1.
J Infect Dis
; 215(7): 1107-1110, 2017 Apr 01.
Article
in English
| MEDLINE
| ID: mdl-28498995
ABSTRACT
We performed Ebola virus disease diagnosis and viral load estimation for Ebola cases in Sierra Leone during the late stage of the 2014-2015 outbreak (January-March 2015) and analyzed antibody and cytokine levels and the viral genome sequences. Ebola virus disease was confirmed in 86 of 1001 (9.7%) patients, with an overall case fatality rate of 46.8%. Fatal cases exhibited significantly higher levels of viral loads, cytokines, and chemokines at late stages of infection versus early stage compared with survivors. The viruses converged in a new clade within sublineage 3.2.4, which had a significantly lower case fatality rate.
Subject(s)
Ebolavirus/genetics , Hemorrhagic Fever, Ebola/epidemiology , Hemorrhagic Fever, Ebola/immunology , Viral Load , Antibodies, Viral/blood , Cytokines/blood , Disease Outbreaks , Genome, Viral , Humans , Sierra Leone/epidemiology , Survivors
2.
Coexistent lung adenocarcinoma and giant cell carcinoma in different lung lobes of the same patient.
Contemp Oncol (Pozn)
; 19(2): 163-5, 2015.
Article
in English
| MEDLINE
| ID: mdl-26034397