Three-Dimensional Finite Element Analysis and Biomechanical Analysis of Midfoot von Mises Stress Levels in Flatfoot, Clubfoot, and Lisfranc Joint Injury.

BACKGROUND Midfoot deformity and injury can affect the internal pressure distribution of the foot. This study aimed to use 3D finite element and biomechanical analyses of midfoot von Mises stress levels in flatfoot, clubfoot, and Lisfranc joint injury. MATERIAL AND METHODS Normal feet, flatfeet, clubfeet (30 individuals each), and Lisfranc injuries (50 individuals) were reconstructed by CT, and 3D finite element models were established by ABAQUS. Spring element was used to simulate the plantar fascia and ligaments and set hyperelastic coefficients in encapsulated bone and ligaments. The stance phase was simulated by applying 350 N on the top of the talus. The von Mises stress of the feet and ankle was visualized and analyzed. RESULTS The von Mises stress on healthy feet was higher in the lateral metatarsal and ankle bones than in the medial metatarsal bone. Among the flatfoot group, the stress on the metatarsals, talus, and navicular bones was significantly increased compared with that on healthy feet. Among patients with clubfeet, stress was mainly concentrated on the talus, and stress on the lateral metatarsal and navicular bones was significantly lower. The von Mises stress on the fractured bone was decreased, and the stress on the bone adjacent to the fractured bone was higher in Lisfranc injury. During bone dislocation alone or fracture accompanied by dislocation, the von Mises stress of the dislocated bone tended to be constant or increased. CONCLUSIONS Prediction of von Mises stress distribution may be used clinically to evaluate the effects of deformity and injury on changes in structure and internal pressure distribution on the midfoot.

Anatomically accurate model of EMG during index finger flexion and abduction derived from diffusion tensor imaging.

This study presents a modelling framework in which information on muscle fiber direction and orientation during contraction is derived from diffusion tensor imaging (DTI) and incorporated in a computational model of the surface electromyographic (EMG) signal. The proposed model makes use of the principle of reciprocity to simultaneously calculate the electric potentials produced at the recording electrode by charges distributed along an arbitrary number of muscle fibers within the muscle, allowing for a computationally efficient evaluation of extracellular motor unit action potentials. The approach is applied to the complex architecture of the first dorsal interosseous (FDI) muscle of the hand to simulate EMG during index finger flexion and abduction. Using diffusion tensor imaging methods, the results show how muscle fiber orientation and curvature in this intrinsic hand muscle change during flexion and abduction. Incorporation of anatomically accurate muscle architecture and other hand tissue morphologies enables the model to capture variations in extracellular action potential waveform shape across the motor unit population and to predict experimentally observed differences in EMG signal features when switching from index finger abduction to flexion. The simulation results illustrate how structural and electrical properties of the tissues comprising the volume conductor, in combination with fiber direction and curvature, shape the detected action potentials. Using the model, the relative contribution of motor units of different sizes located throughout the muscle under both conditions is examined, yielding a prediction of the detection profile of the surface EMG electrode array over the muscle cross-section.

Effect of Statistically Iterative Image Reconstruction on Vertebral Bone Strength Prediction Using Bone Mineral Density and Finite Element Modeling: A Preliminary Study.

Statistical iterative reconstruction (SIR) using multidetector computed tomography (MDCT) is a promising alternative to standard filtered back projection (FBP), because of lower noise generation while maintaining image quality. Hence, we investigated the feasibility of SIR in predicting MDCT-based bone mineral density (BMD) and vertebral bone strength from finite element (FE) analysis. The BMD and FE-predicted bone strength derived from MDCT images reconstructed using standard FBP (FFBP) and SIR with (FSIR) and without regularization (FSIRB0) were validated against experimental failure loads (Fexp). Statistical iterative reconstruction produced the best quality images with regard to noise, signal-to-noise ratio, and contrast-to-noise ratio. Fexp significantly correlated with FFBP, FSIR, and FSIRB0. FFBP had a significant correlation with FSIRB0 and FSIR. The BMD derived from FBP, SIRB0, and SIR were significantly correlated. Effects of regularization should be further investigated with FE and BMD analysis to allow for an optimal iterative reconstruction algorithm to be implemented in an in vivo scenario.

