ABSTRACT
Forty benign and 31 malignant breast tissues were examined using a one stage colloid-stabilising silver technique for argyrophilic nucleolar organiser regions (AgNOR). In 31 patients TNM staging was correlated to AgNOR score. There was a positive correlation with the T-stage and AgNOR score of the tumor (Spearman's rank correlation coefficient = 0.437). The N-stage and AgNOR score for breast cancers (n = 10) were inversely related, and there was a significant difference between the lymph node positive and negative groups (P less than 0.05). No significant relationship was identified between oestrogen receptor negative and positive groups and AgNOR score (P = 0.63). Mean regression analysis suggests that independent of the Bloom's grade, the AgNOR score is an indicator of tumour size.
Subject(s)
Breast Neoplasms/metabolism , Breast Neoplasms/pathology , Carcinoma/metabolism , Carcinoma/pathology , Nucleolus Organizer Region/pathology , Receptors, Estrogen/physiology , Breast Diseases/metabolism , Breast Diseases/pathology , Female , Humans , Neoplasm Staging , Regression Analysis , Silver StainingABSTRACT
Fourth branchial pouch anomalies are rarely reported. A case is described of an isolated branchial cyst which was found to contain ectopic thyroid tissue. This case, together with four others previously reported, support the theory that the thyroid gland may receive contributions from the fourth branchial pouch during development.
Subject(s)
Branchioma/pathology , Choristoma/pathology , Head and Neck Neoplasms/pathology , Thyroid Gland , Branchioma/diagnostic imaging , Child , Head and Neck Neoplasms/diagnostic imaging , Humans , Male , Thyroid Gland/diagnostic imaging , Thyroid Gland/embryology , UltrasonographyABSTRACT
Primary branchial cleft carcinoma is a diagnostic challenge. The majority of cases have been shown, following the application of rigid criteria, to have developed from an occult metastasis elsewhere. We describe what we believe to be only the second reported case in a patient who fulfils all of the established criteria.
Subject(s)
Branchioma/pathology , Carcinoma in Situ/pathology , Carcinoma, Squamous Cell/pathology , Head and Neck Neoplasms/pathology , Humans , Male , Middle AgedABSTRACT
We describe a case of malignant duodenocolic fistula in which after a radical resection of right hemicolectomy and pancreaticoduodenectomy, the duodenal defect was reconstructed using a conduit of transposed ileum. This technique, not previously described, offers an alternative to 'duodenal patching', which allows only limited duodenal resection, or gastroenterostomy with its attendant side-effects such as dumping syndrome.