ABSTRACT
Nowadays, one of the most important health and social policy issues concerning all countries is the problem of road accident rates. Traffic is one of the most important risk factors. For this reason, ridesharing companies have been launching electric scooters in Rome since June 2019 with the aim of reducing car traffic. In the absence of relevant legislations, the risk is that of facing an increase in deaths due to electric scooter crashes. We report the case of an electric scooter accident victim with cranio-encephalic trauma associated with limb injuries that caused immediate death. This case report emphasizes how the obligation of using helmets must be extended to all ages, in order to reduce the risk of increasing the number of deaths. Compulsory helmet use can reduce fatalities in all cases where high-speed crashes are not involved.
Subject(s)
Accidents, Traffic , Head Protective Devices , Humans , Risk Factors , BrainABSTRACT
Scopolamine is an alkaloid which acts as competitive antagonists to acetylcholine at central and peripheral muscarinic receptors. We report the case of a 41-year-old male convict with a 27-year history of cannabis abuse who suddenly died in the bed of his cell after having smoked buscopan® tablets. Since both abuse of substances and recent physical assaults had been reported, we opted for a comprehensive approach (post-mortem computed tomography CT (PMCT), full forensic autopsy, and toxicology testing) to determine which was the cause of the death. Virtopsy found significant cerebral edema and lungs edema that were confirmed at the autopsy and at the histopathological examination. Scopolamine was detected in peripheral blood at the toxic concentration of 14 ng/mL in blood and at 263 ng/mL in urine, and scopolamine butyl bromide at 17 ng/mL in blood and 90 ng/mL in urine. Quetiapine, mirtazapine, lorazepam, diazepam, and metabolites and valproate were also detected (at therapeutic concentrations). Inmates, especially when they have a history of drug abuse, are at risk to use any substance they can find for recreational purposes. In prisons, active surveillance on the management and assumption of prescribed drugs could avoid fatal acute intoxication.
Subject(s)
Butylscopolammonium Bromide/poisoning , Forensic Toxicology , Prisoners , Scopolamine/poisoning , Adult , Autopsy , Edema/pathology , Fatal Outcome , Humans , Male , Substance Abuse DetectionABSTRACT
Most of the work performed by the forensic expert is to find proof for different plausible hypotheses that may be used in a trial to serve justice purposes when the "identity" of a case is already unveiled. Yet the previous phase of the investigation is also of great importance, and sometimes (like in the presented case), it represents the core element of the entire investigation. The appropriate determination of the differential diagnosis between a natural death and a death of forensic interest (ie, homicide) is the first and crucial step in the classification of a case. This article analyzes the case of the body of a man found lying on the border of a country road with his wrists tied up with rope and the resulting investigation performed by the medicolegal forensic expert. In the end, as more specific examinations where performed aimed to find the truth, the final conclusions excluded a violent death and confirmed that the cause of the death was an acute myocardial infarction.
Subject(s)
Forensic Pathology/methods , Myocardial Infarction/diagnosis , Coronary Artery Disease/pathology , Coronary Vessels/pathology , Diagnosis, Differential , Homicide , Humans , Male , Myocardial Infarction/pathology , Myocardium/pathology , Restraint, Physical , Sclerosis/pathology , Vascular Calcification/pathologyABSTRACT
INTRODUCTION: Post-mortem imaging is increasingly used in forensic field in cases of natural deaths related to cardiovascular diseases, which represent the most common causes of death in developed countries. While radiological examination is generally considered to be a good complement for conventional autopsy, it was thought to have limited application in cardiovascular pathology. The aim of this study was to investigate the role of post-mortem multidetector coronary artery computed tomography in cases of sudden death in adults. MATERIALS AND METHODS: We have enrolled 11 cases, all of whom were negative for macroscopic extra-cardiac lethal findings after standard autopsy procedure. Later, from the same individuals, isolated single-organ post-mortem computed tomography coronarography (PMCTA), using an iodinated non-ionic contrast medium, was achieved. After computed tomography examination, all the isolated hearths were carried to the forensic pathologist, and a conventional histology assessment was performed on them. RESULTS: In 7 out of 11 of cadavers, a final diagnosis of myocardial infarction was made after a complete autopsy and histology procedures. Isolated hearts underwent PMCTA scanning and was confirmed in 6/11 cases, with the autopsy findings showing the presence and the localization of occlusions or severe stenoses and the extension of the myocardial hypoxic area by the extravasation of contrast medium as well. CONCLUSION: Isolated single-organ PMCTA could be considered a valid and useful tool in addition to traditional autopsy investigation (macroscopic sections and histology) in identifying the cause of death by recognizing the presence and degree of coronary artery disease and myocardial infarction area visualization.
