Búsqueda | BVS CLAP/SMR-OPS/OMS

1.

Post-translational insertion of boron in proteins to probe and modulate function.

Mollner, Tim A; Isenegger, Patrick G; Josephson, Brian; Buchanan, Charles; Lercher, Lukas; Oehlrich, Daniel; Hansen, D Flemming; Mohammed, Shabaz; Baldwin, Andrew J; Gouverneur, Véronique; Davis, Benjamin G.

Nat Chem Biol ; 17(12): 1245-1261, 2021 12.

Artículo en Inglés | MEDLINE | ID: mdl-34725511

2.

Towards autonomous analysis of chemical exchange saturation transfer experiments using deep neural networks.

Karunanithy, Gogulan; Yuwen, Tairan; Kay, Lewis E; Hansen, D Flemming.

J Biomol NMR ; 76(3): 75-86, 2022 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-35622310

3.

Virtual Homonuclear Decoupling in Direct Detection Nuclear Magnetic Resonance Experiments Using Deep Neural Networks.

Karunanithy, Gogulan; Mackenzie, Harold W; Hansen, D Flemming.

J Am Chem Soc ; 143(41): 16935-16942, 2021 10 20.

Artículo en Inglés | MEDLINE | ID: mdl-34633815

4.

FID-Net: A versatile deep neural network architecture for NMR spectral reconstruction and virtual decoupling.

Karunanithy, Gogulan; Hansen, D Flemming.

J Biomol NMR ; 75(4-5): 179-191, 2021 May.

Artículo en Inglés | MEDLINE | ID: mdl-33870472

5.

Potent non-hydroxamate inhibitors of histone deacetylase-8: Role and scope of an isoindolin-2-yl linker with an α-amino amide as the zinc-binding unit.

Greenwood, Simon O R; Chan, A W Edith; Hansen, D Flemming; Marson, Charles M.

Bioorg Med Chem Lett ; 30(5): 126926, 2020 03 01.

Artículo en Inglés | MEDLINE | ID: mdl-31952961

6.

Publisher Correction: Post-translational insertion of boron in proteins to probe and modulate function.

Mollner, Tim A; Isenegger, Patrick G; Josephson, Brian; Buchanan, Charles; Lercher, Lukas; Oehlrich, Daniel; Hansen, D Flemming; Mohammed, Shabaz; Baldwin, Andrew J; Gouverneur, Véronique; Davis, Benjamin G.

Nat Chem Biol ; 18(1): 116, 2022 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-34903852

7.

Structural mass spectrometry decodes domain interaction and dynamics of the full-length Human Histone Deacetylase 2.

Soloviev, Zoja; Bullock, Joshua M A; James, Juliette M B; Sauerwein, Andrea C; Nettleship, Joanne E; Owens, Raymond J; Hansen, D Flemming; Topf, Maya; Thalassinos, Konstantinos.

Biochim Biophys Acta Proteins Proteom ; 1870(3): 140759, 2022 03 01.

Artículo en Inglés | MEDLINE | ID: mdl-35051665

8.

Structures of invisible, excited protein states by relaxation dispersion NMR spectroscopy.

Vallurupalli, Pramodh; Hansen, D Flemming; Kay, Lewis E.

Proc Natl Acad Sci U S A ; 105(33): 11766-71, 2008 Aug 19.

Artículo en Inglés | MEDLINE | ID: mdl-18701719

9.

Methodological advancements for characterising protein side chains by NMR spectroscopy.

Karunanithy, Gogulan; Shukla, Vaibhav Kumar; Hansen, D Flemming.

Curr Opin Struct Biol ; 70: 61-69, 2021 10.

Artículo en Inglés | MEDLINE | ID: mdl-33989947

10.

Aromatic side-chain flips orchestrate the conformational sampling of functional loops in human histone deacetylase 8.

Shukla, Vaibhav Kumar; Siemons, Lucas; Gervasio, Francesco L; Hansen, D Flemming.

Chem Sci ; 12(27): 9318-9327, 2021 Jul 14.

Artículo en Inglés | MEDLINE | ID: mdl-34349901

11.

The anatomy of unfolding of Yfh1 is revealed by site-specific fold stability analysis measured by 2D NMR spectroscopy.

Puglisi, Rita; Karunanithy, Gogulan; Hansen, D Flemming; Pastore, Annalisa; Temussi, Piero Andrea.