Integration of neural architecture within a finite element framework for improved neuromusculoskeletal modeling.

Neuromusculoskeletal (NMS) models can aid in studying the impacts of the nervous and musculoskeletal systems on one another. These computational models facilitate studies investigating mechanisms and treatment of musculoskeletal and neurodegenerative conditions. In this study, we present a predictive NMS model that uses an embedded neural architecture within a finite element (FE) framework to simulate muscle activation. A previously developed neuromuscular model of a motor neuron was embedded into a simple FE musculoskeletal model. Input stimulation profiles from literature were simulated in the FE NMS model to verify effective integration of the software platforms. Motor unit recruitment and rate coding capabilities of the model were evaluated. The integrated model reproduced previously published output muscle forces with an average error of 0.0435 N. The integrated model effectively demonstrated motor unit recruitment and rate coding in the physiological range based upon motor unit discharge rates and muscle force output. The combined capability of a predictive NMS model within a FE framework can aid in improving our understanding of how the nervous and musculoskeletal systems work together. While this study focused on a simple FE application, the framework presented here easily accommodates increased complexity in the neuromuscular model, the FE simulation, or both.

Finite element analysis relating shape, material properties, and dimensions of taenioglossan radular teeth with trophic specialisations in Paludomidae (Gastropoda).

The radula, a chitinous membrane with embedded tooth rows, is the molluscan autapomorphy for feeding. The morphologies, arrangements and mechanical properties of teeth can vary between taxa, which is usually interpreted as adaptation to food. In previous studies, we proposed about trophic and other functional specialisations in taenioglossan radulae from species of African paludomid gastropods. These were based on the analysis of shape, material properties, force-resistance, and the mechanical behaviour of teeth, when interacting with an obstacle. The latter was previously simulated for one species (Spekia zonata) by the finite-element-analysis (FEA) and, for more species, observed in experiments. In the here presented work we test the previous hypotheses by applying the FEA on 3D modelled radulae, with incorporated material properties, from three additional paludomid species. These species forage either on algae attached to rocks (Lavigeria grandis), covering sand (Cleopatra johnstoni), or attached to plant surface and covering sand (Bridouxia grandidieriana). Since the analysed radulae vary greatly in their general size (e.g. width) and size of teeth between species, we additionally aimed at relating the simulated stress and strain distributions with the tooth sizes by altering the force/volume. For this purpose, we also included S. zonata again in the present study. Our FEA results show that smaller radulae are more affected by stress and strain than larger ones, when each tooth is loaded with the same force. However, the results are not fully in congruence with results from the previous breaking stress experiments, indicating that besides the parameter size, more mechanisms leading to reduced stress/strain must be present in radulae.

Axially rigid steerable needle with compliant active tip control.

Steerable instruments allow for precise access to deeply-seated targets while sparing sensitive tissues and avoiding anatomical structures. In this study we present a novel omnidirectional steerable instrument for prostate high-dose-rate (HDR) brachytherapy (BT). The instrument utilizes a needle with internal compliant mechanism, which enables distal tip steering through proximal instrument bending while retaining high axial and flexural rigidity. Finite element analysis evaluated the design and the prototype was validated in experiments involving tissue simulants and ex-vivo bovine tissue. Ultrasound (US) images were used to provide visualization and shape-reconstruction of the instrument during the insertions. In the experiments lateral tip steering up to 20 mm was found. Manually controlled active needle tip steering in inhomogeneous tissue simulants and ex-vivo tissue resulted in mean targeting errors of 1.4 mm and 2 mm in 3D position, respectively. The experiments show that steering response of the instrument is history-independent. The results indicate that the endpoint accuracy of the steerable instrument is similar to that of the conventional rigid HDR BT needle while adding the ability to steer along curved paths. Due to the design of the steerable needle sufficient axial and flexural rigidity is preserved to enable puncturing and path control within various heterogeneous tissues. The developed instrument has the potential to overcome problems currently unavoidable with conventional instruments, such as pubic arch interference in HDR BT, without major changes to the clinical workflow.

