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1.
Microvasc Res ; 152: 104646, 2024 03.
Article in English | MEDLINE | ID: mdl-38092222

ABSTRACT

Blood flow in the gingiva, comprising the interdental papilla as well as attached and marginal gingiva, is important for maintaining of gingival function and is modulated by risk factors such as stress that may lead to periodontal disease. Marked blood flow changes mediated by the autonomic (parasympathetic and sympathetic) nervous system may be essential for gingival hemodynamics. However, differences in autonomic vasomotor responses and their functional significance in different parts of the gingiva are unclear. We examined the differences in autonomic vasomotor responses and their interactions in the gingiva of anesthetized rats. Parasympathetic vasodilation evoked by the trigeminal (lingual nerve)-mediated reflex elicited frequency-dependent blood flow increases in gingivae, with the increases being greatest in the interdental papilla. Parasympathetic blood flow increases were significantly reduced by intravenous administration of the atropine and VIP antagonist. The blood flow increase evoked by acetylcholine administration was higher in the interdental papilla than in the attached gingiva, whereas that evoked by VIP agonist administration was greater in the attached gingiva than in the interdental papilla. Activation of the cervical sympathetic nerves decreased gingival blood flow and inhibited parasympathetically induced blood flow increases. Our results suggest that trigeminal-parasympathetic reflex vasodilation 1) is more involved in the regulation of blood flow in the interdental papilla than in the other parts of the gingiva, 2) is mediated by cholinergic (interdental papilla) and VIPergic systems (attached gingiva), and 3) is inhibited by excess sympathetic activity. These results suggest a role in the etiology of periodontal diseases during mental stress.


Subject(s)
Gingiva , Sympathetic Nervous System , Rats , Animals , Gingiva/blood supply , Vasodilation , Atropine/pharmacology
2.
Medicina (Kaunas) ; 60(7)2024 Jul 17.
Article in English | MEDLINE | ID: mdl-39064586

ABSTRACT

Background and Objectives: The key factor that enables osteoblastic activity and the formation of new bone, as well as gingiva, during orthodontic tooth extrusion (OE) is the periodontal ligament. The reaction of periodontal tissues associated with changes in the gingiva is a part of orthodontic tooth displacement. The aim of this study was to examine the effect of OE on the width of the zone of the keratinized and attached gingiva, the position of the mucogingival junction, and the height of the interdental papillae in the region where the OE was performed as well as in the adjacent region. Materials and Methods: This research included 28 adult patients (both orthodontically treated and untreated). The treated group included 15 patients, in whom orthodontic extrusion of the upper or lower frontal teeth was indicated and performed. The untreated group included 13 patients, with no previous or undergoing orthodontic treatment. Patients with periodontal disease and periodontal pockets in the frontal region and patients allergic to iodine were excluded from the study. Gingivomorphometric measurements were performed on two occasions in three groups of teeth (24 extruded and 30 agonist teeth in the treated patients; 66 teeth in the untreated patients). Statistical analysis of the obtained data was performed using the software package SPSS version 26.0. Results: Orthodontic extrusion induced changes in the position of the mucogingival line and an increase in the width of the keratinized gingiva. There were no statistically significant effects on the depth of the gingival sulcus, the attached gingiva width, or the height of the interdental papillae. Conclusions: Orthodontic tooth extrusion has an effect on the periodontium in the observed region. Vertical orthodontic force, directed towards the coronal plane, affects the surrounding soft oral tissues.


Subject(s)
Gingiva , Orthodontic Extrusion , Humans , Female , Adult , Male , Orthodontic Extrusion/methods , Keratins , Young Adult , Periodontal Ligament
3.
J Clin Periodontol ; 49(12): 1244-1252, 2022 12.
Article in English | MEDLINE | ID: mdl-35833531

