Immediate implant placement with immediate or delayed provisionalization in the maxillary aesthetic zone: A 10-year randomized trial.

AIM: To compare the marginal bone level of immediately placed implants, with either immediate or delayed provisionalization (IP or DP), in the maxillary aesthetic zone after 10 years of function. MATERIALS AND METHODS: Participants with a failing tooth in the maxillary aesthetic zone were randomly assigned to immediate implant placement with either IP (n = 20) or DP (n = 20) after primary wound closure with a free gingival graft. The final restoration was placed 3 months after provisionalization. The primary outcome was change in marginal bone level. In addition, implant survival, restoration survival and success, peri-implant tissue health, mucosa levels, aesthetic indices, buccal bone thickness and patient satisfaction were evaluated. RESULTS: After 10 years, the mean mesial and distal changes in marginal bone level were -0.47 ± 0.45 mm and -0.49 ± 0.52 mm in the IP group and -0.58 ± 0.76 mm and -0.41 ± 0.72 mm in the DP group (p = .61; p = .71). The survival rate was 100% for the implants; for the restorations, it was 88.9% in the IP group and 87.5% in the DP group. Restoration success, according to modified USPHS criteria, was 77.8% in the IP group and 75.0% in the DP group. The prevalence of peri-implant mucositis was 38.9% and 35.7% and of peri-implantitis 0.0% and 6.3%, respectively, in the IP group and DP group (p = 1.0; p = .40). The Pink Esthetic Score and White Esthetic Score was 15.28 ± 2.32 in the IP group and 14.64 ± 2.74 in the DP group, both clinically acceptable (p = .48). The buccal bone thickness was lower in the DP group. Patient satisfaction was similar in both groups (p = .75). CONCLUSIONS: The mean marginal bone level changes after immediate implant placement with IP were similar to those after immediate placement with DP. CLINICAL TRIAL REGISTRATION: Registered in the National Trial Register (NL9340).

Timing implant provisionalization: Decision-making and systematic workflow.

OBJECTIVE: Provisionalization is an important step to achieve esthetic results in implant cases, and many different techniques for provisional restoration fabrication have been described. However, depending on the clinical scenario, the provisionalization strategy will require different approaches and timing. The clinician should modify the provisional restorations efficiently to reduce the number of disconnections from the implant, as repeated disconnections may have biological consequences. This article aims to schematize different scenarios requiring implant provisionalization and propose strategies to help the clinician condition the peri-implant tissues, respecting perio-prosthodontic fundamentals for soft tissue, biological, and esthetic stability. CLINICAL CONSIDERATIONS: The clinical outcomes of modern implant therapy aim to achieve results that emulate natural dentition. Different scenarios may require adjunct therapy, including hard- and soft-tissue grafting, which complicates treatment. The provisionalization strategy will vary depending on the initial condition of the tissues, the need for reconstructive procedures, and the timing of implant placement. Selecting the right strategy based on the case type is necessary to reduce treatment time and complications associated with inadequate prosthetic handling of the soft tissues. CLINICAL SIGNIFICANCE: Proper emergence profile conditioning through provisional restorations will allow for biologically sound and esthetically pleasing outcomes in implant restorations.

Fiber-Reinforced Hybrid Prosthesis Veneered With Composite Resin for 4 Implant-Supported Fixed Provisional and Definitive Restorations.

This technical note describes the fabrication and benefits of fiberglass-reinforced hybrid prosthesis veneered with composite resin for 4 implant-supported fixed professional and final restorations. The described prosthesis reduces rehabilitation time, minimizes impression problems, and ensures a passive fit of professional restoration. The prosthesis provides immediate rehabilitation of 4 implants with ease of adjustments and repair during the entire provisional phase. Moreover, it can be easily converted to final restoration with minimal modifications, excellent esthetic results, and reduced costs.

Comparison of Fracture Resistance between Implant-supported Bis-acryl Interim 3-unit FDPs Using Six Different Strengthening Mechanisms: An In Vitro Study.

