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1.
J Craniofac Surg ; 31(6): 1734-1738, 2020 Sep.
Article in English | MEDLINE | ID: mdl-32371693

ABSTRACT

PURPOSE: The purpose of this study is to examine the association between type of facial osteotomies performed during orthognathic surgery and postoperative outcomes including complications, length of stay, and readmission. METHODS: A retrospective review of orthognathic surgery cases from the Pediatric Health Information System (PHIS) database from 2004 to 2014 was undertaken. Osteotomy procedures were classified as Le Fort 1 (LF 1), Mandibular osteotomy, Genioplasty or their combinations. Primary outcome variable was major complications. Secondary outcomes included postoperative LOS > 1 day and 90-day readmission. Random-intercept logistic regression models were utilized to assess the association between the type of osteotomy performed and the outcomes. Bonferroni approach was used to account for multiple comparisons. RESULTS: The sample included 5413 patients, with a mean age of 17.1 ±â€Š1.68 years and 60.65% were female. The most common procedures were LF1 (39.4%), followed by bimaxillary surgery (23%). Major complications occurred in 8.57% of patients, postoperative LOS > 1 day in 52.4% and 90-day all-cause readmission in 11.16%. In adjusted analyses comparing LF1 compared to mandibular osteotomies, there were no significant differences for major complications (OR = 0.78), 90-day readmission rate (OR = 0.98). However, LF1 was associated with an increased odds for LOS compared to mandibular osteotomies (OR = 1.42). Addition of osteotomies is associated with a significant increase in LOS (P < 0.001). CONCLUSIONS: Patients undergoing orthognathic surgery demonstrated increased length of stay for LF1 or bimaxillary osteotomies. Osteotomy type did not impact the odds of readmission or complications. The trends revealed should be helpful for patient counseling.


Subject(s)
Jaw Diseases/surgery , Mandibular Osteotomy , Adolescent , Female , Genioplasty , Humans , Length of Stay , Male , Morbidity , Osteotomy, Le Fort , Retrospective Studies
2.
J Craniofac Surg ; 31(4): e347-e352, 2020 Jun.
Article in English | MEDLINE | ID: mdl-32149968

ABSTRACT

The aim of the present work is to evaluate the most suitable surgical technique in relation to location and extent of medication-related osteonecrosis of the jaws (MRONJ) through comparison of success rate between the routinely used mucoperiostal flaps and different local flaps designs and propose a standardization of surgical procedures according to MRONJ stage and localization with 2 objectives: to provide the surgeon with an algorithm of treatment according to MRONJ localization and extension; to maximize the success of surgical treatment.Thirteen consecutive patients affected by focal MRONJ were surgically treated with radical osteotomy at the Center for Treatment of the Osteonecrosis of the Jaws (University of Messina, Italy).Initial defects were classified according to the classification of the Italian Societies of Oral Medicine and Maxillofacial Surgery (the SICMF-SIPMO staging system) which consider not only bone exposure but also radiological bone involvement. Treatment outcome was retrospectively assessed according to the different adopted surgical procedure: mucoperiostal flaps (GROUP A) advanced mucoperiostal flaps or rotation flaps (GROUP B) local flaps (GROUP C).Outcome after surgical treatment of focal MRONJ was positive in every group irrespective of MRONJ localization and extension. This may be due to the appropriate selection of surgical procedure.The results obtained demonstrated that focal MRONJ surgical treatment is a reliable procedure irrespective of the initial clinical situation. Radical osteotomy combined with appropriate selection of soft tissue management is crucial.


Subject(s)
Jaw Diseases/surgery , Orthognathic Surgical Procedures , Surgical Flaps/surgery , Humans , Italy , Jaw , Osteotomy , Retrospective Studies , Treatment Outcome
3.
J Craniofac Surg ; 31(4): 931-933, 2020 Jun.
Article in English | MEDLINE | ID: mdl-31985596