A GPU-based caching strategy for multi-material linear elastic FEM on regular grids.

In this study, we present a novel strategy to the method of finite elements (FEM) of linear elastic problems of very high resolution on graphic processing units (GPU). The approach exploits regularities in the system matrix that occur in regular hexahedral grids to achieve cache-friendly matrix-free FEM. The node-by-node method lies in the class of block-iterative Gauss-Seidel multigrid solvers. Our method significantly improves convergence times in cases where an ordered distribution of distinct materials is present in the dataset. The method was evaluated on three real world datasets: An aluminum-silicon (AlSi) alloy and a dual phase steel material sample, both captured by scanning electron tomography, and a clinical computed tomography (CT) scan of a tibia. The caching scheme leads to a speed-up factor of ×2-×4 compared to the same code without the caching scheme. Additionally, it facilitates the computation of high-resolution problems that cannot be computed otherwise due to memory consumption.

An investigation into structural behaviors of skulls chewing food in different occlusal relationships using FEM.

OBJECTIVES: This study aims to investigate the effect of different occlusal relationships on skull structural and mechanical behaviors through simulation of chewing food. METHODS: Finite element (FE) skull models of occlusion for Class I, end-on Class II, and full-cusp Class II were generated. End-on Class II and full-cusp Class II were chosen as mild and severe Class II occlusions, respectively. A simplified food bolus was introduced between the upper and lower dentition of the right molars. Chewing food was simulated in the skulls by moving the mandible. An experiment was conducted to measure strains at selective locations and compared them to the analytical results for validation. RESULTS: In the early stages of mandibular movement, masticatory forces predicted from the skull models without food were lower than the skull models with food but increased drastically after occluding teeth full enough. As a result, the relationship between masticatory force and mandible movement shows that there is no significant difference between the skull models with food and without food in the range of human masticatory force, approximately 250 N. In all the cases of skulls including a food bolus, stress was similarly propagated from the mandible to the maxilla and concentrated in the same regions, including the mandibular notch and alveolar bone around the lower molars. CONCLUSION: It is predicted that there is no significant difference of bite force-mandible movement relationships and stress distributions of skull and teeth, between end-on Class II and full-cusp Class II models. When simulating chewing activities on candy and carrot, it is also found that there is no difference of masticatory performance between Class II occlusions, from structural as well as mechanical perspectives.

Finite element modeling to compare craniocervical motion in two age-matched pediatric patients without or with Down syndrome: implications for the role of bony geometry in craniocervical junction instability.

OBJECTIVE: Instability of the craniocervical junction (CCJ) is a well-known finding in patients with Down syndrome (DS); however, the relative contributions of bony morphology versus ligamentous laxity responsible for abnormal CCJ motion are unknown. Using finite element modeling, the authors of this study attempted to quantify those relative differences. METHODS: Two CCJ finite element models were created for age-matched pediatric patients, a patient with DS and a control without DS. Soft tissues and ligamentous structures were added based on bony landmarks from the CT scans. Ligament stiffness values were assigned using published adult ligament stiffness properties. Range of motion (ROM) testing determined that model behavior most closely matched pediatric cadaveric data when ligament stiffness values were scaled down to 25% of those found in adults. These values, along with those assigned to the other soft-tissue materials, were identical for each model to ensure that the only variable between the two was the bone morphology. The finite element models were then subjected to three types of simulations to assess ROM, anterior-posterior (AP) translation displacement, and axial tension. RESULTS: The DS model exhibited more laxity than the normal model at all levels for all of the cardinal ROMs and AP translation. For the CCJ, the flexion-extension, lateral bending, axial rotation, and AP translation values predicted by the DS model were 40.7%, 52.1%, 26.1%, and 39.8% higher, respectively, than those for the normal model. When simulating axial tension, the soft-tissue structural stiffness values predicted by the DS and normal models were nearly identical. CONCLUSIONS: The increased laxity exhibited by the DS model in the cardinal ROMs and AP translation, along with the nearly identical soft-tissue structural stiffness values exhibited in axial tension, calls into question the previously held notion that ligamentous laxity is the sole explanation for craniocervical instability in DS.