AIM: To investigate six different strengthening mechanisms for three-unit implant-supported provisional restorations. MATERIALS AND METHODS: Six techniques of provisional fixed prostheses (PFP) reinforcement were investigated and were assigned to different groups (n = 10): group (ZP) zirconia powder, group (SK8) silk thread wrapped as a figure-of-8 pattern around middle third of abutment, group (RC8) size 00 retraction cord wrapped as a figure-of-8 pattern around middle third of abutment, group (RF8) Resin impregnated glass fiber ribbon wrapped as a figure-of-8 pattern around abutment, group (KV8) Kevlar 29 cord wrapped as a figure-of-8 pattern around middle third of abutment, group (KV) Kevlar 29 strands incorporated in resin mix. Compared against unenforced bis-acryl as control group (CL). Seventy Metal Dies were 3D printed having Soft Tissue Gingiva Mask. Using a custom-made silicone Index, 70 PFP were fabricated (10 of each group) and were cemented to their corresponding metal dies using zinc polycarboxylate cement. All specimens were thermal cycled for 1000 cycles using order of 20 seconds at 55°C and 20 seconds at 5°C with 10 seconds transport. Fracture resistance test was done using universal testing machine. All specimens were loaded to failure. Data were collected, tabulated and statistically analyzed. RESULTS: Kolmogorov-Smirnov normality test showed no significant difference between data in each group. So, data are normally distributed in each group. Descriptive statistics showed higher mean values of CL group (780.8 ± 164) followed by RF8 group (614.2 ± 158.2), followed by RC8 group (550.2 ± 339.2), followed by KV8 group (442.1 ± 198.4), followed by KV group (403.9 ± 306), followed by SK8 group (175.9 ± 90.8), and finally ZP group (136.5 ± 135.7). One-way ANOVA revealed significant difference between the tested groups (p = 0.036). CONCLUSION: Bis-acryl provisional restorations had better mean fracture resistance values than all other strengthening mechanisms. Bis-acryl provisional restorations did not gain more strength by any of the added materials. One-way ANOVA revealed significant difference between all tested groups. CLINICAL SIGNIFICANCE: Provisional restorations over implant should be strong enough to serve for the long period of bone and tissue healing. Current materials alone cannot survive for long. It serves as temporization between steps of fixed restorations construction. How to cite this article: Rayyan M, Sayed M, Hujeiry AM et al. Comparison of Fracture Resistance between Implant-supported Bis-acryl Interim 3-unit FDPs Using Six Different Strengthening Mechanisms: An In Vitro Study. J Contemp Dent Pract 2023;24(11):840-846.

A digital workflow for accurately and rapidly creating an immediate provisional restoration with natural emergence profile using extracted tooth.

To describe a digital workflow for creating a provisional restoration by using an extracted tooth rapidly, finally fixing the provisional restoration in the targeted position precisely and preserving the natural emergence profile from the time of provisional restoration to final restoration. CLINICAL CONSIDERATIONS: The use of extracted tooth as an immediate provisional restoration is an effective method for preserving the shape of the emergence profile. However, the existing methods for creating a provisional restoration by using natural tooth are time-consuming and there is no reliable method to precisely attach tooth to temporary abutment. This case demonstrates a new method for using patient's natural tooth as an immediate provisional restoration under a sequence of guides, which significantly reduces the chair-side time and inconvenience for clinicians and patients. Immediate provisional restoration contributes to preserving the soft tissue architecture after post-extraction implant placement, especially when using the patient's tooth as a provisional restoration. Digital technology can help to improve the chair-side clinical efficiency of dentist. CLINICAL SIGNIFICANCE: Maintaining the natural soft tissue architecture is a huge challenge in dental implantology. Use of the extracted tooth as a provisional restoration is likely to achieve an optimal outcome. And digital technology is helpful to the efficiency and accuracy of treatment.

Effects of resin materials dedicated for additive manufacturing of temporary dental restorations on human gingival keratinocytes.

OBJECTIVE: This study investigated the effect of eluates of conventional and 3D-printed resin materials for manufacturing temporary dental restorations on gingival keratinocytes. METHODS: Three-dimensional (3D)-printed resin materials: 3Delta temp (Deltamed), NextDent MFH (Nextdent), Freeprint temp (Detax), GC temp (GC), were compared to Grandio disc (Voco) and Luxatemp (DMG). Human gingival keratinocytes (IHGKs) were exposed to eluates of the materials and XTT assays were performed at 24 h, 48 h, 72 h, or 144 h. For quantification of the proinflammatory response, the protein amount of IL-6 and 8 was determined in the supernatants using ELISA. One-way ANOVA with post hoc analysis was used to compare differences in cell viability and IL-6 and IL-8 levels between groups. RESULTS: At 24 h, and more remarkably at 48 h, a significant decrease in cell viability occurred for the 3D-printed materials compared to the untreated IHGKs, but also compared to Grandio disc and Luxatemp. Except for the expression of IL-8 in presence of the eluate of Grandio disc at 24 and 48 h, all tested materials caused attenuation of IL-6 and 8 from IHGKs for any observation period. CONCLUSIONS: The materials for additive manufacturing affect cell proliferation differently than the subtractive manufactured material Grandio disc and the conventional material Luxatemp. CLINICAL SIGNIFICANCE: In comparison to conventional and subtractive manufactured restorations, 3D printed temporary restorations might induce more negative effects on the gingival and probably also on pulpal health since viability and the proinflammatory response of oral keratinocytes are more intensively affected by these materials.