ABSTRACT

AIM: Periodontal Ehlers-Danlos syndrome (pEDS) is a monogenic type of Ehlers-Danlos syndrome characterized by periodontal destruction at a young age. The present study aimed to document the oral phenotype of pEDS based on prospective clinical investigations. MATERIALS AND METHODS: Thirty-five adult individuals from 13 families with a clinically and genetically confirmed diagnosis of pEDS underwent a systematic oral assessment. RESULTS: Periodontitis stage 3 or 4 or edentulism due to periodontal destruction were diagnosed in 94% of the individuals. First permanent tooth loss was reported at the age of 21.5 years (median; range 13-43 years). Deep periodontal pockets were infrequent, with 94% measuring <4 mm. However, there was increased clinical attachment loss (CAL) averaging 8 mm (range 4-13 mm), and the probability of being edentate between the age of 35 and 44 years was 28-47% compared with less than 0.25% of the general population. Radiographic anomalous findings were only found in a portion of subjects and consisted of fused roots of maxillary second molars (81%), root hypoplasia (57%), taurodontism (26%) and tooth rotation of premolars (67%). As such, radiographic findings are not considered common characteristics of pEDS. CONCLUSIONS: Characteristic oral traits of pEDS in adults are severe CAL with shallow probing depths and marked gingival recession. This is complemented by a lack of attached gingiva. These indications need to be paralleled by genetic analyses to diagnose pEDS unambiguously.


Subject(s)
Ehlers-Danlos Syndrome , Gingival Recession , Periodontitis , Humans , Ehlers-Danlos Syndrome/complications , Prospective Studies , Gingival Recession/etiology , Bicuspid , Periodontal Attachment Loss
4.
Clin Oral Investig ; 26(1): 751-759, 2022 Jan.
Article in English | MEDLINE | ID: mdl-34783916

ABSTRACT

OBJECTIVES: The present study was performed to determine the gingival dimensions (width and thickness) among young individuals in a central Indian population. MATERIALS AND METHODS: Periodontal probing depth, width of the keratinized and attached gingiva, and gingival thickness were recorded on maxillary and mandibular teeth from central incisor to first molar unilaterally in 75 systemically healthy individuals (32 males and 43 females; 19-30 years of age). Comparisons were made gender-wise, arch-wise, tooth-wise, and site-wise using either the Student's t test or the ANOVA. RESULTS: Keratinized and attached gingiva were wider in the maxilla than in the mandible both at proximal and at mid-buccal aspects (p < 0.001). At the tooth level also, gingiva was wider at the maxillary teeth than the corresponding mandibular teeth and at proximal aspects than at the mid-buccal aspect (p < 0.001). Regarding the thickness, gingiva was thicker among males, in the mandible, and at inter-proximal sites (p < 0.001). In either arch, maximum thickness was observed at the incisor region and least at the canine region. CONCLUSIONS: Dimensions of the gingival tissues vary between different populations and between different areas of the dentition within the same subject. These variations need to be better understood because these aspects may have an important bearing on periodontal treatment planning as width and thickness of gingiva are important in terms of maintenance of periodontal health. CLINICAL RELEVANCE: The dimensions of the clinically healthy gingiva are important in clinical practice as they can influence the progression of periodontal disease as well as impact the outcome of periodontal and restorative and orthodontic therapy.


Subject(s)
Gingiva , Mandible , Cross-Sectional Studies , Female , Humans , Incisor , Male , Maxilla
5.
J Oral Implantol ; 48(1): S1-S8, 2022 Feb 01.
Article in English | MEDLINE | ID: mdl-34965296

ABSTRACT

The long-term functional success of implant treatment depends on the stability of the crestal bone around the implant platform. The esthetic result is achieved by adequate quality and quantity of soft tissue in the peri-implant area. The soft tissue creates the buffer area that ensures the mechanical and biological protection of the underlying bone. Therefore, it is necessary to maintain in the long term, not only implant osseointegration, but also the integrity of the soft tissue around the sub- and suprastructures of the implant restoration. To create the protective soft tissue area, it is necessary to ensure 3 criteria. This treatment approach will be defined as TWS-soft tissue management: T for thickness, W for width, and S for stability. There are many ways to achieve the first 2 criteria, which are described in the literature. Achieving the third criterion of stability has become possible only recently because of the development of digital treatment planning, surgically guided, and prosthetic-assisted technology that uses a 1-time abutment and its implementation into the dental practice. The purpose of this article is to present with clinical cases a detailed description of each criterion.