FEM simulation of a sono-reactor accounting for vibrations of the boundaries.

The chemical effects of acoustic cavitation are obtained in sono-reactors built-up from a vessel and an ultrasonic source. In this paper, simulations of an existing sono-reactor are carried out, using a linear acoustics model, accounting for the vibrations of the solid walls. The available frequency range of the generator (19-21 kHz) is systematically scanned. Global quantities are plotted as a function of frequency in order to obtain response curves, exhibiting several resonance peaks. In absence of the precise knowledge of the bubbles size distribution and spatial location, the attenuation coefficient of the wave is taken as a variable, but spatially uniform parameter, and its influence is studied. The concepts of acoustic energy, intensity, active power, and source impedance are recalled, along with the general balance equation for acoustic energy, which is used as a convergence check of the simulations. It is shown that the interface between the liquid and the solid walls cannot be correctly represented by the simple approximations of either infinitely soft, or infinitely hard boundaries. Moreover, the liquid-solid coupling allows the cooling jacket to receive a noticeable part of the input power, although it is not in direct contact with the sonotrode. It may therefore undergo cavitation and this feature opens the perspective to design sono-reactors which avoid direct contact between the working liquid and the sonotrode. Besides, the possibility to shift the main pressure antinode far from the sonotrode area by exciting a resonance of the system is examined.

Three-dimensional finite element modeling from CT images of tooth and its validation.

The aim of this study was to develop a three-dimensional (3D) finite element (FE) model of a sound extracted human second premolar from micro-CT data using commercially available software tools. A detailed 3D FE model of the tooth could be constructed and was experimentally validated by comparing strains calculated in the FE model with strain gauge measurement of the tooth under loading. The regression coefficient and its standard error in the regression analysis between strains calculated by the FE model and measured with strain gauge measurement were 0.82 and 0.06, respectively, and the correlation coefficient was found to be highly significant. These results suggested that an FE model reconstructed from micro-CT data could be used as a valid model to estimate the actual strains with acceptable accuracy.

A Finite Element Solution of the Forward Problem in EEG for Multipolar Sources.

Multipolar source models have been presented in the context of electro/magnetoencephalography (E/MEG) to compensate for the limitations of the classical equivalent current dipole to represent realistic generators of brain activity. Although there exist several reports accounting for the advantages of multipolar components over single dipoles, there is still no available numerical implementation in fully personalized scenarios. In this paper, we present, for the first time, a finite element framework for simulating EEG signals generated by multipolar current sources in individualized, heterogeneous, and anisotropic head models. This formulation is based on the subtraction approach, guaranteeing the existence and uniqueness of the solution. In particular, we analyze the cases of monopolar, dipolar, and quadrupolar source components, for which we study their performance in idealized and realistic head models. Numerical solutions are compared with analytical formulas in multi-layered spherical models. Such formulas are available in the case of monopolar and dipolar sources, and here derived for the quadrupolar components. We finally illustrate their advantages in the description of extended current generators using a realistic head model. The framework presented here enables further analysis towards the estimation of biophysically principled source parameters from standard E/MEG experiments.

Numerical simulation of transapical off-pump mitral valve repair with neochordae implantation.