The biotransfer approach: The use of an alveolar cast die for the fabrication of the emergence profile on implant-supported interim restorations.

Maintaining natural-looking soft tissues around dental implants is one of the biggest challenges for the restorative team. To achieve this, the emergence profile of the preexisting teeth in the alveolus can be emulated rather than conditioning the soft tissue architecture arbitrarily. The biotransfer technique uses an interim restoration with a biologically driven emergence profile fabricated before the implant surgery.

Tooth and temporary filling material fractures caused by Cavit, Cavit W and Coltosol F: an in vitro study.

BACKGROUND: Tooth fractures can occur after temporary inter-appointment endodontic filling, resulting in not preserving and thus extraction of the affected tooth. The purpose of this investigation was therefore to evaluate the tooth substance fracture potential given by the expansion of endodontic temporary filling materials. METHODS: Tooth and access cavities were prepared in 80 mandibular molars. Four groups of 20 teeth each (Cavit, Cavit W and Coltosol F and control) were included. To simulate a clinical situation, the teeth were endodontically pre-treated and a calcium hydroxide dressing was placed. The cavities were filled with the corresponding temporary filling material, with exception of the control group, and kept submerged in distilled water for 15 days. The teeth were examined every 24 h by two calibrated observers under a stereomicroscope (7.5×), fractures of the temporary filling material and tooth structure were photo-documented, and the results statistically analyzed. Kaplan-Meier survival analysis were calculated to illustrate (survival = no fracture) probabilities to evaluate the time when the temporary filling material, tooth structure or both together occurred. Log-rank test was performed in order to assess significant differences between the materials and the subgroups used. RESULTS: Fractures were observed only in the Coltosol F group (p < 0.01), at the end of the observation period, a total of 13 teeth (65%) showed temporary filling material and eight teeth (40%) showed tooth structure fractures. No fractures in the pulp chamber area were observed at the end of the observation period in any group. CONCLUSIONS: Within the limitations of the current in vitro study, the results obtained suggest that tooth structure fractures caused by a temporary filling material can occur during endodontic treatment, thus compromising the success of the treatment.

Effect of Three Different Cooling and Insulation Techniques on Pulp Chamber Temperature during Direct Temporization with Polymethyl methacrylate-based Resin.

AIM AND OBJECTIVE: This in vitro study evaluates and compares the changes in pulp chamber temperature during direct fabrication of provisional restorations in maxillary central incisors after using three different cooling techniques. MATERIALS AND METHODS: Total of 60 samples of maxillary central incisors along with their putty indices were divided into four groups (one control and three experimental) and were prepared using a surveyor cum milling machine. Teeth were sectioned 2 mm below cementoenamel junction and a K-type thermocouple wire was inserted in the tooth and secured at the pulpal roof using amalgam. Putty index filled with DPI tooth molding resin material [polymethyl methacrylate (PMMA)] was placed on the tooth and temperature changes per 5 seconds were recorded by temperature indicating device for the control, on-off, precooled putty, and dentin bonding agent (DBA) group. RESULTS: The highest mean obtained was of the control (11.04°C), followed by DBA group (9.53°C), precooled putty group (6.67°C), and on-off group (1.94°C). Precooled putty index group took maximum time to reach the baseline temperature (847.5 seconds). CONCLUSION: On-off technique is the most effective method to reduce the intrapulpal temperature during polymerization, as compared to the other techniques used in the study. Retardation in the polymerization process was seen in precooled putty group, which may make this technique clinically inadvisable. CLINICAL SIGNIFICANCE: Thermal protection of pulp must always be considered during direct fabrication of provisional restoration when a PMMA-based resin is used. By using on-off technique, not only the thermal insult to the pulp can be effectively minimized but also the harmful effects of residual monomer (poor marginal fit and pulpal irritation) can be eliminated.