Subject(s)
Dental Implants , Esthetics, Dental , Gingiva/surgery , Osseointegration
6.
Genet Med ; 23(2): 316-322, 2021 02.
Article in English | MEDLINE | ID: mdl-33005042

ABSTRACT

PURPOSE: We report prospective clinical investigations of children affected with periodontal Ehlers-Danlos syndrome (pEDS). The main clinical features of pEDS in adults are early severe periodontitis, generalized lack of attached gingiva, and pretibial hemosiderin plaques due to dominant pathogenic variants in the C1R or C1S genes. METHODS: Nineteen children with a parent diagnosed with molecularly confirmed pEDS underwent physical examination including oral and radiological investigations followed by genetic testing. RESULTS: The only consistent manifestation of pEDS in childhood was a characteristic gingival phenotype: generalized lack of attached gingiva. All children with this gingival phenotype had inherited the familial pathogenic variant (n = 12) whereas the gingival phenotype was absent in children without the familial pathogenic variant (n = 7). Easy bruising was reported in eight affected and zero unaffected children. Other manifestations of pEDS were rarely present in children. Only 2/12 affected children aged 8 and 13 years fulfilled the clinical criteria for pEDS. CONCLUSION: Generalized lack of attached gingiva is a pathognomonic feature of pEDS and the only clinical finding that is consistently present in affected adults and children. This is important because an early diagnosis may facilitate better dental hygiene in childhood, which may be essential to prevent early dental loss.


Subject(s)
Ehlers-Danlos Syndrome , Periodontitis , Adult , Child , Ehlers-Danlos Syndrome/diagnosis , Ehlers-Danlos Syndrome/genetics , Gingiva , Humans , Phenotype , Prospective Studies
7.
Clin Oral Investig ; 25(8): 4967-4973, 2021 Aug.
Article in English | MEDLINE | ID: mdl-33515119

ABSTRACT

OBJECTIVES: The purpose of this study was to estimate the prevalence of thin and thick gingival phenotype (GPh) in a sample of Dominican subjects and correlate it with clinical parameters. MATERIALS AND METHODS: One-hundred seven periodontal healthy volunteers in the range of 18-73 years were enrolled in the study. GPh was defined by the transparency of a periodontal probe through the buccal gingival margin on the upper right or left central incisor. Clinical periodontal parameters such as keratinized gingiva width (WKG), attached gingiva width (WAG), probing depth (PD), plaque index (PI), and gingival index (GI) were recorded by a calibrated examiner. Frequency distribution of qualitative variables was calculated. For quantitative variables, Mann-Whitney and Kruskal-Wallis tests were used for comparison of groups. RESULTS: There was no association between GPh and sex. There were no significant differences between thin and thick GPh regarding age, PD, GI, and interproximal index. The association between tooth morphology and GPh was significant (p = 0.018). Median amount of keratinized gingiva was significantly larger (p = 0.01) in subjects with thin gingival phenotype (median = 6.00 mm) when compared with subjects with thick gingival phenotype (median = 5 mm). CONCLUSIONS: Subjects with thin GPh presented larger WKG. Furthermore, there was an association between tooth morphology and GPh. CLINICAL RELEVANCE: This is the first study to report the distribution of gingival phenotype and its relationship with different periodontal parameters of a Caribbean population. Our findings can contribute to the clinicians when planning or performing dental procedures.


Subject(s)
Gingiva , Tooth , Adult , Dental Plaque Index , Humans , Periodontal Index , Phenotype
8.
BMC Oral Health ; 21(1): 287, 2021 06 04.
Article in English | MEDLINE | ID: mdl-34088298