ABSTRACT

INTRODUCTION: Digital simulators are potential solutions to challenges facing surgical education. The authors sought to evaluate the reach and utilization of a freely-accessible craniofacial surgery digital educational simulator. More importantly, we compare usage patterns between web-based and mobile-based platforms. METHODS: A 3-way collaboration between academic, non-profit (myFace, New York, NY), and biotechnology (Biodigital, New York, NY) stakeholders in 2015 produced the Craniofacial Interactive Virtual Assistant Pro (CIVA-Pro). CIVA-Pro is a freely-accessible craniofacial surgery digital educational simulator. In addition to the web-based platform, a mobile-based platform was launched in 2017. Usage analytics were collected and analyzed. RESULTS: Since its launch, 751 registered users from 117 countries had accessed CIVA-Pro. The total number of sessions was 9531, including 7500 web and 2031 mobile sessions. The total screen time was 403.9 hours, 290.3 for the web and 113.6 for the mobile platform. Comparison of the mean monthly screen time and number of monthly sessions between platforms since 2017 demonstrated a significantly higher mean monthly screen time (60.1 ±â€Š33.2 versus 29.4 ±â€Š16.5 hours; P = 0.002) and number of sessions (110.2 ±â€Š36.1 versus 58.1 ±â€Š31.9; P < 0.0001) for the mobile-based platform. The mean screen time per session was comparable (P = 0.86). CONCLUSION: A freely available digital craniofacial surgery educational simulator designed for surgical trainees can achieve significant global reach. Significantly higher utilization of the mobile-based platform of the simulator as compared to the web-based platform reinforces the need to invest in user-friendly, easily accessible, and widely available digital educational resources by key stakeholders to ensure optimal plastic surgery trainee education.


Subject(s)
Face/surgery , Jaw Diseases/surgery , Humans , New York , Plastic Surgery Procedures , Surgery, Plastic
4.
J Craniofac Surg ; 31(6): e620-e622, 2020 Sep.
Article in English | MEDLINE | ID: mdl-32398624

ABSTRACT

In late 2019, a novel coronavirus strain, SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2), also known as coronavirus disease 2019 (COVID-19), triggered a global pandemic as the virus spread from the Wuhan Province, China, across all continents. Although infrequent, severe respiratory infection and death caused by SARS-CoV-2 is disproportionately high amongst healthcare providers such as craniofacial surgeons who work in the head and neck region. Factors this impact SARS-CoV-2 transmission include: (1) high viral loads in the mucosa of the oral and nasopharynx, (2) limited and/or imprecise disease screening/confirmation testing, (3) access to and appropriate use of personal protective equipment (PPE).


Subject(s)
Betacoronavirus , Coronavirus Infections/prevention & control , Face/surgery , Jaw Diseases/surgery , Pandemics/prevention & control , Pneumonia, Viral/prevention & control , Betacoronavirus/physiology , COVID-19 , Coronavirus Infections/transmission , Humans , Laryngeal Mucosa/virology , Mouth Mucosa/virology , Nasal Mucosa/virology , Personal Protective Equipment , Pneumonia, Viral/transmission , SARS-CoV-2 , Viral Load
5.
J Craniofac Surg ; 31(2): e156-e161, 2020.
Article in English | MEDLINE | ID: mdl-31977697

ABSTRACT

The term osteomyelitis of the jaws identifies different pathological patterns characterized by the involvement of the cortical bone and bone marrow in osteoarticular infections.At the head and neck level, the segment most affected by osteomyelitis is the mandible and in most of the cases the cause of the infection is bacterial, as a result of pulp or periodontal infections, post-extraction alveolitis, foreign bodies and fractures. The mandibular PCO often presents with an insidious onset, without a striking acute phase, and it is characterized by recurrent episodes of pain, swelling, lockjaw, latero-cervical lymphadenopathy, without signs of suppuration.Three patients have been collected and recorded for the study.The authors believe that in the more advanced cases of PCO in adult patients, in which the mandibular bone appears almost entirely sclerotic and deformed, and that are not responsive to pharmacological therapy or to conservative surgical therapies such as decortication, it is necessary to perform a complete removal of the portion affected by osteomyelitis, with lower alveolar nerve preservation and contextual reconstruction with free microvascular bone flap.Our review aims to describe the clinico-pathological features of a rare pathological entity, propose a surgical treatment algorithm using computer-aided-design/computer-aided manufacturing technology and review the existing literature.


