English | MEDLINE | ID: mdl-22833591

ABSTRACT

BACKGROUND: This study evaluated the feasibility of prehospital tissue oxygen saturation (StO2) in major trauma patients. METHODS: A prospective, pilot feasibility study carried out in a physician based prehospital trauma service. RESULTS: Prehospital StO2 was recorded on 13 patients. Continuous StO2 monitoring was achieved on all patients, despite intermittent failure of pulse oximetry and non-invasive blood pressure monitoring in six patients. No adverse outcomes of StO2 monitoring were reported. The specific equipment used was reported to be inconveniently bulky and heavy for use in the prehospital setting. CONCLUSIONS: Prehospital measurement and monitoring of StO2 is feasible in trauma patients undergoing prehospital anaesthesia and may be useful in the early identification of shock, triggering of transfusion protocols and guiding fluid resuscitation.


Subject(s)
Emergency Medical Services/methods , Oximetry , Oxygen/blood , Adolescent , Adult , Aged , Aged, 80 and over , Blood Gas Monitoring, Transcutaneous/instrumentation , Blood Gas Monitoring, Transcutaneous/methods , Blood Gas Monitoring, Transcutaneous/standards , Equipment Failure , Feasibility Studies , Female , Humans , Injury Severity Score , Male , Middle Aged , Oximetry/instrumentation , Oximetry/methods , Oximetry/standards , Pilot Projects , Prospective Studies , Young Adult
14.
Emerg Med J ; 30(3): 247-8, 2013 Mar.
Article in English | MEDLINE | ID: mdl-23349352

ABSTRACT

A case of pre-hospital administration of prothrombin complex concentrate to a patient anticoagulated with warfarin and with suspected intracranial haemorrhage is described. Effective, early reversal of anticoagulation by the time of arrival at hospital was achieved.


Subject(s)
Blood Coagulation Factors/administration & dosage , Craniocerebral Trauma/therapy , Emergency Medical Services , Accidents, Traffic , Aged, 80 and over , Female , Glasgow Coma Scale , Humans , London
16.
Crit Care ; 16(1): R24, 2012 Feb 11.
Article in English | MEDLINE | ID: mdl-22325973

ABSTRACT

INTRODUCTION: Pre-hospital airway management is a controversial subject, but there is general agreement that a small number of seriously ill or injured patients require urgent emergency tracheal intubation (ETI) and ventilation. Many European emergency medical services (EMS) systems provide physicians to care for these patients while other systems rely on paramedics (or, rarely, nurses). The ETI success rate is an important measure of provider and EMS system success and a marker of patient safety. METHODS: We conducted a systematic search of Medline and EMBASE to identify all of the published original English-language articles reporting pre-hospital ETI in adult patients. We selected all of the studies that reported ETI success rates and extracted information on the number of attempted and successful ETIs, type of provider, level of ETI training and the availability of drugs on scene. We calculated the overall success rate using meta-analysis and assessed the relationships between the ETI success rate and type of provider and between the ETI success rate and the types of drugs available on the scene. RESULTS: From 1,070 studies initially retrieved, we identified 58 original studies meeting the selection criteria. Sixty-four per cent of the non-physician-manned services and 54% of the physician-manned services reported ETI success rates but the success rate reporting was incomplete in three studies from non-physician-manned services. Median success rate was 0.905 (0.491, 1.000). In a weighted linear regression analysis, physicians as providers were significantly associated with increased success rates, 0.092 (P=0.0345). In the non-physician group, the use of drug-assisted intubation significantly increased the success rates. All physicians had access to traditional rapid sequence induction (RSI) and, comparing these to non-physicians using muscle paralytics or a traditional RSI, there still was a significant difference in success rate in favour of physicians, 0.991 and 0.955, respectively (P=0.047). CONCLUSIONS: This comprehensive meta-analysis suggests that physicians have significantly fewer pre-hospital ETI failures overall than non-physicians. This finding, which remains true when the non-physicians administer muscle paralytics or RSI, raises significant patient safety issues. In the absence of pre-hospital physicians, conducting basic or advanced airway techniques other than ETI should be strongly considered.


Subject(s)
Emergency Medical Services/methods , Emergency Medical Services/standards , Intubation, Intratracheal/methods , Patient Safety/standards , Airway Management/adverse effects , Airway Management/methods , Humans , Intubation, Intratracheal/adverse effects
18.
Crit Care ; 15(1): R26, 2011.
Article in English | MEDLINE | ID: mdl-21244667