ABSTRACT

BACKGROUND: The anatomical features of the gingiva and the clinical crowns and their interrelation, especially in aesthetically and functionally demanding areas, are important in complex dental or implant-retained prosthetic rehabilitations. This observational cross-sectional study was designed to evaluate gender- and age-related differences in the width of attached gingiva (WAG), the clinical crown length (CCL), and their interrelation in the anterior teeth to determine the relationship between the pink and white aesthetics. METHODS: Eighty (54 females, 26 males) fully dentate Caucasian participants between the ages of 20 and 25 years and 36 probands (23 females, 13 males) between the ages of 45 and 55 years were included in the present study. The CCL of the maxillary and mandibular canines, as well as the central incisors of the maxilla and mandible, were determined with a dental sliding caliper measuring from the middle margin of the gingiva at its deepest point to the incisal edge. The clinical investigation of the WAG was performed by inserting a periodontal probe into the gingival sulcus in the middle of the buccal surface to firstly measure the probing pocket depth. The distance between the gingival margin and mucogingival junction (MGJ) was then measured with a Beerendonk sliding caliper in the middle of the labial curvature, and the clinical WAG was determined by subtraction of the measured probing depth. For the statistical analysis, the Mann-Whitney U test, the Wilcoxon-Test, the Spearman's rank correlation, and a two-factorial non-parametric analysis were used. RESULTS: There was no correlation between the CCL and the WAG in a healthy periodontium. Gender influenced the CCL, with men having significantly longer teeth than women in both maxilla (P ≤ 0.01) and mandible (P ≤ 0.05). Age did not influence the CCL significantly neither in the upper (P = 0.06) nor in the lower jaw (P = 0.33). Gender did not show to have a significant influence on the WAG of maxilla (P = 0.69) and mandible (P = 0.26). But differences in the WAG between young and old participants were observed in both upper (P ≤ 0.01) and lower jaw (P ≤ 0.05). CONCLUSION: The present observational study demonstrated that the mean values of cohorts with mixed age groups and genders should not be considered when attempting to determine the ideal relationships between the pink and white aesthetics since the statistical analyses showed significant differences between different age groups and genders.


Subject(s)
Gingiva , Incisor , Adult , Crowns , Esthetics, Dental , Female , Humans , Male , Maxilla , Odontometry , Young Adult
9.
Clin Oral Investig ; 23(7): 3033-3046, 2019 Jul.
Article in English | MEDLINE | ID: mdl-30430338

ABSTRACT

OBJECTIVE: This study assessed the impact of 10% hydrogen peroxide whitening strip exposure on the genotoxicity and oxidative damage by means of the buccal micronucleus cytome assay by counting nuclear abnormalities (NAs) in buccal mucosa and attached gingiva cells and by analyzing in whole saliva the molecule 8-hydroxy-2'-deoxyguanosine (8-OHdG). MATERIALS AND METHODS: The study was conducted on 113 subjects divided into two groups: group 1 or control (n = 53), non-whitening strip exposed, and group 2 (n = 60), whitening strip exposed (Crest® 3D Whitestrips® premium plus, 10% hydrogen peroxide). Oral epithelial cells and whole saliva samples were taken at the beginning and 30 days later for group 1 and immediately before bleaching and 15 and 30 days after the end of the bleaching for group 2. RESULTS: An increased frequency of NAs (p < 0.05) and higher levels of 8-OHdG (p < 0.05) were observed after bleaching exposure. Also, a positive correlation exists between oxidative stress produced by hydrogen peroxide and micronuclei was found. CONCLUSION: Individuals exposed to 10% hydrogen peroxide whitening strips exhibit NAs increased in oral epithelial cells and 8-OHdG in saliva, which is directed related to nuclear and oxidative DNA damage, respectively. CLINICAL SIGNIFICANCE: Hydrogen peroxide is the active agent of tooth whitening and this compound induced DNA damage. Individuals exposed to whitening strips with 10% hydrogen peroxide exhibit increased genotoxic and oxidative damage. Therefore, self-application of bleaching agents should be handled carefully since it could be a risk to human health.


Subject(s)
DNA Damage , Hydrogen Peroxide , Oxidants , Tooth Bleaching , DNA Damage/ethics , Female , Humans , Hydrogen Peroxide/toxicity , Male , Oxidants/toxicity , Oxidative Stress , Tooth Bleaching/adverse effects
10.
J Esthet Restor Dent ; 31(3): 240-245, 2019 05.
Article in English | MEDLINE | ID: mdl-30295994