BACKGROUND: Transapical off-pump mitral valve (MV) repair is a novel minimally-invasive surgical technique, allowing to correct mitral regurgitation (MR) caused by chordae tendineae rupture. While numerical simulation of the MV structure has proven to be useful to evaluate the effects of the MV surgical repair techniques, no numerical simulation studies on the outcomes of transapical MV repair have been done up to now. OBJECTIVE: The purpose of this study is to evaluate the transapical MV repair using finite element modeling and to determine the effect of the neochordal length on the function of the prolapsing MV. METHODS: The reconstruction of the MV geometry based on the patient-specific data was performed. In order to simulate prolapse, chordae inserted into the middle segment of the posterior leaflet (P2) were ruptured. A total of four virtual transapical repairs using neochordae of different length were performed. The function of the MV before and after virtual repairs was simulated. RESULTS: The evaluation of the effect of the neochordal length on post-repair MV function showed that the length of the implanted neochordae has a significant impact on the correction of MR caused by chordae tendineae rupture. CONCLUSIONS: The presented results can improve the understanding of the effects of transapical MV repair.

Predicting revision risk for aseptic loosening of femoral components in total hip arthroplasty in individual patients--a finite element study.

Advances in surgical procedure, prosthesis design, and biomaterials performance have considerably increased the longevity of total joint replacements. Preoperative planning is another step in joint replacement that may have the potential to improve clinical outcome for the individual patient, but has remained relatively consistent for a long time. One means of advancing this aspect of joint replacement surgery may be to include predictive computer simulation into the planning process. In this article, the potential of patient-specific finite element analysis in preoperative assessment is investigated. Seventeen patient-specific finite element models of cemented Charnley reconstructions were created, of which six were early (<10 years) revisions. Creep was simulated using a Maxwell model, and fatigue damage was simulated using an anisotropic continuum damage formulation. Account was taken of the relationship between annual loading cycles and age, and stair-climbing loads were included using a walking to stair-climbing cycle ratio of 9:1. Simulations for the equivalent of 10 years of loading were performed. Accumulated damage, inducible displacement, and migration were computed. Five of the six early revisions had the highest migration indicating that migration could have been used to identify early failures of these prostheses. Resultant migration showed the most significant difference between the early revised and unrevised groups (p = 0.0024). Furthermore, this trend was apparent from 1 year postimplantation (p = 0.0052). This ability to differentiate early revisions shows that computational simulation of aseptic loosening in cemented prostheses could prove clinically useful in helping surgeons optimize the preoperative plan for individual patients.

Effects of malalignment angle on the contact stress of knee prosthesis components, using finite element method.

In this paper, the complex 3D virtual model of the prosthetic knee is obtained using embedded applications: DesignModeler and SpaceClaim under ANSYS Workbench 14.5 software package. A number of six cases of prosthetic knee joint assembly, depending on the malalignment angle, are developed. Stress maps and the values of the maximum von Mises stress on the three prosthesis components: polyethylene insert, tibial component and femoral component, for all studied prosthetic knee assemblies were obtained. The results show that as the malalignment angle increases, the values of von Mises stresses increase in all prosthesis components. The parameterized virtual models of the knee prosthesis components allow different changes in shape or dimensions, which can lead to the optimization of the implant and to the improvement of the prosthetic knee biomechanics.

Numerical analysis of tooth movement in different plans of transparent tooth correction therapies.

BACKGROUND: The objective of this study was to investigate how treatment strategies in the same treatment affected the canine's initial displacement and the stress in periodontal ligament using three-dimensional finite element analysis. And to find out the way to design an effective treatment plan. METHODS: Based on computed tomography images of the teeth and their supporting tissues, solid models were used to build finite element models. Three treatment plans of three different transparent tooth correction therapies finite element-analyses were operated. RESULTS: The canine's initial displacement and stresses' distribution in periodontal ligament were obtained. CONCLUSIONS: For rotation movement, the canine should rotate along tooth long axis, and not combine with other kinds of tooth movement as possible. For translation movement, the combination of translation and inclination movement is helpful for the treatment.

Finite element modelling of a residual lower-limb in a prosthetic socket: a survey of the development in the first decade.

