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1.
Eur Rev Med Pharmacol Sci ; 14(7): 643-6, 2010 Jul.
Article in English | MEDLINE | ID: mdl-20707256

ABSTRACT

This article presents a case of an 80-year-old woman with severe hematoma and consequently a compartmental syndrome of the hand complicated with acute bullous eruption due to extravasation of contrast material. Compartment syndrome of the hand has been linked to a number of various etiologies. Failure to adequately diagnose and treat compartment syndromes of the hand can lead to irreparable functional loss. In the majority of the cases extravasation results only in minimal swelling or erythema. However, severe skin necrosis, ulceration and compartment syndrome may occur with extravasation of large volumes. Compartment syndrome was diagnosed, and the patient underwent immediately fasciotomy. After fasciotomy we weekly followed up our patient with medications and after she regained the full use of the hand. We report this case to assess the importance of a careful evaluation of the intravenous administration site and close monitoring of the patient during contrast material injection to obtain minimal or prevent every kind of extravasation injuries.


Subject(s)
Compartment Syndromes/chemically induced , Extravasation of Diagnostic and Therapeutic Materials/complications , Skin Diseases, Vesiculobullous/chemically induced , Aged, 80 and over , Compartment Syndromes/surgery , Drug Eruptions/etiology , Fasciotomy , Female , Follow-Up Studies , Hand/pathology , Hematoma/chemically induced , Humans , Tomography, X-Ray Computed/adverse effects
2.
Transplant Proc ; 39(5): 1673-5, 2007 Jun.
Article in English | MEDLINE | ID: mdl-17580216

ABSTRACT

Fluoroquinolones are an important class of synthetic antibiotics and their use recently expanded with a new activity against Gram positive and anaerobics. In the literature many side effects were documented and, among them, tendinitis and subsequent tendon rupture are important causes of morbidity. The incidence is 0.14% to 0.4% but, in the kidney recipient population, the phenomenon is even more common (incidence, 12.2%-15.6%). Advanced age seems to be the most significant risk factor. Long period of hemodialysis, diabetes mellitus, hyperparathyroidism, rheumatic diseases, gout, and corticosteroids are the other predisposing factors in kidney recipients, even if they are still under discussion. All of these risk factors can create a synergistic toxicity or at least an additive effect. A case of tendinitis and a case of bilateral Achilles tendon ruptures in 2 kidney recipients are described and a brief discussion of the literature is presented.


Subject(s)
Fluoroquinolones/adverse effects , Kidney Failure, Chronic/surgery , Kidney Transplantation/adverse effects , Tendinopathy/chemically induced , Tendon Injuries/chemically induced , Female , Glomerulonephritis, IGA/complications , Humans , Kidney Failure, Chronic/etiology , Middle Aged , Postoperative Complications , Rupture/chemically induced
3.
Biomed Res Int ; 2013: 434191, 2013.
Article in English | MEDLINE | ID: mdl-24191244

ABSTRACT

The authors report their experience about the use of P.R.L. PLATELET RICH LIPOTRANSFERT method (platelet rich plasma mixed fat grafting) in 223 patients affected by soft tissue defects (ulcers, Romberg syndrome, Hemifacial atrophy, loss of substance, and signs of aging). This paper introduces the reader to PRP therapy and reviews the current literature on this emerging treatment modality, showing at the current clinical use of PRP in plastic and reconstructive surgery, with description of innovative methods and future prospects. This technique provides a promising alternative to surgery by promoting safe and natural healing. Here recent studies concerning the use of PRP in the treatment of chronic ulcers and soft tissue defect are reviewed.


Subject(s)
Adipose Tissue , Platelet-Rich Plasma , Surgery, Plastic/methods , Ulcer/therapy , Blood Platelets/pathology , Humans , Ulcer/pathology , Wound Healing
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