ABSTRACT

OBJECTIVE: To noninvasively determine the relationship between the thickness of the buccal bone and attached gingiva of the maxillary premolars. MATERIAL AND METHODS: 128 maxillary premolars in 32 patients were assessed for measurement of buccal bone thickness and corresponding attached gingival thickness at 3 mm apical to cemento-enamel junction. Buccal bone thickness was measured on cone-beam computed tomography scans and attached gingival thickness by ultrasound unit. Pearson's correlation coefficient was calculated to assess the correlation between buccal bone and attached gingival thickness at each tooth type. RESULTS: The mean buccal bone thickness at the maxillary premolars was 1.07 mm. The 1st premolars had a buccal bone thickness < 1 mm at 68% of all sites, and the 2nd premolars had a buccal bone thickness of 1.0-2.0 mm at 32% of all sites. The 1st premolars had a gingival thickness > 1.2 mm at 55% of all sites, and the 2nd premolars had a gingival thickness of 1.1-1.3 mm at 45% of all sites. The correlation between buccal bone and attached gingival thickness was moderately positive (r = 0.406; P < .001). CONCLUSIONS: The relationship between buccal bone thickness and gingival thickness is independent of each other in the maxillary right first premolar, whereas a moderate correlation with a dependent relation exists in the maxillary right second premolar, maxillary left first premolar, and maxillary left second premolar. CLINICAL SIGNIFICANCE: Soft tissue and hard tissue associated with volumetric changes in maxillary premolar region can be unfavorable for both aesthetic and implant placement. In fact this study highlighted the relationship between the thickness of attached gingiva and corresponding buccal bone in maxillary premolar region so to enable for proper planning of implant therapy following extraction.


Subject(s)
Cone-Beam Computed Tomography , Gingiva , Bicuspid , Dental Arch , Humans , Maxilla , Tooth Cervix
11.
Gen Dent ; 66(1): 34-38, 2018.
Article in English | MEDLINE | ID: mdl-29303760

ABSTRACT

The frenum is a mucosal fold that attaches the lips or cheeks to the alveolar mucosa, gingiva, and underlying periosteum. Consequences of an abnormal frenal attachment include gingival recession, decreased vestibular depth, decreased range of lip movement, and involvement of interdental papilla, causing a diastema. Several methods to eliminate ectopic frenal attachments have been suggested, including frenectomy (elimination) and frenotomy (repositioning). This case report describes the use of a modified frenectomy technique in a 15-year-old girl with excess gingiva between the maxillary central incisors, which exhibited a 3-mm diastema. First, a semilunar primary incision was made in the palatal surface at a 5-mm distance from the tip of the papilla. Next, sulcular incisions were made around the tooth, and the papilla was transposed to the buccal via a papilla preservation flap. After complete elimination of frenal attachments in the bone, the flap was repositioned and sutured to the palatal surface. Afterward, the frenum was classically cut and sutured. Through this approach, the position of the frenum was changed apically without invading the papilla. At the 3-month follow-up, it was found that the modified technique (combination of papilla preservation flap and frenotomy) had minimized the surgical scar on the buccal surface, preserved the papilla, and yielded optimal esthetic results.


Subject(s)
Labial Frenum/surgery , Adolescent , Female , Gingiva/abnormalities , Gingiva/surgery , Humans
12.
Clin Oral Investig ; 21(4): 1103-1111, 2017 May.
Article in English | MEDLINE | ID: mdl-27306889

ABSTRACT

OBJECTIVES: Attached peri-implant gingiva has proven to have an influence on the long-term stability of dental implants. In patients with head and neck cancer, a functional peri-implant gingiva is even more of critical importance. The aim of the presented prospective study was to investigate a three-dimensional xenogeneic collagen matrix for augmentation around dental implants in patients with former head and neck cancer. MATERIAL AND METHODS: Eight patients presenting with insufficient peri-implant gingiva underwent vestibuloplasty on 51 implants using a xenogeneic collagen matrix. The clinical performance and the shrinking tendency of the matrix were analyzed in a cohort study. Furthermore, eight biopsies from the augmented regions were examined histologically to determine the biomaterial-related tissue reaction. RESULTS: Initially after vestibuloplasty, a mean width of attached gingiva of 4.4 ± 0.94 mm could be achieved. At clinical follow up investigation 6 months after vestibuloplasty, a mean width of 3.9 ± 0.65 mm attached peri-implant gingiva with a mean shrinking tendency of 14 % could be detected. Histological analysis of the biopsies revealed a well integrated collagen22 matrix covered with epithelium. Within the compact layer, mononuclear cells were observed only, while the spongious layer was infiltrated with a cell-rich connective tissue. CONCLUSION: Within its limits, the presented study revealed that the investigated collagen matrix is suitable to enlarge the peri-implant attached gingiva in head and neck cancer patients without adverse reactions or a multinucleated giant cell-triggered tissue reaction. CLINICAL RELEVANCE: The application of the investigated three-dimensional collagen matrix in vestibuloplasty achieved a sufficient amount of peri-implant attached gingiva in head and neck cancer patients. The favorable tissue reaction and the low shrinking tendency make the collagen matrix a promising alternative to autologous tissue grafts.