Subject(s)
Jaw Diseases/surgery , Mandible/surgery , Osteomyelitis/surgery , Adult , Chronic Disease , Computer-Aided Design , Female , Free Tissue Flaps/surgery , Humans , Jaw Diseases/diagnostic imaging , Male , Mandible/diagnostic imaging , Mandibular Reconstruction , Osteomyelitis/diagnostic imaging , Young Adult
6.
J Craniofac Surg ; 30(4): 980-984, 2019 Jun.
Article in English | MEDLINE | ID: mdl-30807477

ABSTRACT

The aim of this study is to evaluate donor- and recipient-site complications of iliac bone grafting for the reconstruction of atrophic jaws.Our study includes 86 consecutive patients with atrophic jaws who underwent iliac bone grafting surgery. At the donor site, hematoma, infection, paresthesia, chronic pain, prolonged gait disturbance, fracture of the ilium, and esthetic concerns; at the recipient site, hematoma, infection, prolonged pain, graft exposure, graft loss, and loss of the implants were evaluated.Grafting was successfully performed in all patients. The mean follow-up period was 35 months. Prolonged gait disturbance (20.9%) and paresthesia (9.3%) were the most frequently observed donor-site complications. At the recipient site, hematoma (8.1%), infection (12.8%), prolonged pain (11.6%), partial graft exposure (33.7%), total graft exposure (7%), partial graft loss (17.4%), and total graft loss (5.8%) were observed.Reconstruction of atrophic jaws can be achieved successfully with iliac bone grafting. However, there are possible donor- and recipient-site complications that have to be taken into consideration.


Subject(s)
Bone Transplantation/adverse effects , Ilium/transplantation , Jaw Diseases/surgery , Orthognathic Surgical Procedures/adverse effects , Gait/physiology , Graft Survival , Hematoma/etiology , Humans , Paresthesia/etiology , Postoperative Complications/epidemiology
7.
J Craniofac Surg ; 30(5): 1533-1538, 2019 Jul.
Article in English | MEDLINE | ID: mdl-31299761

ABSTRACT

PURPOSE: To investigate short- and long-term three-dimensional changes of pharyngeal airway morphology and hyoid bone position in dento-skeletal class III deformity patients after 2-jaw orthognathic surgery with segmentation. METHODS: A retrospective analysis has been performed on patients with dento-skeletal class III deformity who had undergone orthognathic 2-jaw surgery with segmentations, presenting both pre- and post-surgical cone-beam computed tomographys. Three-dimensional skeletal movements, pharyngeal airway changes and hyoid bone position were measured and correlated. RESULTS: The mean short term postsurgical review period for all included 47 patients was 5.8 ±â€Š2.2 months. Thirteen patients among them provided a mean long term period of 26.4 ±â€Š3.4 months. The mean postsurgical maxillary movement was 2.29 ±â€Š2.49 mm in vertical, 2.02 ±â€Š3.45 mm in horizontal direction, respectively, while the mandibular movement was 6.49 ±â€Š4.58 mm in vertical, and -5.85 ±â€Š6.13 mm in horizontal direction. In short-term, the vertical length of nasopharynx was found to be reduced (P = 0.005) but increased for the oropharynx (P < 0.001). Furthermore, the oropharyngeal minimum cross-sectional area has decreased significantly (P = 0.013). The hyoid bone moved posterosuperiorly, however, with only its horizontal movement found to be significant (P = 0.043). No significant result was detected in long-term analyses, neither in postsurgical pharyngeal airway changes nor the hyoid bone movement. There were no significant differences in pharyngeal airway measurements (P > 0.05) detected between patients with and without genioplasty advancement. CONCLUSION: Two-jaw orthognathic surgery in dento-skeletal class III patients led to a statistically non-significant reduction of the post-surgical airway volume in both short- and long-term. Although the post-surgical oropharyneal minimum cross-sectional area was decreased significantly in the short term, this finding did not persist in the long term.


Subject(s)
Jaw Diseases/surgery , Orthognathic Surgery , Pharynx/anatomy & histology , Cross-Sectional Studies , Genioplasty , Humans , Hyoid Bone/surgery , Mandible/surgery , Maxilla/surgery , Nasopharynx , Oropharynx , Orthognathic Surgical Procedures/methods , Retrospective Studies
8.
J Prosthodont ; 28(2): e811-e816, 2019 Feb.
Article in English | MEDLINE | ID: mdl-28872729

