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1.
Concurrent inhibition of oncogenic and wild-type RAS-GTP for cancer therapy.
Nature
; 629(8013): 919-926, 2024 May.
Article
in English
| MEDLINE | ID: mdl-38589574
2.
Inhibition of Human Uracil DNA Glycosylase Sensitizes a Large Fraction of Colorectal Cancer Cells to 5-Fluorodeoxyuridine and Raltitrexed but Not Fluorouracil.
Mol Pharmacol
; 99(6): 412-425, 2021 06.
Article
in English
| MEDLINE | ID: mdl-33795350
3.
Versatile High-Throughput Fluorescence Assay for Monitoring Cas9 Activity.
Anal Chem
; 90(11): 6913-6921, 2018 06 05.
Article
in English
| MEDLINE | ID: mdl-29756770
4.
SAMHD1 is a single-stranded nucleic acid binding protein with no active site-associated nuclease activity.
Nucleic Acids Res
; 43(13): 6486-99, 2015 Jul 27.
Article
in English
| MEDLINE | ID: mdl-26101257
5.
GTP activator and dNTP substrates of HIV-1 restriction factor SAMHD1 generate a long-lived activated state.
Proc Natl Acad Sci U S A
; 111(18): E1843-51, 2014 May 06.
Article
in English
| MEDLINE | ID: mdl-24753578
6.
Single-Stranded Nucleic Acids Bind to the Tetramer Interface of SAMHD1 and Prevent Formation of the Catalytic Homotetramer.
Biochemistry
; 55(44): 6087-6099, 2016 Nov 08.
Article
in English
| MEDLINE | ID: mdl-27775344
7.
Small molecule inhibition of SAMHD1 dNTPase by tetramer destabilization.
J Am Chem Soc
; 136(28): 9822-5, 2014 Jul 16.
Article
in English
| MEDLINE | ID: mdl-24983818
8.
Translational and Therapeutic Evaluation of RAS-GTP Inhibition by RMC-6236 in RAS-Driven Cancers.
Cancer Discov
; 14(6): 994-1017, 2024 Jun 03.
Article
in English
| MEDLINE | ID: mdl-38593348
9.
Estrogen negatively regulates epithelial wound healing and protective lipid mediator circuits in the cornea.
FASEB J
; 26(4): 1506-16, 2012 Apr.
Article
in English
| MEDLINE | ID: mdl-22186873
10.
Chemical remodeling of a cellular chaperone to target the active state of mutant KRAS.
Science
; 381(6659): 794-799, 2023 08 18.
Article
in English
| MEDLINE | ID: mdl-37590355
11.
Ultrasensitive Multi-Species Detection of CRISPR-Cas9 by a Portable Centrifugal Microfluidic Platform.
Anal Methods
; 11(5): 559-565, 2019 Feb 07.
Article
in English
| MEDLINE | ID: mdl-31565079
12.
Use of anti-CRISPR protein AcrIIA4 as a capture ligand for CRISPR/Cas9 detection.
Biosens Bioelectron
; 141: 111361, 2019 Sep 15.
Article
in English
| MEDLINE | ID: mdl-31207570
13.
A High-Throughput Enzyme-Coupled Assay for SAMHD1 dNTPase.
J Biomol Screen
; 20(6): 801-9, 2015 Jul.
Article
in English
| MEDLINE | ID: mdl-25755265
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