Subject(s)
Collagen/therapeutic use , Dental Implants , Gingiva/pathology , Gingiva/surgery , Head and Neck Neoplasms/pathology , Vestibuloplasty/methods , Aged , Female , Germany , Humans , Male , Middle Aged , Prospective Studies
13.
Clin Oral Investig ; 21(2): 505-518, 2017 Mar.
Article in English | MEDLINE | ID: mdl-28108833

ABSTRACT

OBJECTIVES: The present systematic review compared the effectiveness of soft tissue substitutes (STSs) and autogenous free gingival grafts (FGGs) in non-root-coverage procedures to increase keratinized tissue (KT) width around teeth. MATERIALS AND METHODS: Included studies fulfilled the following main eligibility criteria: (a) preclinical in vivo or human controlled trials using FGG as control, (b) non-root-coverage procedures, and (c) assessment of KT width. Meta-analysis was performed on the gain in KT width (primary outcome variable) and several secondary variables. RESULTS: Eight human trials with short observation time evaluating five different STSs were identified. FGG yielded consistently significantly (p < 0.001) larger increase in KT width irrespective whether the comparison regarded an acellular matrix or a tissue-engineered STS. Further, FGG yielded consistently ≥2 mm KT width postoperatively, while use of STS did not, in the few studies reporting on this outcome. On the other hand, STSs resulted in significantly better aesthetic outcomes and received greater patient preference (p < 0.001). CONCLUSIONS: Based on relatively limited evidence, in non-root-coverage procedures, FGG (1) resulted consistently in significantly larger increase in KT width compared to STS and (2) yielded consistently ≥2 mm KT width postoperatively, while STSs did not. STSs yielded significantly better aesthetic outcomes, received greater patient preference, and appeared safe. CLINICAL RELEVANCE: Larger and more predictable increase in KT width is achieved with FGG, but STSs may be considered when aesthetics is important. Clinical studies reporting relevant posttreatment outcomes, e.g., postop KT width ≥2 mm, on the long-term (>6 months) are warranted.


Subject(s)
Connective Tissue/transplantation , Esthetics, Dental , Gingiva/transplantation , Gingival Recession/surgery , Gingivoplasty/methods , Humans , Surgical Flaps
14.
Clin Oral Implants Res ; 26(8): 865-869, 2015 Aug.
Article in English | MEDLINE | ID: mdl-24580810

ABSTRACT

OBJECTIVES: To evaluate a possible relationship between gingival biotypes and gingival thickness, papilla height and gingival width. MATERIAL AND METHODS: Thirty-six adult subjects were stratified by their gingival biotype (GB), as defined by transparency of a periodontal probe through the buccal gingival margin, into "thin" (18 subjects) and "thick" (18 subjects) GB. Out of these, extreme cases (6 "very thin", 6 "very thick") were identified. Four different parameters were assessed: gingival thickness (GT), papilla height (PH), probing depth (PD) and gingival width (GW). RESULTS: When comparing "thin" and "thick" GB, midfacial GT (0.40 ± 0.07 vs. 0.72 ± 0.11 mm; P < 0.0001), PH (3.76 ± 0.50 vs. 3.95 ± 0.41 mm, P = 0.02) and GW (3.01 ± 1.26 vs. 4.63 ± 0.86 mm, P = 0.04) were lower in the "thin" GB group. Further stratification into moderately and extremely "thin"/"thick" GB eliminated the differences between the moderate groups. CONCLUSION: Our data support the traditional hypothesis that two different gingival biotypes with concomitant properties distinguishable by gingival transparency exist. In addition, we provide evidence that an alternative classification into "very thick", "moderate" and "very thin" biotypes might be advantageous, because the unique properties were seemingly primarily driven by subjects with extreme values.