A review is presented of the existing finite element models developed from 1987 to 1996 for the biomechanics of lower-limb prostheses. Finite element analysis can be a useful tool in investigating the mechanical interaction between the residual limb and its prosthetic socket, and in computer-aided design and computer-aided manufacturing of prosthetic sockets. Various assumptions and simplifications are made in these models to simplify the actual problem with complex geometry, material properties, boundary and interfacial conditions, as well as loading situations. The analyses can provide the information on the stress distribution at the stump/socket interface and within the residual limb tissues. More recently, nonlinear models have been developed taking into consideration the process of socket rectifications, the slip/friction conditions and material large deformation. The models so far developed have provided some basic understanding of the biomechanics. Comparison of the predictions of these models with experimental measurements indicated that the predicted stresses were within the ranges measured, although one-to-one correspondence was difficult to achieve. Further research is still required in order to improve these models to obtain higher precision in the results taking into account nonlinear and dynamic effects.

Mechanism of human accommodation as analyzed by nonlinear finite element analysis.

Results of nonlinear finite element analysis support the Schachar theory of accommodation and demonstrate that the long-held Helmholtz theory of accommodation is impossible.

Assessment of trabecular bone yield and post-yield behavior from high-resolution MRI-based nonlinear finite element analysis at the distal radius of premenopausal and postmenopausal women susceptible to osteoporosis.

RATIONALE AND OBJECTIVES: To assess the performance of a nonlinear microfinite element model on predicting trabecular bone yield and post-yield behavior based on high-resolution in vivo magnetic resonance images via the serial reproducibility. MATERIALS AND METHODS: The nonlinear model captures material nonlinearity by iteratively adjusting tissue-level modulus based on tissue-level effective strain. It enables simulations of trabecular bone yield and post-yield behavior from micro magnetic resonance images at in vivo resolution by solving a series of nonlinear systems via an iterative algorithm on a desktop computer. Measures of mechanical competence (yield strain/strength, ultimate strain/strength, modulus of resilience, and toughness) were estimated at the distal radius of premenopausal and postmenopausal women (N = 20, age range 50-75) in whom osteoporotic fractures typically occur. Each subject underwent three scans (20.2 ± 14.5 days). Serial reproducibility was evaluated via coefficient of variation (CV) and intraclass correlation coefficient (ICC). RESULTS: Nonlinear simulations were completed in an average of 14 minutes per three-dimensional image data set involving analysis of 61 strain levels. The predicted yield strain/strength, ultimate strain/strength, modulus of resilience, and toughness had a mean value of 0.78%, 3.09 MPa, 1.35%, 3.48 MPa, 14.30 kPa, and 32.66 kPa, respectively, covering a substantial range by a factor of up to 4. Intraclass correlation coefficient ranged from 0.986 to 0.994 (average 0.991); CV ranged from 1.01% to 5.62% (average 3.6%), with yield strain and toughness having the lowest and highest CV values, respectively. CONCLUSIONS: The data suggest that the yield and post-yield parameters have adequate reproducibility to evaluate treatment effects in interventional studies within short follow-up periods.

Comportamento biomecânico de caninos desgastados por atrição frente a diferentes técnicas restauradoras / Canine guide reconstruction with diferente technics: influence on biomechanics properties