Commun Chem ; 4(1)2021 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-35243007

12.

Measurement of bond vector orientations in invisible excited states of proteins.

Vallurupalli, Pramodh; Hansen, D Flemming; Stollar, Elliott; Meirovitch, Eva; Kay, Lewis E.

Proc Natl Acad Sci U S A ; 104(47): 18473-7, 2007 Nov 20.

Artículo en Inglés | MEDLINE | ID: mdl-18006656

13.

Multiquantum Chemical Exchange Saturation Transfer NMR to Quantify Symmetrical Exchange: Application to Rotational Dynamics of the Guanidinium Group in Arginine Side Chains.

Karunanithy, Gogulan; Reinstein, Jochen; Hansen, D Flemming.

J Phys Chem Lett ; 11(14): 5649-5654, 2020 Jul 16.

Artículo en Inglés | MEDLINE | ID: mdl-32543198

14.

A distal regulatory region of a class I human histone deacetylase.

Werbeck, Nicolas D; Shukla, Vaibhav Kumar; Kunze, Micha B A; Yalinca, Havva; Pritchard, Ruth B; Siemons, Lucas; Mondal, Somnath; Greenwood, Simon O R; Kirkpatrick, John; Marson, Charles M; Hansen, D Flemming.

Nat Commun ; 11(1): 3841, 2020 07 31.

Artículo en Inglés | MEDLINE | ID: mdl-32737323

15.

Mechanism of Crosstalk between the LSD1 Demethylase and HDAC1 Deacetylase in the CoREST Complex.

Song, Yun; Dagil, Lisbeth; Fairall, Louise; Robertson, Naomi; Wu, Mingxuan; Ragan, T J; Savva, Christos G; Saleh, Almutasem; Morone, Nobuhiro; Kunze, Micha B A; Jamieson, Andrew G; Cole, Philip A; Hansen, D Flemming; Schwabe, John W R.

Cell Rep ; 30(8): 2699-2711.e8, 2020 02 25.

Artículo en Inglés | MEDLINE | ID: mdl-32101746

16.

Interaction Between the a3 Region of Factor VIII and the TIL'E' Domains of the von Willebrand Factor.

Dagil, Lisbeth; Troelsen, Kathrin S; Bolt, Gert; Thim, Lars; Wu, Bo; Zhao, Xin; Tuddenham, Edward G D; Nielsen, Thomas E; Tanner, David A; Faber, Johan H; Breinholt, Jens; Rasmussen, Jakob E; Hansen, D Flemming.

Biophys J ; 117(3): 479-489, 2019 08 06.

Artículo en Inglés | MEDLINE | ID: mdl-31349985

17.

Measurement of methyl group motional parameters of invisible, excited protein states by NMR spectroscopy.

Hansen, D Flemming; Vallurupalli, Pramodh; Kay, Lewis E.

J Am Chem Soc ; 131(35): 12745-54, 2009 Sep 09.

Artículo en Inglés | MEDLINE | ID: mdl-19685870

18.

Accurate measurement of alpha proton chemical shifts of excited protein states by relaxation dispersion NMR spectroscopy.

Lundström, Patrik; Hansen, D Flemming; Vallurupalli, Pramodh; Kay, Lewis E.

J Am Chem Soc ; 131(5): 1915-26, 2009 Feb 11.

Artículo en Inglés | MEDLINE | ID: mdl-19152327

19.

Measurement of methyl axis orientations in invisible, excited states of proteins by relaxation dispersion NMR spectroscopy.

Baldwin, Andrew J; Hansen, D Flemming; Vallurupalli, Pramodh; Kay, Lewis E.

J Am Chem Soc ; 131(33): 11939-48, 2009 Aug 26.

Artículo en Inglés | MEDLINE | ID: mdl-19627152

20.

Selective characterization of microsecond motions in proteins by NMR relaxation.

Hansen, D Flemming; Feng, Haniqiao; Zhou, Zheng; Bai, Yawen; Kay, Lewis E.

J Am Chem Soc ; 131(44): 16257-65, 2009 Nov 11.

Artículo en Inglés | MEDLINE | ID: mdl-19842628

BVS CLAP/SMR-OPS/OMS

Centro Latinoamericano de Perinatología, Salud de la Mujer y Reproductiva

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