Subject(s)
Gingiva/anatomy & histology , Adult , Cross-Sectional Studies , Female , Humans , Male , Odontometry , White People
15.
Cureus ; 16(3): e56077, 2024 Mar.
Article in English | MEDLINE | ID: mdl-38618314

ABSTRACT

Proliferative verrucous leukoplakia (PVL) is an oral mucosa lesion with a high rate of malignant transformation. The diagnosis is often difficult, especially when the initial lesion is a simple homogeneous white leukoplakia, and when located only on the gingiva or palate. Moreover, the anatomopathological analysis is non-specific in the initial stages. The gingival PVL localisation (gPVL) is described as the most aggressive form with the highest rate of malignant transformation. Cases with a unique gingival localisation are rare, described with a "ring around the collar" clinical form. Considering the difficulty of early diagnosis of gPVL, we report the case of a 72-year-old woman, who presented "white lesions on her gingiva" with a slight discomfort in February 2019. The lesion was initially limited to the buccal part of the mandibular right gingiva, but rapidly extended to all the lingual and buccal mandibular gingiva during follow-up, leading to a diagnosis of gPVL. Two biopsies were performed, which concluded a verrucous hyperplasia and papilloma with a lichenoid part. The diagnosis of gPVL was made after a six-month follow-up based on clinical and anatomopathological factors. The gPVL transformed into a squamous cell carcinoma (SCC) after 18 months of follow-up. A surgical right mandibular bone excision with an autologous left fibula graft associated with radiotherapy was performed. Three years after the surgery, the patient remains under monitoring, with several gPVL and SCC recurrences treated. This case highlights that gPVL is a rare and aggressive form of PVL, with a high risk of fast malignant transformation. Knowledge about its aetiology, anatomic pathology, and biological markers is highly needed to speed up the diagnosis and develop specific follow-up and treatment.

16.
Gen Dent ; 61(5): 56-9, 2013 Aug.
Article in English | MEDLINE | ID: mdl-23928441

ABSTRACT

The maxillary labial frenum is a normal anatomical structure in the oral cavity. An abnormal labial frenum causes localized gingival recession and midline diastema, both of which can interfere with oral hygiene procedures, and eventually affect esthetics. When the frenum maintains its high papillary attachment, frenectomy is the treatment of choice. Though this technique has undergone many modifications, the zone of attachment and esthetics in the anterior maxillary region have been neglected. This article highlights a new frenectomy technique that results in good esthetics, excellent color match, gain in attached gingiva, and healing by primary intention at the site of thick, extensive abnormal frena.


Subject(s)
Esthetics, Dental , Labial Frenum/surgery , Adult , Color , Diastema/etiology , Female , Follow-Up Studies , Gingiva/surgery , Gingival Recession/etiology , Humans , Hypertrophy , Labial Frenum/pathology , Lip/surgery , Male , Patient Care Planning , Periosteum/surgery , Surgical Flaps/surgery , Wound Healing/physiology
17.
Clin Exp Dent Res ; 9(1): 36-44, 2023 02.
Article in English | MEDLINE | ID: mdl-36424485

ABSTRACT

OBJECTIVES: One of the simplest methods to increase keratinized gingiva is the modified apically repositioned flap (MARF) technique. In this method, the periosteum remains exposed, which may lead to postoperative pain and discomfort. In the presence of bone dehiscence, bone resorption and gingival recession may occur. Hence, this study aims to use platelet-rich fibrin (PRF) to promote wound healing in the MARF technique and overcome its disadvantages. MATERIAL AND METHODS: In this randomized controlled trial study, 10 patients (six males and four females with a mean age of 33.9 ± 11.13) with less than 2 mm of attached gingiva bilaterally were treated by the MARF + PRF membrane (test group), on the one hand, whereas, on the other hand, it was treated only by MARF (control group). Clinical parameters of keratinized gingiva include thickness, width, and vestibule depth before and 8 weeks after the intervention were measured. RESULTS: The attached gingival width increased significantly in both groups (1.7 mm in the MARF and 2.3 mm in the PRF) and this was greater in the PRF group (p < .05). Gingival thickness in the PRF method was significantly higher than in the control group (p < .05). Probe depth, vestibular depth, and postoperative pain were not different in both groups. Wound shrinkage in the MARF group (51%) was significantly higher than in the PRF group (30%) (p < .05). CONCLUSION: Using PRF with the MARF method significantly increased the width and thickness of the gingiva and reduced shrinkage compared to MARF only. Postoperative pain and vestibular depth changes were similar in both groups.