ABSTRACT

PURPOSE: After marsupialization of benign tumors and jawbone cysts, insertion of an obturator prosthesis maintains the surgical opening and improves hygiene. To date, there have been no reports clarifying the relationship between the obturator design and treatment outcomes. The purpose of this study was to examine the survival rate of three types of obturator, and to investigate the factors that expedite the removal of the obturator. MATERIALS AND METHODS: The subject group comprised 100 patients who had an obturator inserted after marsupialization at Kagoshima University Hospital between May 31, 2012 and March 31, 2015; 73 patients with lesions in the mandible were eligible. Three types of mandibular obturator were designed and inserted, considering the teeth missing, the anteroposterior position of the lesion, and the buccolingual direction of marsupialization. The endpoint of this study was defined as the removal of the obturator. The analyzed predictor values for the endpoint were age, gender, remaining teeth, nature of primary disease, anteroposterior location of primary disease, buccolingual direction of marsupialization, type of obturator, and dates of insertion and removal. RESULTS: No significant differences were found in the cumulative survival rate among the three types of obturator. Early obturator removal was more frequent in patients with cysts, anterior lesions, and/or marsupialization from the occlusal direction CONCLUSIONS: Because obturator design had minimal effect on the ability of the appliance to maintain the surgical opening, it is preferable to use the least invasive design. Our findings also suggest that the follow-up examination should account for the type of primary disease, the anteroposterior location of the lesion, and the buccolingual direction of marsupialization.


Subject(s)
Bone Plates , Jaw Diseases/surgery , Adult , Age Factors , Bone Plates/adverse effects , Female , Humans , Jaw/diagnostic imaging , Jaw/pathology , Jaw Cysts/surgery , Jaw Neoplasms/surgery , Male , Prosthesis Failure , Radiography, Panoramic , Retrospective Studies , Risk Factors , Sex Factors
9.
Khirurgiia (Mosk) ; (3): 65-72, 2019.
Article in Russian | MEDLINE | ID: mdl-30938359

ABSTRACT

AIM: To develop the technology of manufacturing of reconstructive allogenic bone graft with individual parameters by using of digital prototyping and modeling. MATERIAL AND METHODS: Allogeneic cadaveric bone blocks were used as material. The following methods were used to develop a manufacturing technology for personalized allogenic reconstructive bone implant: harvesting and special preparation of cadaveric material, primary disinfection, viral inactivation, ultrasound management, lyophilization of bone material, CT-examination of patients with various bone defects, digital prototyping and modeling, milling on a machine with numerical program control, X-ray sterilization. RESULTS: The technology of manufacturing of reconstructive allogenic bone graft with individual parameters was successfully tested in the treatment of 24 patients with post-traumatic, destructive-dystrophic and degenerative defects of jaws in 2012-2015. Final reconstructive allogenic bone implant has a personalized 3D-geometry in accordance with individual maxillofacial anatomy of particular patient. One of implant surfaces is fully congruent to the jaw bone defect, the others form the width, height and volume of reconstructive bone implant considering personified maxillofacial features. All above-mentioned features of bone implant are important to restore chewing function of dental system. CONCLUSION: The problem of bone implant personification may be resolved by using of computed tomography followed by digital analysis of jaw structure, technologies for digital reconstruction of bone defects (digital prototyping and modeling) and digital manufacturing.


Subject(s)
Allografts , Bone Substitutes , Bone Transplantation , Jaw Diseases/surgery , Printing, Three-Dimensional , Bone Substitutes/therapeutic use , Cadaver , Humans , Imaging, Three-Dimensional , Patient-Specific Modeling , Plastic Surgery Procedures , Russia , Tomography, X-Ray Computed , Transplantation, Homologous
10.
J Craniofac Surg ; 29(3): e248-e250, 2018 May.
Article in English | MEDLINE | ID: mdl-29303857

ABSTRACT

BACKGROUND: Reconstruction of an oromandibular defect presents a considerable surgical challenge. But since the advent of microvascularized free flap reconstructive surgery, outcomes have improved significantly so that today almost any defect may be reconstructed. Recently, virtual surgical planning has reduced surgical time, the morbidity associated with surgery, and surgical precision. OBJECTIVE: This article reports a complex patient with a composite oromandibular defect. METHODS: The patient had undergone multiple surgeries with bad results. She presented an orostoma of 5 cm in diameter, osteoradionecrosis and fracture of the left mandibular body, and relapse in the ipsilateral posterior maxilla. Reconstruction was performed by means of a scapular/parascapular chimeric free flap. A customized reconstruction plate was designed virtually based on the mirror image of the contralateral mandibular body. Surgery and the postoperative phase passed without incident. The patient recovered vocal, swallowing, and respiratory function without any problems. At the end of a 1-year follow-up, no complications or tumor relapse had occurred. CONCLUSIONS: Composite defects are a surgical challenge in which free flap reconstruction is an evolution that has facilitated treatment and led to improved outcomes. Virtual treatment planning produces more exact results and greater control of surgical techniques.