ABSTRACT

INTRODUCTION: Although tracheal intubation (TI) in the pre-hospital setting is regularly carried out by emergency medical service (EMS) providers throughout the world, its value is widely debated. Heterogeneity in procedures, providers, patients, systems and stated outcomes, and inconsistency in data reporting make scientific reports difficult to interpret and compare, and the majority are of limited quality. To hunt down what is really known about the value of pre-hospital TI, we determined the rate of reported Utstein airway variables (28 core variables and 12 fixed-system variables) found in current scientific publications on pre-hospital TI. METHODS: We performed an all time systematic search according to the PRISMA guidelines of Medline and EMBASE to identify original research pertaining to pre-hospital TI in adult patients. RESULTS: From 1,076 identified records, 73 original papers were selected. Information was extracted according to an Utstein template for data reporting from in-the-field advanced airway management. Fifty-nine studies were from North American EMS systems. Of these, 46 (78%) described services in which non-physicians conducted TI. In 12 of the 13 non-North American EMS systems, physicians performed the pre-hospital TI. Overall, two were randomised controlled trials (RCTs), and 65 were observational studies. None of the studies presented the complete set of recommended Utstein airway variables. The median number of core variables reported was 10 (max 21, min 2, IQR 8-12), and the median number of fixed system variables was 5 (max 11, min 0, IQR 4-8). Among the most frequently reported variables were "patient category" and "service mission type", reported in 86% and 71% of the studies, respectively. Among the least-reported variables were "co-morbidity" and "type of available ventilator", both reported in 2% and 1% of the studies, respectively. CONCLUSIONS: Core data required for proper interpretation of results were frequently not recorded and reported in studies investigating TI in adults. This makes it difficult to compare scientific reports, assess their validity, and extrapolate to other EMS systems. Pre-hospital TI is a complex intervention, and terminology and study design must be improved to substantiate future evidence based clinical practice.


Subject(s)
Emergency Medical Services/methods , Intubation, Intratracheal/methods , Adult , Controlled Clinical Trials as Topic , Evidence-Based Emergency Medicine , Humans , Randomized Controlled Trials as Topic , Treatment Outcome
19.
J Trauma ; 70(5): E75-8, 2011 May.
Article in English | MEDLINE | ID: mdl-21131854

ABSTRACT

BACKGROUND: Prehospital cardiac arrest associated with trauma almost always results in death. A case of survival after prehospital thoracotomy was published in 1994 and several others have followed. This article describes the result of prehospital thoracotomy in a physician-led system for patients with stab wounds to the chest who suffered cardiac arrest on scene. METHODS: A 15-year retrospective prehospital trauma database review identified victims of stab wounds to the chest who suffered cardiac arrest on scene and had thoracotomy performed according to local standard operating procedures. RESULTS: Overall, 71 patients met inclusion criteria. Thirteen patients (18%) survived to hospital discharge. Neurologic outcome was good in 11 patients and poor in 2. Presenting cardiac rhythm was asystole in four patients, pulseless electrical activity in five, and unrecorded in the remaining four. All survivors had cardiac tamponade. The medical team was present at the time of cardiac arrest for six survivors (good neurologic outcome): arrived in the first 5 minutes after arrest in three patients (all good neurologic outcome), arrived 5 minutes to 10 minutes after arrest in two patients (one poor neurologic outcome), and in one patient (poor neurologic outcome) the period was unknown. Of the survivors, seven thoracotomies were performed by emergency physicians and six by anesthesiologists. CONCLUSIONS: Prehospital thoracotomy is a well-established procedure in this physician-led prehospital service. Results from this and other similar systems suggest that when performed for the subgroup of patients described, significant numbers of survivors with good neurologic outcome can be expected.


Subject(s)
Clinical Competence , Emergency Medical Services/methods , Resuscitation/methods , Thoracic Injuries/surgery , Thoracotomy/methods , Wounds, Penetrating/surgery , Adolescent , Adult , Humans , Male , Middle Aged , Retrospective Studies , Survivors , Treatment Outcome , Young Adult
20.
Shock ; 51(3): 284-288, 2019 03.
Article in English | MEDLINE | ID: mdl-29664833

ABSTRACT

BACKGROUND: Current management principles of hemorrhagic shock after trauma emphasize earlier transfusion therapy to prevent dilution of clotting factors and correct coagulopathy. London's Air Ambulance (LAA) was the first UK civilian prehospital service to routinely offer prehospital red blood cell (RBC) transfusion (phRTx). We investigated the effect of phRTx on mortality. METHODS: Retrospective trauma database study comparing mortality before implementation with after implementation of phRTx in exsanguinating trauma patients. Univariate logistic regression was performed for the unadjusted association between phRTx and mortality was performed, and multiple logistic regression adjusting for potential confounders. RESULTS: We identified 623 subjects with suspected major hemorrhage. We excluded 84 (13.5%) patients due to missing data on survival status. Overall 187 (62.3%) patients died in the before phRTx period and 143 (59.8%) died in the after phRTx group. There was no significant improvement in overall survival after the introduction of phRTx (P = 0.554). Examination of prehospital mortality demonstrated 126 deaths in the pre-phRTx group (42.2%) and 66 deaths in the RBC administered group (27.6%). There was a significant reduction in prehospital mortality in the group who received RBC (P < 0.001). CONCLUSIONS: phRTx was associated with increased survival to hospital, but not overall survival. The "delay death" effect of phRTx carries an impetus to further develop inhospital strategies to improve survival in severely bleeding patients.


Subject(s)
Air Ambulances , Emergency Medical Services , Erythrocyte Transfusion , Wounds and Injuries , Adult , Disease-Free Survival , Female , Hemorrhage/mortality , Hemorrhage/therapy , Humans , London/epidemiology , Male , Retrospective Studies , Survival Rate , Time Factors , Wounds and Injuries/mortality , Wounds and Injuries/therapy
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