Búsqueda | BVS CLAP/SMR-OPS/OMS

1.

Th17 cell master transcription factor RORC2 regulates HIV-1 gene expression and viral outgrowth.

Wiche Salinas, Tomas Raul; Zhang, Yuwei; Sarnello, Daniele; Zhyvoloup, Alexander; Marchand, Laurence Raymond; Fert, Augustine; Planas, Delphine; Lodha, Manivel; Chatterjee, Debashree; Karwacz, Katarzyna; Oxenford, Sally; Routy, Jean-Pierre; Irlbeck, David; Amrine-Madsen, Heather; Ancuta, Petronela; Fassati, Ariberto.

Proc Natl Acad Sci U S A ; 118(48)2021 11 30.

Artículo en Inglés | MEDLINE | ID: mdl-34819367

2.

Analysis of Baboon IAPP Provides Insight into Amyloidogenicity and Cytotoxicity of Human IAPP.

Ridgway, Zachary; Lee, Kyung-Hoon; Zhyvoloup, Alexander; Wong, Amy; Eldrid, Charles; Hannaberry, Eleni; Thalassinos, Konstantinos; Abedini, Andisheh; Raleigh, Daniel P.

Biophys J ; 118(5): 1142-1151, 2020 03 10.

Artículo en Inglés | MEDLINE | ID: mdl-32105649

3.

Analysis of Prairie Vole Amylin Reveals the Importance of the N-Terminus and Residue 22 in Amyloidogenicity and Cytotoxicity.

Lee, Kyung-Hoon; Noh, Daeun; Zhyvoloup, Alexander; Raleigh, Daniel.

Biochemistry ; 59(4): 471-478, 2020 02 04.

Artículo en Inglés | MEDLINE | ID: mdl-31777253

4.

Analysis of Proline Substitutions Reveals the Plasticity and Sequence Sensitivity of Human IAPP Amyloidogenicity and Toxicity.

Ridgway, Zachary; Eldrid, Charles; Zhyvoloup, Alexander; Ben-Younis, Aisha; Noh, Daeun; Thalassinos, Konstantinos; Raleigh, Daniel P.

Biochemistry ; 59(6): 742-754, 2020 02 18.

Artículo en Inglés | MEDLINE | ID: mdl-31922743

5.

Analysis of Amylin Consensus Sequences Suggests That Human Amylin Is Not Optimized to Minimize Amyloid Formation and Provides Clues to Factors That Modulate Amyloidogenicity.

Noh, Daeun; Bower, Rebekah L; Hay, Debbie L; Zhyvoloup, Alexander; Raleigh, Daniel P.

ACS Chem Biol ; 15(6): 1408-1416, 2020 06 19.

Artículo en Inglés | MEDLINE | ID: mdl-32364695

6.

Analysis of disulphide bond linkage between CoA and protein cysteine thiols during sporulation and in spores of Bacillus species.

Zhyvoloup, Alexander; Yu, Bess Yi Kun; Bakovic, Jovana; Davis-Lunn, Mathew; Tossounian, Maria-Armineh; Thomas, Naam; Tsuchiya, Yugo; Peak-Chew, Sew Yeu; Wigneshweraraj, Sivaramesh; Filonenko, Valeriy; Skehel, Mark; Setlow, Peter; Gout, Ivan.

FEMS Microbiol Lett ; 367(23)2020 12 22.

Artículo en Inglés | MEDLINE | ID: mdl-33206970

7.

Covalent Aurora A regulation by the metabolic integrator coenzyme A.

Tsuchiya, Yugo; Byrne, Dominic P; Burgess, Selena G; Bormann, Jenny; Bakovic, Jovana; Huang, Yueyang; Zhyvoloup, Alexander; Yu, Bess Yi Kun; Peak-Chew, Sew; Tran, Trang; Bellany, Fiona; Tabor, Alethea B; Chan, Aw Edith; Guruprasad, Lalitha; Garifulin, Oleg; Filonenko, Valeriy; Vonderach, Matthias; Ferries, Samantha; Eyers, Claire E; Carroll, John; Skehel, Mark; Bayliss, Richard; Eyers, Patrick A; Gout, Ivan.

Redox Biol ; 28: 101318, 2020 01.