Subject(s)
Gingival Recession , Platelet-Rich Fibrin , Male , Female , Humans , Young Adult , Adult , Middle Aged , Gingiva/surgery , Gingival Recession/surgery , Face , Pain, Postoperative/etiology , Pain, Postoperative/prevention & control
18.
Prog Orthod ; 24(1): 17, 2023 Jun 26.
Article in English | MEDLINE | ID: mdl-37357250

ABSTRACT

BACKGROUND: Central incisor impaction is a rare condition with potentially severe clinical and psychological implications for the patient. Treatment techniques vary according to the pretreatment situation and individual factors. The aim of this study was to compare the esthetic outcomes and treatment times between two different approaches. MATERIALS AND METHODS: In this retrospective study, thirty-one consecutive patients (13 boys, 18 girls; average age 9.5 ± 2.3 years) with a total of 34 impacted permanent upper central incisors were included in the study. Patients were divided into two groups according to method of treatment. Group A comprised patients in whom spontaneous eruption occurred after space opening (n = 12), and Group B comprised patients in whom teeth showed no eruption and required treatment with a modified closed eruption method with palatally oriented traction (n = 19). Treatment time and esthetic outcomes were assessed and compared between groups. RESULTS: The mean treatment time was 22.0 ± 6.7 months, and all teeth were successfully aligned. No statistically significant difference in average treatment time was found between groups in baseline characteristics (p > 0.05). The amount of attached gingiva was significantly smaller when compared to contralateral reference teeth in the closed eruption group (Group B; p = 0.03). However, no difference in amount of attached gingiva was found between both groups (p = 0.26). Additionally, no difference in the clinical crown length was found between groups (p = 0.27). CONCLUSION: The closed eruption method with palatal traction directed at the peak of the alveolar crest provided results comparable to the physiologic tooth eruption.


Subject(s)
Tooth Eruption , Tooth, Impacted , Male , Female , Humans , Child , Incisor , Traction , Retrospective Studies , Maxilla , Tooth, Impacted/therapy
19.
Folia Med (Plovdiv) ; 65(3): 468-475, 2023 Jun 30.
Article in English | MEDLINE | ID: mdl-38351824

ABSTRACT

AIM: The aims of the present study were to explore the relations between the gingival phenotype (GP) and the periodontal health status and find the prevalence of a specific gingival phenotype in a small Bulgarian population.


Subject(s)
Gingiva , Periodontal Diseases , Humans , Periodontal Diseases/epidemiology , Phenotype , Prevalence
20.
Cureus ; 15(7): e42086, 2023 Jul.
Article in English | MEDLINE | ID: mdl-37602047

ABSTRACT

INTRODUCTION: Gingival shade matching, often overlooked, plays an integral role in designing prostheses for patients with high smile lines, gingival defects, and cases where the acrylic flange of removable dentures extends into the aesthetic zone. The purpose of this study was to find the most prevalent gingival shade in a sample of the South Indian population. MATERIALS AND METHODS:  A total of 110 participants were included in the study based on the inclusion and exclusion criteria. The standard daylight method of shade matching was used for this study. The participants were seated in a dental chair in the vertical position with their heads supported, their mouths open, and cheek retractors in place. The study area, gingiva, and vestibular region in relation to maxillary and mandibular right central incisors were dried with a three-way syringe, 15cm away, for 3 seconds before shade matching for 5 seconds at each reference point with an Ivoclar Vivadent IPS Dsign shade guide. CONCLUSION: The most prevalent shade in the marginal and vestibular regions of the gingiva of the South Indian population was found to be GM2 shade, while the most prevalent shade of the attached gingiva was found to be G2 shade. A good percentage of the attached gingival shade was not matched with the tabs available in this shade guide.

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