Subject(s)
Coronary Angiography/methods , Death, Sudden, Cardiac/pathology , Multidetector Computed Tomography/methods , Myocardial Infarction/diagnostic imaging , Myocardial Infarction/pathology , Adult , Aged , Autopsy , Coronary Stenosis/diagnostic imaging , Coronary Stenosis/pathology , Diagnosis, Differential , Feasibility Studies , Humans , Middle Aged , Myocardial Infarction/classification , Myocardial Ischemia/diagnostic imaging , Myocardial Ischemia/pathology , Myocardium/pathology , Prospective Studies , Sensitivity and SpecificityABSTRACT
The aim of the study was to compare postmortem computed tomographic (CT) imaging findings from a case of hanging with the autopsy findings. The CT showed a good match with autopsy findings especially for bone, soft tissue, and spinal injuries. The CT images of the injuries of the neck obtained by CT scan clearly showed the ligature mark, the hemorrhagic suffusion in the soft tissue (thickening of derma) and in the muscles (sternocleidomastoid) of the neck. Furthermore, CT 3-dimensional reconstruction showed brain edema, fracture of the left posterior horn of the hyoid bone, and a grade 1 retrolisthesis of C5 on C6. This last finding was not detected by autopsy because of the anterior approach that is frequently used in necropsy technique. Nevertheless, the CT virtual autopsy did not show vascular findings (like Amussat mark) because a barium mixture was not injected in the body.
Subject(s)
Asphyxia/pathology , Autopsy/methods , Neck Injuries/pathology , Adult , Brain Edema/pathology , Cervical Vertebrae/injuries , Cervical Vertebrae/pathology , Forensic Pathology , Fractures, Bone/pathology , Hemorrhage/pathology , Humans , Hyoid Bone/injuries , Hyoid Bone/pathology , Imaging, Three-Dimensional , Male , Neck Muscles/pathology , Spinal Fractures/pathology , Spondylolisthesis/pathology , Tomography, X-Ray ComputedABSTRACT
The occurrence of complete decapitation as a consequence of car accident is an extremely rare event. This fatality is generally seen in pedestrians run over by trains and also in motorcyclists who impact against the tailboard of trucks. Moreover, complete transection of pedestrians and occupants of cars has been described in road accidents especially in case of vehicles traveling at a high speed. We present a case of decapitation with complete degloving injury of the neck in a patient involved in a traffic accident, and we briefly discuss the possible mechanisms producing this injury.
Subject(s)
Accidents, Traffic , Decapitation/pathology , Forensic Pathology , Humans , Male , Middle Aged , Multiple Trauma/pathology , Seat BeltsABSTRACT
Herein, we report a comparison of multidetector computed tomography (MDCT) and autopsy in the evaluation of three cases of charred human bodies. Interestingly, MDCT identified several findings useful for forensic purposes, including traumatic injuries not related to the fire, relevant vital reaction signs and detection of foreign bodies. Our results, in addition to data gathered in previous studies, indicate that MDCT is an excellent tool for imaging in postmortem investigations and that it has great potential for the forensic documentation and examination of charred bodies.
Subject(s)
Autopsy/methods , Burns/pathology , Tomography, X-Ray Computed/methods , Adult , Foreign Bodies/diagnostic imaging , Forensic Pathology , Humans , Male , Middle Aged , Wounds and Injuries/pathologyABSTRACT
We report a case of a calf-related fatality on a farm. The victim was a 60-year-old man who was possibly attempting to sexually approach the animal from behind when he was struck by it, sustaining fatal blunt injuries, mostly to the thorax. This case is reported because of its rarity and because of the particular circumstances of death. Fatal trauma associated with bovines is rare on the whole, and when it does occur it is usually caused by kicking or pushing during regular agricultural activity. Although the cause of death in our case could be determined, the circumstances and the manner of death remain speculative to some degree.
Subject(s)
Paraphilic Disorders , Wounds, Nonpenetrating/etiology , Wounds, Nonpenetrating/pathology , Animals , Cattle , Forensic Pathology , Hemorrhage/pathology , Humans , Male , Middle Aged , Rib Fractures/pathologySubject(s)
Autopsy/methods , Autopsy/trends , Forensic Pathology , Humans , Magnetic Resonance Imaging , Role , Tomography, X-Ray ComputedABSTRACT
In Italy, railway-related deaths give rise to extensive inquiries because it is mandatory for the public prosecutor to investigate the circumstances of death. For the railway embankment, normal traffic rules are not valid and the guilt of the engine driver usually cannot be proven. Consequently, these cases are very often declared as suicides without adequate evidence. Furthermore, there is a potential risk of confusion with homicide, body dismemberment or mutilation. Our medico-legal institutes are increasingly engaged with expert opinions on questions of accident, suicide or homicide because they lead to complications in the fields of insurance, criminal and civil law.