Artículo en Inglés | MEDLINE | ID: mdl-31546169

8.

Coenzyme A and protein CoAlation levels are regulated in response to oxidative stress and during morphogenesis in Dictyostelium discoideum.

Aloum, Lujain; Brimson, Christopher A; Zhyvoloup, Alexander; Baines, Robert; Bakovic, Jovana; Filonenko, Valeriy; Thompson, Christopher R L; Gout, Ivan.

Biochem Biophys Res Commun ; 511(2): 294-299, 2019 04 02.

Artículo en Inglés | MEDLINE | ID: mdl-30797553

9.

Digoxin reveals a functional connection between HIV-1 integration preference and T-cell activation.

Zhyvoloup, Alexander; Melamed, Anat; Anderson, Ian; Planas, Delphine; Lee, Chen-Hsuin; Kriston-Vizi, Janos; Ketteler, Robin; Merritt, Andy; Routy, Jean-Pierre; Ancuta, Petronela; Bangham, Charles R M; Fassati, Ariberto.

PLoS Pathog ; 13(7): e1006460, 2017 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-28727807

10.

Protein CoAlation and antioxidant function of coenzyme A in prokaryotic cells.

Tsuchiya, Yugo; Zhyvoloup, Alexander; Bakovic, Jovana; Thomas, Naam; Yu, Bess Yi Kun; Das, Sayoni; Orengo, Christine; Newell, Clare; Ward, John; Saladino, Giorgio; Comitani, Federico; Gervasio, Francesco L; Malanchuk, Oksana M; Khoruzhenko, Antonina I; Filonenko, Valeriy; Peak-Chew, Sew Yeu; Skehel, Mark; Gout, Ivan.

Biochem J ; 475(11): 1909-1937, 2018 06 06.

Artículo en Inglés | MEDLINE | ID: mdl-29626155

11.

Protein CoAlation: a redox-regulated protein modification by coenzyme A in mammalian cells.

Tsuchiya, Yugo; Peak-Chew, Sew Yeu; Newell, Clare; Miller-Aidoo, Sheritta; Mangal, Sriyash; Zhyvoloup, Alexander; Bakovic, Jovana; Malanchuk, Oksana; Pereira, Gonçalo C; Kotiadis, Vassilios; Szabadkai, Gyorgy; Duchen, Michael R; Campbell, Mark; Cuenca, Sergio Rodriguez; Vidal-Puig, Antonio; James, Andrew M; Murphy, Michael P; Filonenko, Valeriy; Skehel, Mark; Gout, Ivan.

Biochem J ; 474(14): 2489-2508, 2017 07 11.

Artículo en Inglés | MEDLINE | ID: mdl-28341808

12.

Heat shock protein 90 controls HIV-1 reactivation from latency.

Anderson, Ian; Low, Jun Siong; Weston, Stuart; Weinberger, Michael; Zhyvoloup, Alexander; Labokha, Aksana A; Corazza, Gianmarco; Kitson, Russell A; Moody, Christopher J; Marcello, Alessandro; Fassati, Ariberto.

Proc Natl Acad Sci U S A ; 111(15): E1528-37, 2014 Apr 15.

Artículo en Inglés | MEDLINE | ID: mdl-24706778

13.

Amyloidogenicity and cytotoxicity of des-Lys-1 human amylin provides insight into amylin self-assembly and highlights the difficulties of defining amyloidogenicity.

Lee, Kyung-Hoon; Zhyvoloup, Alexander; Raleigh, Daniel.

Protein Eng Des Sel ; 32(2): 87-93, 2019 12 13.

Artículo en Inglés | MEDLINE | ID: mdl-31768548

14.

The triphenylmethane dye brilliant blue G is only moderately effective at inhibiting amyloid formation by human amylin or at disaggregating amylin amyloid fibrils, but interferes with amyloid assays; Implications for inhibitor design.

Akter, Rehana; Zhyvoloup, Alexander; Zheng, Bingqian; Bhatia, Surita R; Raleigh, Daniel P.

PLoS One ; 14(8): e0219130, 2019.

Artículo en Inglés | MEDLINE | ID: mdl-31404073

15.

