Use of continuous venovenous hemodiafiltration in a case of severe phenobarbital poisoning.

Conventional hemodialysis and hemoperfusion have been used for life-threatening phenobarbital poisoning. We report the successful use of continuous renal replacement therapy in a case of severe phenobarbital poisoning associated with severe coma and hypotension. Use of this modality led to clearance of phenobarbital with improvement in the clinical status of the patient.