Subject(s)
Cause of Death , Decapitation/mortality , Railroads/legislation & jurisprudence , Suicide/legislation & jurisprudence , Adult , Decapitation/pathology , Diagnosis, Differential , Expert Testimony/legislation & jurisprudence , Homicide/legislation & jurisprudence , Humans , Male , Multiple Trauma/pathologyABSTRACT
The death of Adolf Hitler is one of the unsolved mysteries of the twentieth century. Numerous historians and journalists have attempted to piece together the details, but despite the interest in the forensic literature regarding the identification of the body, there has not been much scientific debate about the alleged cause of death--cyanide poisoning, gunshot injury, or both. The available literature concerning Hitler's cause of death is incomplete because the toxicological analysis has not been performed and because the skull bone fragment with a gunshot wound possibly from Hitler's corpse has not been properly examined. This has given basis for various theories, which are reviewed. We believe that mtDNA analysis of the skull fragments and of Hitler's jaw, now filed in Moscow, and samples from maternal relatives of Hitler are crucial linking the skull fragment with the gunshot wound to Hitler.
Subject(s)
Autopsy/history , Famous Persons , Forensic Anthropology , Germany , History, 20th Century , Humans , MaleABSTRACT
The question of patients information and the achievement of an informed consent to medical and/or surgical treatment by the patient still represents one of the main issue of the medical profession, having greater importance nowadays in respect to the past regarding the relationship doctor-patient and to the diagnostic-therapeutic approach to the patient. Written informed consent is a pre requisite for surgical intervention as it provides the forum for the patient to appreciate implications of the procedure and the doctor to explain details and effects of the surgery. Patients refusal is, nowadays, according to the latest orientation of the Italian Supreme Court, the major limitation to medical or surgical intervention. For these reason we have thought better to propose a written form of informed consent regarding the thyroid surgery, which implies, more than other surgery's act, the exposition of the patient to adverse iatrogenic risks and as a consequence it can expose the surgeon to criminal or civil liabilities.
Subject(s)
Informed Consent/legislation & jurisprudence , Thyroid Gland/surgery , Consent Forms , Humans , ItalyABSTRACT
Child abuse has become an increasingly serious diagnostic challenge for physicians. The clinical manifestations include malnutrition and sometimes infection. In fact, stress in children has been reported to increase corticosteroid levels. As a consequence, the thymus begins an involution process, producing a severe impairment in cellular and humoral immunity. Here, we report the case of a 7-year-old child who suffered a prolonged history of abuse and died from a systemic Pseudomonas aeruginosa infection. An initial local chronic infection propagated to the pelvic lymph nodes in an immunologically weak body and evolved into abscesses/phlegmons of the pelvic tissue, sepsis, acute respiratory distress syndrome, multiple organ failure and finally, death. Abused children have to be considered as potentially immunologically impaired patients; therefore, it is very important to screen them for opportunistic infections. Moreover, a history of unusual or recurring infections may indicate abuse, especially neglect or malnutrition. In these cases, further investigations should be conducted to determine if a protective service case should be opened. Thus, there is a need for multidisciplinary cooperation to ensure the early identification and prevention of child abuse.
Subject(s)
Child Abuse/psychology , Immunocompromised Host/immunology , Pseudomonas Infections/immunology , Stress, Psychological/immunology , Autopsy , Child , Child Abuse/diagnosis , Fatal Outcome , Humans , Immunity, Cellular/immunology , Immunity, Cellular/physiology , Pseudomonas Infections/etiology , Pseudomonas Infections/psychology , Pseudomonas aeruginosa/immunology , Pseudomonas aeruginosa/isolation & purification , Stress, Psychological/complications , Stress, Psychological/etiologyABSTRACT
Foreign body ingestion frequently occurs accidentally in the paediatric population as well as intentionally in prisoners to achieve hospitalisation, but is relatively uncommon in forensic cases and extremely rare as a method of inducing death in complex suicide. The reasons for this infrequency are many, not least the slowness of action and the lack of effectiveness in terms of lethality, regardless of the object used. In this article, we show an unplanned complex suicide carried out by ingestion of four plastic knives before hanging. Other complex suicides involving foreign body ingestion reported in the forensic literature are reviewed.
Subject(s)
Asphyxia/pathology , Foreign Bodies/pathology , Neck Injuries/pathology , Stomach/pathology , Suicide , Adult , Forensic Pathology , Humans , Male , Schizophrenic PsychologyABSTRACT
Portomesenteric vein gas can occur owing to a variety of interraleted factors such as loss of mucosal integrity and intraluminal overpressure, and the most common and serious cause is bowel ischemia, which requires urgent laparotomy. Nevertheless, when portal venous gas is caused by nonischemic causes, surgery is not required and it can be treated conservatively. So, its features should be carefully evaluated at CT scan, together with clinical findings. The authors report a case of an old male with portomesenteric venous system gas after CT colonography, without evidence of pneumatosis intestinalis or colonic perforation. A CT scan without enema was required after 24 hours in absence of worsened patient conditions, revealing the disappearance of gas in mesenteric vein and in the portal venous system.