Biological properties of potent inhibitors of class I phosphatidylinositide 3-kinases: from PI-103 through PI-540, PI-620 to the oral agent GDC-0941.

Raynaud, Florence I; Eccles, Suzanne A; Patel, Sonal; Alix, Sonia; Box, Gary; Chuckowree, Irina; Folkes, Adrian; Gowan, Sharon; De Haven Brandon, Alexis; Di Stefano, Francesca; Hayes, Angela; Henley, Alan T; Lensun, Letitia; Pergl-Wilson, Giles; Robson, Anthony; Saghir, Nahid; Zhyvoloup, Alexander; McDonald, Edward; Sheldrake, Peter; Shuttleworth, Stephen; Valenti, Melanie; Wan, Nan Chi; Clarke, Paul A; Workman, Paul.

Mol Cancer Ther ; 8(7): 1725-38, 2009 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-19584227

16.

Protein kinase C phosphorylates ribosomal protein S6 kinase betaII and regulates its subcellular localization.

Valovka, Taras; Verdier, Frederique; Cramer, Rainer; Zhyvoloup, Alexander; Fenton, Timothy; Rebholz, Heike; Wang, Mong-Lien; Gzhegotsky, Miechyslav; Lutsyk, Alexander; Matsuka, Genadiy; Filonenko, Valeriy; Wang, Lijun; Proud, Christopher G; Parker, Peter J; Gout, Ivan T.

Mol Cell Biol ; 23(3): 852-63, 2003 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-12529391

17.

Specific interaction between S6K1 and CoA synthase: a potential link between the mTOR/S6K pathway, CoA biosynthesis and energy metabolism.

Nemazanyy, Ivan; Panasyuk, Ganna; Zhyvoloup, Alexander; Panayotou, George; Gout, Ivan T; Filonenko, Valeriy.

FEBS Lett ; 578(3): 357-62, 2004 Dec 17.

Artículo en Inglés | MEDLINE | ID: mdl-15589845

18.

EDC4 interacts with and regulates the dephospho-CoA kinase activity of CoA synthase.

Gudkova, Daria; Panasyuk, Ganna; Nemazanyy, Ivan; Zhyvoloup, Alexander; Monteil, Pascale; Filonenko, Valeriy; Gout, Ivan.

FEBS Lett ; 586(20): 3590-5, 2012 Oct 19.

Artículo en Inglés | MEDLINE | ID: mdl-22982864

19.

Large-scale yeast transformation in low-percentage agarose medium.

Panasyuk, Ganna; Nemazanyy, Ivan; Filonenko, Valeriy; Zhyvoloup, Alexander.

Biotechniques ; 36(1): 40-2, 44, 2004 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-14740481

20.

The identification of 2-(1H-indazol-4-yl)-6-(4-methanesulfonyl-piperazin-1-ylmethyl)-4-morpholin-4-yl-thieno[3,2-d]pyrimidine (GDC-0941) as a potent, selective, orally bioavailable inhibitor of class I PI3 kinase for the treatment of cancer .

Folkes, Adrian J; Ahmadi, Khatereh; Alderton, Wendy K; Alix, Sonia; Baker, Stewart J; Box, Gary; Chuckowree, Irina S; Clarke, Paul A; Depledge, Paul; Eccles, Suzanne A; Friedman, Lori S; Hayes, Angela; Hancox, Timothy C; Kugendradas, Arumugam; Lensun, Letitia; Moore, Pauline; Olivero, Alan G; Pang, Jodie; Patel, Sonal; Pergl-Wilson, Giles H; Raynaud, Florence I; Robson, Anthony; Saghir, Nahid; Salphati, Laurent; Sohal, Sukhjit; Ultsch, Mark H; Valenti, Melanie; Wallweber, Heidi J A; Wan, Nan Chi; Wiesmann, Christian; Workman, Paul; Zhyvoloup, Alexander; Zvelebil, Marketa J; Shuttleworth, Stephen J.

J Med Chem ; 51(18): 5522-32, 2008 Sep 25.

Artículo en Inglés | MEDLINE | ID: mdl-18754654

BVS CLAP/SMR-OPS/OMS

Centro Latinoamericano de Perinatología, Salud de la Mujer y Reproductiva

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