O objetivo do estudo foi avaliar o comportamento mecânico de materiais restauradores utilizados na reabilitação da guia canino. O estudo foi dividido em uma etapa in sílico e outra in vitro. Dez modelos 3D de dentes caninos hígidos foram obtidos por engenharia reversa e utilizados como Grupo Controle (n = 10) para o teste in sílico por meio da análise por elementos finitos (FEA). Um desgaste incisal de 2 mm foi simulado em cada amostra 3D e reabilitado com restauração incisal direta de resina composta (Grupo IRC, n = 10) e indireta de cerâmica (Grupo IC, n = 10). Os mesmos modelos também receberam, além do desgaste incisal, um preparo vestibular para faceta laminada, restaurados com os mesmos materiais, compondo os Grupos FRC (faceta de resina composta, n = 10) e FC (faceta cerâmica, n = 10). Os modelos foram exportados para um software de engenharia assistida por computador (CAE) e as geometrias foram transformadas em malhas de elementos tetraédricos, consideradas sólidas, isotrópicas, homogêneas e lineares. Uma carga de 100 N foi aplicada simulando a desoclusão pelo canino para análise mecânica estrutural dinâmica. A deformação total foi mensurada e a tensão máxima principal foi usada como critério de falha. Com base nos resultados da avaliação in sílico, dois tipos de restauração foram selecionados para a fase in vitro, onde realizou-se um ensaio mecânico de fadiga para análise do desgaste. Trinta dentes caninos hígidos foram distribuídos em três grupos: Controle (n = 10), IRC (n = 10) e FC (n = 10). As amostras foram submetidas ao ensaio de fadiga em cicladora mecânica com deslizamento de 2 mm por 240.000 ciclos, carga de 49 N e 4 Hz de frequência, imersas em água em temperatura ambiente. A cada 60.000 ciclos as amostras foram moldadas e seus modelos escaneados para avaliação da quantidade de desgaste através da técnica de correlação por imagem digital, quantificando a perda de estrutura a cada intervalo. As técnicas restauradoras com resina composta sofreram maior deformação total, tendo a cerâmica um comportamento semelhante ao dente hígido. A probabilidade de falha no movimento de desoclusão foi menor na cerâmica. Para o desgaste, não houve diferença significante entre grupos experimentais até 180.000 ciclos. Aos 240.000 ciclos, a resina composta apresentou maior desgaste que a cerâmica (p = 0,02). Todos os grupos provocaram desgaste em seus antagonistas, mas não houve diferença significante entre eles (p < 0,05). Dentro das limitações deste estudo, pode-se concluir que os laminados cerâmicos apresentaram menor desgaste, deformação e probabilidade de falha na restauração da guia canino. Ainda, a anatomia do dente e o tipo de restauração influenciaram o comportamento dos materiais(AU)

The purpose of this study was to evaluate the mechanical behavior of materials restorative used in rehabilitation of canine guide. The study was divided in two parts in silico and in vitro test. Ten 3D models of sound canine teeth were obtained by reverse engineering technique and used as Control Group (n = 10) to in silico test by finite elements analysis (FEA). A 2 mm wear were simulated in each 3D sample and restored according to restorative material; Group IRC (Incisal Composite Resin, n=10) and Group IC (Incisal Ceramic, n = 10). Laminate preparations were modeled and restored with the same materials, Group FRC (Laminate Composite Resin, n=10) and Group FC (Laminate Ceramic, n = 10). All models were exported to Computer Aided Engineering (CAE) software, the geometries were meshed with tetrahydric elements and all contacts were considered perfectly bonded. The load simulated the canine guide (100 N) and the assembly was constrained at the bottom surface to run a structural mechanic dynamic analysis. The Total Deformation was measured and Maximum Principal Stress was used as failure criteria. Thirty sound canine tooth were divided in three groups to in vitro test; Control (n = 10), IRC (n = 10) and FC (n = 10). The samples were subjected to the fatigue test in a wear machine for 240.000 cycles, load of 49 N, frequency of 4 Hz, sliding distance of 2 mm in water at room temperature. The samples were molded every 60.000 cycles and their models scanned to evaluate wear by digital image correlation. Composite resin groups showed higher total deformation and ceramic groups had a more similar behavior to the control group. The probability of failure was lower for the ceramic in the canine guidance. For wear, there was no significant difference between groups up to 180.000 cycles. After 240.000 cycles, the wear was greater in the IRC group (p = 0,02). The wear of the antagonists was not statistically different between groups. Within the limitations of this study, it can be concluded that the ceramic laminates showed less wear, deformation and probability of failure in restoring of the canine guide. In addition, anatomy of the tooth and type of restoration influenced the behavior of the materials(AU)