Evaluation of the effect of various beverages on the color stability and microhardness of restorative materials.

OBJECTIVE: The aim of this in-vitro study was to investigate the effects of frequently consumed beverages on the color stability and microhardness of various restorative materials. MATERIALS AND METHODS: Twenty-four samples were prepared in each group to examine the effect of different beverages on coloration and surface hardness of two direct composite resins (Filtek Z250, Filtek Z550); one indirect composite resin (Solidex); and one high viscosity glass ionomer cement (Equia Forte Fil). Samples were stored in four solutions (distilled water, black tea, coffee, and cola) at room temperature for 1 week (n = 6). The color values are taken at the beginning and the color and microhardness values taken at the end of 1 week were evaluated by the Kruskal-Wallis and Mann-Whitney U tests. RESULTS: The highest color change was observed in the Equia Fil, while the least color change was observed in the Z550 group. The highest degree of color change was observed in coffee and cola groups. While the lowest values of hardness were observed in the Solidex group, the highest values of hardness were observed in the Z550 group. The highest levels of hardness change were detected in the coffee and cola groups. CONCLUSION: The color and hardness of restorative materials can be negatively affected by consumed beverages. Nanohybrid composite resins are resistant to external coloration and hardness change.

PEKK-made indirect temporary crowns and bridges: a clinical pilot study.

OBJECTIVES: The aim of the present study was to find out whether the high-performance polymer PEKK is an equivalent alternative compared to cobalt chrome (CoCr)-made restorations, regarding to biocompatibility, stability, and comfort. MATERIALS AND METHODS: Twenty-two patients (m, 10; f, 12) who were indicated for a long-term temporary-fixed restoration were included. They were randomized through a lottery procedure into two groups: the first group was restored with veneered PEKK-made crowns and bridges (Pekkton ivory), while the second group was restored with veneered CoCr crowns. Clinical parameters (plaque index (PI), probing depth (PD), fracture, and chipping) were documented in a period of 3-5 months from the insertion of restoration. Furthermore, every patient completed the OHIP-14 questionnaire. An exchange of the restorations from the first to the alternative material was performed after a period of 3-5 months. RESULTS: All patients showed an improvement of the oral hygiene and probing depth after insertion of the temporary restorations. However, there were no significant differences between PEKK and CoCr-made restorations (P > 0.05). There was no chipping after 5 months for both kinds of materials. There was a noticeable reduction of pain and discomfort of patients after insertion of temporary restorations. However, there were no significant differences between the two materials (P > 0.05). CONCLUSIONS: PEKK-made temporary restorations offer a good and stable alternative to CoCr-made restorations. They have a high aesthetical advantage over CoCr restoration. CLINICAL RELEVANCE: Esthetic and price-efficient temporary crowns can be offered for the patient during periodontal therapy to improve its success, in particular by improving the oral hygiene.

Use of extracted anterior teeth as provisional restorations and surgical guide for immediate multiple implant placement: A clinical case report.

OBJECTIVE: The aim of this article is to describe the use of natural anterior teeth as a surgical guide to implant placement and provisional restoration for a young patient with root resorption of upper central incisors and left-lateral incisor. CLINICAL CONSIDERATIONS: Achieving soft tissue esthetics is quite a challenge in implant dentistry. Here, a case of immediate implant placement using the natural teeth of the patient as an immediate provisional restoration, which achieves satisfactory results in terms of soft tissue architecture. CONCLUSIONS: Post-extraction implant placement in combination with immediate loading of dental implants has been evolving into an appropriate procedure for the treatment of partially edentulous anterior maxilla. Different techniques that include use of the own teeth as provisional implant supported restoration helps to maintain architecture of gingival contour, specially papilla. CLINICAL SIGNIFICANCE: Natural architecture of anterior soft tissue is a big challenge in implant dentistry. Use of natural teeth as a surgical guide and provisional restorations might be helpful to obtain an optimal outcome.

Effects of modifying implant screw access channels on the amount of extruded excess cement and retention of cement-retained implant-supported dental prostheses: A systematic review.