Subject(s)
Free Tissue Flaps/surgery , Jaw Diseases/surgery , Mandible/surgery , Plastic Surgery Procedures/methods , Scapula/surgery , Surgery, Computer-Assisted , Aged , Female , Humans , Osteoradionecrosis/surgery
11.
Stomatologiia (Mosk) ; 97(2): 37-40, 2018.
Article in Russian | MEDLINE | ID: mdl-29795104

ABSTRACT

The study objectives were to determine the significance of deep neck odontogenic infections severity to predict the postoperative morbidity. Observational study was conducted in 2014-2015. A continuous sample of 38 patients who were urgently hospitalized in the Novosibirsk Regional Clinical Hospital with deep neck odontogenic infections and operated on the day of hospitalization was analyzed. SAPS scale rates correlated positively with the duration of the artificial lungs ventilation (ALV). The positive balance of the introduced and withdrawn liquid in the first day of the postoperative period is associated with the ALV duration, which requires accurate dosing of the infusion volumes. The described protocol of perioperative care significantly decreases morbidity in patients with deep neck odontogenic infections.


Subject(s)
Anesthesia, General , Hospitalization , Neck , Soft Tissue Infections , Critical Care , Humans , Jaw Diseases/surgery , Neck/pathology , Retrospective Studies , Soft Tissue Infections/surgery
12.
J Oral Maxillofac Surg ; 75(8): 1668-1678, 2017 Aug.
Article in English | MEDLINE | ID: mdl-28282517

ABSTRACT

PURPOSE: Cysts are common pathologic entities in the oral and maxillofacial region. Enucleation is commonly used for treatment and is occasionally followed by bone grafting. However, no studies have evaluated factors affecting the failure of grafts used for cystic defects in the oral and maxillofacial region. Therefore, the present study was conducted to determine the risk factors for postoperative graft failure in patients treated with cyst enucleation and simultaneous bone grafting. MATERIALS AND METHODS: Clinical data for 305 patients who had undergone cyst enucleation with simultaneous bone grafting were retrospectively investigated in this multicenter case-and-control study. The predictor variables included host, pathologic, and treatment factors. The outcome variable was success or failure of the bone graft. Descriptive statistics were computed, and the P value was set at .05. RESULTS: Bone graft failure was observed in 48 cases. The mean duration from surgery to failure was 38.7 days. Multivariable logistic regression analysis showed a significant association between graft failure and younger age (odds ratio [OR] = 1.033; P = .016), smoking (OR = 2.598; P = .017), preoperative infection (OR = 4.660; P = .001), large cysts (OR = 1.052; P = .010), impaction of the mandibular third molar in the cystic cavity (OR = 3.021; P = .007), perilesional osteosclerosis (OR = 4.973; P = .001), and the use of mixed non-autogenous and autogenous bone grafts (OR = 3.891; P = .007). CONCLUSIONS: This study provides a list of important factors that should be considered by clinicians planning enucleation and simultaneous bone grafting for cysts in the oral and maxillofacial region.


Subject(s)
Bone Transplantation , Graft Rejection/etiology , Jaw Diseases/surgery , Odontogenic Cysts/surgery , Postoperative Complications/etiology , Adult , Age Factors , Bacterial Infections/etiology , Case-Control Studies , Female , Follow-Up Studies , Humans , Male , Middle Aged , Republic of Korea , Retrospective Studies , Risk Factors , Statistics as Topic
13.
J Oral Maxillofac Surg ; 75(1): 119-128, 2017 Jan.
Article in English | MEDLINE | ID: mdl-27450749

ABSTRACT

PURPOSE: The aim of this study was to describe the effect of vancomycin-impregnated calcium sulfate in the treatment of osteomyelitis of the jaw. MATERIALS AND METHODS: Twelve patients who were diagnosed with osteomyelitis of the jaw underwent treatment with vancomycin-impregnated calcium sulfate since July 2014 at the Department of Oral and Maxillofacial Surgery, School of Stomatology, China Medical University (Shenyang, China). All patients underwent debridement of nonviable bone and implantation of vancomycin-impregnated calcium sulfate. The wounds were covered with an acellular dermal matrix and sutured. RESULTS: Ten patients had satisfactory wound healing. However, 2 cases of maxillary central osteomyelitis had delayed wound healing. The wounds healed after the surgical site was resutured under local anesthesia. At 3 months, the panoramic radiograph showed that most implants had been reabsorbed and replaced by new bone formation. All patients in this study had no recurrence of infection at 6 to 18 months (mean, 10.8 months) of follow-up. CONCLUSIONS: The use of vancomycin-impregnated calcium sulfate in the surgical debridement site for chronic osteomyelitis of the jaw has shown encouraging results. In addition, calcium sulfate can promote the formation of new bone to a certain extent.


