Nonlinear amplification and decay of phase-mixed waves in compressing plasma.

Through particle-in-cell simulations, we show that plasma waves carrying trapped electrons can be amplified manyfold via compressing plasma perpendicularly to the wave vector. These simulations are the first ab initio demonstration of the conservation of nonlinear action for such waves, which contains a term independent of the field amplitude. In agreement with the theory, the maximum of amplification gain is determined by the total initial energy of the trapped-particle average motion but otherwise is insensitive to the particle distribution. Further compression destroys the wave; electrons are then untrapped at suprathermal energies and form a residual beam. As compression continues, the bump-on-tail instability is triggered each time one of the discrete modes comes in resonance with this beam. Hence, periodic bursts of the electrostatic energy are produced until a wide quasilinear plateau is formed.

Negative-mass instability in nonlinear plasma waves.

The negative-mass instability, previously found in ion traps, appears as a distinct regime of the sideband instability in nonlinear plasma waves with trapped particles. As the bounce frequency of these particles decreases with the bounce action, bunching can occur if the action distribution is inverted in trapping islands. In contrast to existing theories that also infer instabilities from the anharmonicity of bounce oscillations, spatial periodicity of the islands turns out to be unimportant, and the particle distribution can be unstable even if it is flat at the resonance. An analytical model is proposed that describes both single traps and periodic nonlinear waves and concisely generalizes the conventional description of the sideband instability in plasma waves. The theoretical results are supported by particle-in-cell simulations carried out for a regime accentuating the negative-mass instability.

The epidemiology of published norovirus outbreaks: a review of risk factors associated with attack rate and genogroup.

The purpose of this study was to examine global epidemiological trends in human norovirus (NoV) outbreaks by transmission route and setting, and describe relationships between these characteristics, viral attack rates, and the occurrence of genogroup I (GI) or genogroup II (GII) strains in outbreaks. We analysed data from 902 reverse transcriptase-polymerase chain reaction-confirmed, human NoV outbreaks abstracted from a systematic review of articles published from 1993 to 2011 and indexed under the terms 'norovirus' and 'outbreak'. Multivariate regression analyses demonstrated that foodservice and winter outbreaks were significantly associated with higher attack rates. Foodborne and waterborne outbreaks were associated with multiple strains (GI+GII). Waterborne outbreaks were significantly associated with GI strains, while healthcare-related and winter outbreaks were associated with GII strains. These results identify important trends for epidemic NoV detection, prevention, and control.

Intrinsic shoulder pain syndrome: rationale for heating and cooling in treatment.

This article reviews the literature on pathology and symptoms of the major intrinsic shoulder pain syndromes. Treatment rationale for heating and cooling agents is suggested, based on the pathology of the syndromes and the physiological effects of the agents.