STATEMENT OF PROBLEM: Cement-retained implant-supported prostheses eliminate screw loosening and enhance esthetics. However, retrievability and the possibility of removing extruded excess cement (EEC) have been problematic. PURPOSE: The purpose of this systematic review was to analyze the effects of modifying the screw access channel (SAC) on the amount of EEC and the retention of cement-retained implant-supported prostheses. MATERIAL AND METHODS: PubMed, Web of Science, Scopus, and Google Scholar databases were searched with appropriate key words. Related titles and abstracts published up to June 2017 were screened and selected on the basis of defined inclusion criteria. Full texts of all studies were read and subjected to quality assessments. After the initial search, 1521 articles were included in the study. Of these, 11 studies were subjected to critical appraisal, and 10 of them were reliable enough in methodology to be systemically reviewed. RESULTS: All the studies were in vitro and described a total of 260 specimens. According to the interpreted results, closed SACs caused lower retention with a higher amount of EEC, whereas open SACs caused the reverse. Also, as the abutment height decreased, retention decreased. CONCLUSIONS: Extending the crown's margin into the SAC, leaving the SAC open, and using internal vents in the SAC space are possible methods of modifying the SAC to gain higher retentive values. Also, the use of internal vents in the SAC system and open or partially filled SAC space reduce the amount of EEC.

Digital workflow to provide an immediate interim restoration after single-implant placement by using a surgical guide and a matrix-positioning device.

This article describes a workflow based on a top-down approach to provide a fixed-type immediate interim restoration after placing a single implant using a digitally driven surgical guide and a matrix-positioning device. A characteristic of the technique is that both the surgical guide and the matrix-positioning device are fabricated from a single diagnostic virtual trial restoration designed on computer-aided design (CAD) software. This workflow may shorten the time required for chairside placement of an interim restoration and enhance esthetics when rehabilitating anterior teeth.

Treatment of peri-implant recession with a screw-retained, interim implant restoration: A clinical report.

This clinical report describes a patient with an osseointegrated implant and definitive restoration of the maxillary right lateral incisor who was seeking resolution of the recession of the peri-implant tissues which revealed the underlying zirconia abutment. The patient had previously received a connective tissue graft in an unsuccessful attempt to resolve the recession. An undercontoured interim restoration that allowed for soft tissue coronal migration resolved the soft tissue deficiency.

Implant Digital Impression in the Esthetic Area.

The aim of this report is to describe two standardized protocols for digital impression when implant support rehabilitation is used in the esthetic area. The two techniques were used to transfer all provisional crown parameters to definitive restorations in different clinical scenarios. In the direct technique, an impression (STL1) is made of the provisional restorations attached to the implants, with surrounding gingival tissue. The second scan (STL2) captures the sulcular aspect of the peri-implant soft tissue immediately after removal of the provisional restoration. The last impression (STL3) of the complete arch is made with a standardized scanbody attached to the implant to capture the 3D location of the implant. The direct technique is indicated when the peri-implant soft tissues are stable upon removal of the provisional restoration. The indirect technique is used when the gingival tissue collapses rapidly after the removal of the provisional crown. The impressions of the provisional restoration and the position of the implant are similar to those obtained with the direct technique, and the shape of the peri-implant tissue is extrapolated from the negative shape obtained from making the digital impression when the provisional restoration is taken out of the mouth. Finally, in both techniques the 3 scans are superimposed to obtain a file, which contains the details of the peri-implant soft tissue. The direct and indirect digital techniques allowed realization of a predictable definitive restoration in the esthetic zone in different clinical scenarios, reducing the duration of clinical procedures.

Effect of Dentin Bonding Agent on Intrapulpal Temperature during Fabrication of Provisional Restorations by a Direct Method: An In Vitro Study.

AIM: To determine the effect of three different provisional restorative materials (PRMs) and application of dentin bonding agent (DBA) on intrapulpal temperature rise during fabrication of provisional crowns using a direct method. MATERIALS AND METHODS: Three PRMs-polymethyl methacrylate resin (PMMA), bis-acrylic resin, and dimethyl methacrylate resin (DMMA)-were used in the study. Dentin bonding agent (Single Bond 2, 3M ESPE, Germany) was applied in a single layer or double layer as an insulating material. A total of 45 molars were prepared for complete coverage restoration with chamfer finish line and 1.5 mm axial and 2 mm occlusal reduction. After application of a single or double layer of DBA, provisional materials were polymerized according to the manufacturer's instructions. The temperature increase inside the pulp chamber was measured with a T-type thermocouple wire. The readings were averaged for each group to determine the mean value of temperature rise. RESULTS: Statistical analysis was performed with analysis of variance (ANOVA) followed by post hoc Tukey test (a = 0.05). The temperature rise varied according to the provisional restoration material used (PMMA > DMMA > bis-acrylic resin) (p < 0.001) and the single or double layer of DBA (p < 0.001). Polymethyl methacrylate resin produced a higher intrapulpal temperature. CONCLUSION: Application of a double layer of DBA resulted in a significantly lower intrapulpal temperature.