Subject(s)
Calcium Sulfate/therapeutic use , Jaw Diseases/drug therapy , Osteomyelitis/drug therapy , Vancomycin/therapeutic use , Adolescent , Adult , Aged , Calcium Sulfate/administration & dosage , Debridement/adverse effects , Debridement/methods , Female , Humans , Jaw Diseases/surgery , Male , Middle Aged , Osteomyelitis/surgery , Treatment Outcome , Vancomycin/administration & dosage , Wound Healing/drug effects , Young Adult
14.
J Oral Maxillofac Surg ; 75(2): 436.e1-436.e10, 2017 Feb.
Article in English | MEDLINE | ID: mdl-27837651

ABSTRACT

PURPOSE: Maxillomandibular ossifying fibroma is a benign tumor that affects young adults. Complete excision can allow satisfactory management with no recurrence. During a humanitarian mission, one is confronted with many types of damage from these fibromas. Their management requires wide resection (mandibulectomy interrupter or maxillectomy) and free flap reconstruction. However, technical conditions during a humanitarian mission might not allow the performance of a free flap reconstruction. How can such patients be managed? Should these patients receive a straightforward intervention performed on site during the mission or should they go to another country with a technical platform suitable for microsurgical reconstruction? PATIENTS AND METHODS: During a humanitarian mission in Ouagadougou, Burkina Faso, 6 patients with large ossifying fibromas traveled to France to undergo wide excision of the lesion and free flap reconstruction using the fibula. The Enfants du Noma paid for the travel and medical costs. RESULTS: No flap was lost. Four patients (67%) had local (disunity of scar or local infection) or general (malaria) complications that quickly resolved. CONCLUSIONS: Most teams agree that free flaps should not be performed during humanitarian missions, and only 1 German team practices in Sokoto, Nigeria. Therefore, medical travel is an attractive solution that allows optimal management and requires financial assistance from humanitarian organizations.


Subject(s)
Bone Diseases, Developmental/surgery , Jaw Diseases/surgery , Adolescent , Adult , Bone Diseases, Developmental/diagnostic imaging , Bone Diseases, Developmental/pathology , Burkina Faso , Child , Humans , Jaw Diseases/diagnostic imaging , Jaw Diseases/pathology , Male , Mandibular Diseases/diagnostic imaging , Mandibular Diseases/pathology , Mandibular Diseases/surgery , Mandibular Reconstruction/methods , Maxillary Diseases/diagnostic imaging , Maxillary Diseases/pathology , Maxillary Diseases/surgery , Medical Missions , Tomography, X-Ray Computed , Young Adult
15.
Med Oral Patol Oral Cir Bucal ; 22(6): e788-e795, 2017 Nov 01.
Article in English | MEDLINE | ID: mdl-29053660

ABSTRACT

BACKGROUND: Non-surgical treatment has generally been recommended for stage II medication-related osteonecrosis of the jaw (MRONJ) in preference to surgery. However, non-surgical treatment is not empirically effective. The aim of this study was to evaluate whether surgical or non-surgical treatment leads to better outcomes for stage II MRONJ. MATERIAL AND METHODS: In this retrospective study, surgery was performed in a total of 28 patients while 24 patients underwent non-surgical treatment. The outcomes of both treatment approaches after 6 months were evaluated and statistically compared. In addition, risk factors for surgical and non-surgical treatments were assessed for each. RESULTS: Surgical treatment in 25 patients (89.3%) resulted in success, with failure in 3 patients (10.7%). Non-surgical treatment was successful for 8 patients (33.3%) and failed in 16 patients (66.7%). There was therefore a significant difference between surgical and non-surgical treatment outcomes (P<0.01). Regarding risk factors, in non-surgical treatment primary diseases, medications, and drug holiday had a significant effect on outcomes (P<0.01). Risk factors for surgical treatment could not be clarified. CONCLUSIONS: Surgical treatment is more effective than non-surgical treatment for stage II MRONJ, and drug holiday, primary disease, and medication constitute risk factors in non-surgical treatment.


