ABSTRACT
A patient with a variety of nevus cell nevi, a congenital giant melanocytic nevus, abnormal facies, vascular anomaly of the leg, and mental retardation was examined. The patient also had neuroid elements within the giant nevus that led to the consideration of neurofibromatosis. Because neurofibromatosis is a genetically determined condition with tissue different from the neuroid elements seen in giant nevi, the two conditions are considered to be different entities. Malignant transformation of congenital giant pigmented nevi occurs, although the incidence of such transformation remains a subject of controversy.
Subject(s)
Neurofibromatosis 1/congenital , Nevus, Pigmented/congenital , Skin Neoplasms/congenital , Abnormalities, Multiple/pathology , Humans , Male , Middle Aged , Neurofibromatosis 1/pathology , Nevus, Pigmented/pathology , Skin/pathology , Skin Neoplasms/pathologyABSTRACT
Numerous diseases affect the skin and gut simultaneously. The early recognition and treatment of both components is often essential to decrease morbidity and even prevent death precipitated by gastrointestinal crises. A number of the diseases affecting both the skin and gut are discussed, with particular emphasis on recent developments.
Subject(s)
Gastrointestinal Diseases , Skin Manifestations , Acrodermatitis , Behcet Syndrome/diagnosis , Colitis, Ulcerative/complications , Crohn Disease/complications , Ehlers-Danlos Syndrome/diagnosis , Esophagitis , Humans , Malabsorption Syndromes , Malignant Carcinoid Syndrome/diagnosis , Mucocutaneous Lymph Node Syndrome/diagnosis , Sarcoma, Kaposi/diagnosis , Skin Diseases/etiology , ThrombosisSubject(s)
Darier Disease/complications , Vaccinia/complications , Adult , Humans , Inclusion Bodies, Viral , Male , Microscopy, Electron , Smallpox Vaccine , VaccinationABSTRACT
Six skin cancer detection clinics were held at a county fair booth in Turlock, California during August, 1973. Examination of sun-exposed skin areas in 605 people showed potential skin cancer in 28.6 percent of people 25 years of age or older. Of the people examined, 135 were referred to their own physicians for follow-up diagnosis and treatment of skin lesions.