Crown lengthening and restorative procedures in the esthetic zone.

Crown lengthening is one of the most common surgical procedures in periodontal practice. Its indications include subgingival caries, crown or root fractures, altered passive eruption, cervical root resorption and short clinical abutment, and its aim is to re-establish the biologic width in a more apical position. While the procedure in posterior areas of the dentition has been thoroughly investigated, crown lengthening performed for esthetic reasons in the anterior areas is still a matter of debate and an evidence-based technique is not available. This paper provides accurate descriptions of the surgical and restorative phases of the esthetic crown-lengthening procedure by answering the following questions: what is the ideal surgical flap design? how much supporting bone should be removed? how should the position of the flap margin relate to the alveolar bone at surgical closure? and how should the healing phase be managed in relation to the timing and the position of the provisional restoration with respect to the gingival margin?

Alveolar ridge preservation in the esthetic zone.

In the esthetic zone, in the case of tooth extraction, the clinician is often confronted with a challenge regarding the optimal decision-making process for providing a solution using dental implants. This is because, after tooth extraction, alveolar bone loss and structural and compositional changes of the covering soft tissues, as well as morphological alterations, can be expected. Ideally, the therapeutic plan starts before tooth extraction and it offers three options: spontaneous healing of the extraction socket; immediate implant placement; and techniques for preserving the alveolar ridge at the site of tooth removal. The decision-making process mainly depends on: (i) the chosen time-point for implant placement and the ability to place a dental implant; (ii) the quality and quantity of soft tissue in the region of the extraction socket; (iii) the remaining height of the buccal bone plate; and (iv) the expected rates of implant survival and success. Based on scientific evidence, three time-periods for alveolar ridge preservation are described in the literature: (i) soft-tissue preservation with 6-8 weeks of healing after tooth extraction (for optimization of the soft tissues); (ii) hard- and soft-tissue preservation with 4-6 months of healing after tooth extraction (for optimization of the hard and soft tissues); and (iii) hard-tissue preservation with > 6 months of healing after tooth extraction (for optimization of the hard tissues).

Three-year analysis of zirconia implants used for single-tooth replacement and three-unit fixed dental prostheses: A prospective multicenter study.

AIM: The aim of the present investigation was to evaluate clinically and radiographically the outcome of zirconia oral implants after 3 years in function. MATERIALS AND METHODS: In 60 patients in need of either a single-tooth replacement or a three-unit fixed dental prosthesis (FDP), a total of 71 one-piece zirconia implants were placed and immediately restored with temporary fixed prostheses. After a period of at least 2 months in the mandible and at least 4 months in the maxilla, zirconia-based reconstructions were cemented. The implants were clinically and radiologically examined at implant insertion, prosthetic delivery, at 6 months and then yearly up to 3 years. A linear mixed model was used to analyze statistically the influence of prognostic factors on changes in the marginal bone level. RESULTS: Seventy-one implants (48 in the mandible, 23 in the maxilla) inserted in 60 patients were restored with 49 crowns and 11 FDP. One patient lost his implant after 5 weeks. Five patients with one implant each could not be evaluated after 3 years. Based on 55 patients with a total of 66 implants, the mean survival rate was 98.5% after 3 years in function. A statistically significant mean marginal bone loss (0.70 mm ± 0.72 mm) has been detected from implant insertion to the 3-year follow-up. The largest marginal bone loss occurred between implantation and prosthetic delivery (0.67 mm ± 0.56 mm). After delivery, no statistically significant bone level change was observed (0.02 mm ± 0.59 mm). None of the investigated prognostic factors had a significant influence on changes in the marginal bone level. CONCLUSIONS: After 3 years in function, the investigated one-piece zirconia implant showed a high survival rate and a low marginal bone loss. The implant system was successful for single-tooth replacement and three-unit FDPs. Further investigations with long-term data are needed to confirm these findings.