Subject(s)
Jaw Diseases/chemically induced , Jaw Diseases/therapy , Osteonecrosis/chemically induced , Osteonecrosis/therapy , Aged , Aged, 80 and over , Female , Humans , Jaw Diseases/surgery , Male , Osteonecrosis/surgery , Retrospective Studies , Risk Factors , Treatment Outcome
16.
Med Oral Patol Oral Cir Bucal ; 22(1): e64-e69, 2017 Jan 01.
Article in English | MEDLINE | ID: mdl-27918745

ABSTRACT

BACKGROUND: Jaw pseudocysts are benign osseous lesions of unclear etiology. Among these, the simple bone cyst (SBC) and aneurysmal bone cyst (ABC) are intriguing bone pathologies still rarely studied together. This retrospective study aimed to present the long-term case series of patients with jaw pseudocysts focusing on the clinical, radiographic, and transoperative aspects. MATERIAL AND METHODS: A retrospective case series of patients with SBC and ABC was performed. Clinical, radiographic, and transoperative aspects of both pseudocysts were reviewed from the histopathological archives of 20,469 cases between 1959-2012. All descriptive data were summarized. RESULTS: Of 354 (15.25%) bone pathologies, 54 cases of jaw pseudocysts were found, with 42 (11.86%) SBC and 12 (3.39%) ABC cases. For both lesions, most of the sample were young Caucasian women with an asymptomatic posterior mandible lesion with undetermined time of evolution and none trauma history. A unique radiolucent scalloped lesion presenting an empty cavity were also observed for both conditions. However, some atypical findings were found for SBC including: the expansion of bone cortical, tooth resorption, displacement of the mandibular canal, and recurrence. The absence of painful symptoms and the lack of classical blood-filled cavity were observed in some cases of ABC. CONCLUSIONS: The SBC and ABC are bone pathologies with few retrospective studies, no previous studies on the two conditions, varied nomenclature, and atypical aspects in some cases. Therefore, the knowledge of clinical, imaging, and transoperative features of such pseudocysts are clinically valuable as diagnosis hypothesis of radiolucent lesions of the jaws.


Subject(s)
Bone Cysts , Jaw Diseases , Adolescent , Adult , Aged , Bone Cysts/diagnosis , Bone Cysts/epidemiology , Bone Cysts/surgery , Bone Cysts, Aneurysmal/diagnosis , Bone Cysts, Aneurysmal/epidemiology , Bone Cysts, Aneurysmal/surgery , Brazil , Child , Female , Humans , Jaw Diseases/diagnosis , Jaw Diseases/epidemiology , Jaw Diseases/surgery , Male , Middle Aged , Retrospective Studies , Time Factors , Young Adult
17.
Clin Calcium ; 27(10): 1435-1443, 2017.
Article in Japanese | MEDLINE | ID: mdl-28947695

ABSTRACT

Surgical orthodontic treatments for patients with facial deformities are performed to improve the occlusal abnormalities and facial deformities caused by skeletal and dental problems such as deformation and disharmony of the upper and lower jaws, crowding, and excessive tooth axis inclination. Such treatments were performed under close and detailed coordination between orthodontists and oral surgeons. The oral maxillofacial region plays an important role in daily life functions such as mastication, respiration, and speech. Surgical orthodontic treatment is very helpful and effective in improving both dysfunctions and dismorphologies in the patients with facial deformity. To make a diagnosis and draw up a treatment plan for surgical orthodontics, it is important to estimate the skeletal and dental morphological abnormality and/or disharmony in individual patients accurately.


Subject(s)
Jaw Diseases/surgery , Body Patterning , Humans , Orthodontic Appliances , Orthodontics, Corrective
18.
J Oral Maxillofac Surg ; 74(8): 1584-95, 2016 Aug.
Article in English | MEDLINE | ID: mdl-27000409

ABSTRACT

Osteopetrosis is a generic term for generalized sclerotic conditions caused by rare genetic disorders. Decreased osteoclastic activities disturb bone remodeling, resulting in greater mineral density and greater compressive strength; therefore, bone fracture is a major physical symptom of osteopetrosis. Osteomyelitis of the maxilla or mandible is a common and well-documented complication of osteopetrosis. Local infection, such as odontogenic infection, is more likely to lead to osteomyelitis, and treatment strategies can be challenging. However, detailed ultrastructural analyses of bone from patients with osteopetrosis and odontogenic infection are limited. This report describes a case of osteomyelitis of the maxilla and mandible secondary to osteopetrosis in an adult patient and presents ultrastructural data of alveolar bone tissue analyzed by contact microradiography, electron probe microanalysis, and x-ray diffraction. Cases of osteomyelitis of the jaw secondary to osteopetrosis also are reviewed.


Subject(s)
Alveolar Process/pathology , Jaw Diseases/diagnosis , Jaw Diseases/etiology , Osteomyelitis/etiology , Osteopetrosis/complications , Combined Modality Therapy , Diagnosis, Differential , Humans , Jaw Diseases/drug therapy , Jaw Diseases/surgery , Male , Middle Aged , Osteomyelitis/drug therapy , Osteomyelitis/surgery , Osteopetrosis/drug therapy , Osteopetrosis/surgery , Radiography, Panoramic
19.
J Oral Maxillofac Surg ; 74(6): 1153-8, 2016 Jun.
Article in English | MEDLINE | ID: mdl-26850870

ABSTRACT

PURPOSE: Idiopathic bone cavities (IBCs) are benign osseous pseudocysts of unclear etiology. Their clinical course and response to treatment are poorly understood. The purpose of this study was to present a case series of patients with IBC with long-term follow-up. PATIENTS AND METHODS: A retrospective case series of patients with IBC of the jaw was implemented. Medical records were reviewed for data on presentation and imaging. All patients underwent surgical exploration to confirm the diagnosis. Follow-up radiographs were evaluated for resolution or persistence after the procedure. Descriptive data were summarized. RESULTS: The sample included 45 patients (60% girls) with 47 IBCs who presented at a mean age of 13.5 ± 0.35 years (range, 9 to 17 yr). All lesions were asymptomatic and discovered as incidental findings; the average size was 2.0 cm (range, 0.8 to 7 cm). Most (n = 44) were solitary lesions of the mandible presenting within the body (n = 27), symphysis (n = 15), or ramus (n = 2). One patient had synchronous bilateral mandibular and maxillary IBCs. Common radiographic features included scalloping without root resorption or displacement and cortical thinning without expansion or perforation. Intraoperative findings showed an empty bone cavity often filled with blood-tinged serous fluid or blood. The histopathology of scrapings from the bony wall showed benign mixed fibrous tissue and no epithelial lining. Average radiographic follow-up was 32.7 ± 6.7 months (range, 0 to 9 yr). After exploration and curettage, 43% of patients had complete bone fill within 2 to 5 years. The other 57% had no change in lesion size at an average of 2.25 years (range, 2 to 9 yr). No patients developed symptoms, had enlargement of the lesion, or had pathologic fracture. CONCLUSION: Many IBCs persist for years despite exploration and curettage. Nonetheless, unresolved lesions did not enlarge or cause harm. A single procedure to confirm the diagnosis is sufficient for management.


Subject(s)
Jaw Diseases/diagnosis , Adolescent , Child , Female , Humans , Incidental Findings , Jaw Diseases/diagnostic imaging , Jaw Diseases/surgery , Male , Mandibular Diseases/diagnosis , Mandibular Diseases/diagnostic imaging , Mandibular Diseases/surgery , Maxillary Diseases/diagnosis , Maxillary Diseases/diagnostic imaging , Maxillary Diseases/surgery , Radiography, Panoramic , Retrospective Studies
20.
Kyobu Geka ; 69(6): 457-9, 2016 Jun.
Article in Japanese | MEDLINE | ID: mdl-27246131

ABSTRACT

A 47-year-old man was admitted to the emergency room, half a day after having fallen down on his right cheek drunkenly onto a concrete block. Physical examination revealed that the contusion was limited to the right side of his face, only around the cheek, without trauma to the neck, chest or abdomen. But wide ranging tactile crepitus with severe swelling was present on his face and neck due to widely spread emphysema. Computed tomography (CT) scan revealed some fractures of maxillary antrum, facial and cervical emphysema spreading to the lower part of mediastinum. After a conservative treatment, he recovered without any severe systematic complication. It was found that the facial and cervical emphysema and pneumomediastimum completely disappeared on the follow-up CT scan, 18 days after the event.


Subject(s)
Jaw Diseases/surgery , Maxillary Sinus/surgery , Mediastinal Emphysema/surgery , Skull Fractures/surgery , Humans , Jaw Diseases/complications , Jaw Diseases/diagnostic imaging , Male , Maxillary Sinus/diagnostic imaging , Mediastinal Emphysema/diagnostic imaging , Middle Aged , Skull Fractures/complications , Skull Fractures/diagnostic imaging , Tomography, X-Ray Computed , Treatment Outcome
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