Detalhe da pesquisa
1.
Three-stage model of helical membrane protein folding: Role of membrane-water interface as the intermediate stage vestibule for TM helices during their in membrano assembly.
Biochem Biophys Res Commun
; 624: 1-7, 2022 10 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35926384
2.
HER3-targeted protein chimera forms endosomolytic capsomeres and self-assembles into stealth nucleocapsids for systemic tumor homing of RNA interference in vivo.
Nucleic Acids Res
; 47(21): 11020-11043, 2019 12 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31617560
3.
Pseudo-Symmetric Assembly of Protodomains as a Common Denominator in the Evolution of Polytopic Helical Membrane Proteins.
J Mol Evol
; 88(4): 319-344, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32189026
4.
Activation mechanism of the G protein-coupled sweet receptor heterodimer with sweeteners and allosteric agonists.
Proc Natl Acad Sci U S A
; 114(10): 2568-2573, 2017 03 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28228527
5.
Predicting glycosaminoglycan surface protein interactions and implications for studying axonal growth.
Proc Natl Acad Sci U S A
; 114(52): 13697-13702, 2017 12 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-29229841
6.
Antifreeze proteins govern the precipitation of trehalose in a freezing-avoiding insect at low temperature.
Proc Natl Acad Sci U S A
; 113(24): 6683-8, 2016 06 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-27226297
7.
Understanding G Protein Selectivity of Muscarinic Acetylcholine Receptors Using Computational Methods.
Int J Mol Sci
; 20(21)2019 Oct 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-31653051
8.
Structure-Based Sequence Alignment of the Transmembrane Domains of All Human GPCRs: Phylogenetic, Structural and Functional Implications.
PLoS Comput Biol
; 12(3): e1004805, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-27028541
9.
Ligand- and mutation-induced conformational selection in the CCR5 chemokine G protein-coupled receptor.
Proc Natl Acad Sci U S A
; 111(36): 13040-5, 2014 Sep 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-25157173
10.
SuperBiHelix method for predicting the pleiotropic ensemble of G-protein-coupled receptor conformations.
Proc Natl Acad Sci U S A
; 111(1): E72-8, 2014 Jan 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-24344284
11.
Conformational and Thermodynamic Landscape of GPCR Activation from Theory and Computation.
Biophys J
; 110(12): 2618-2629, 2016 Jun 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-27332120
12.
A bitter pill for type 2 diabetes? The activation of bitter taste receptor TAS2R38 can stimulate GLP-1 release from enteroendocrine L-cells.
Biochem Biophys Res Commun
; 475(3): 295-300, 2016 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27208775
13.
Computational Prediction and Biochemical Analyses of New Inverse Agonists for the CB1 Receptor.
J Chem Inf Model
; 56(1): 201-12, 2016 Jan 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-26633590
14.
The interaction of N-glycans in Fcγ receptor I α-chain with Escherichia coli K1 outer membrane protein A for entry into macrophages: experimental and computational analysis.
J Biol Chem
; 289(45): 30937-49, 2014 Nov 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-25231998
15.
Predicted structure of agonist-bound glucagon-like peptide 1 receptor, a class B G protein-coupled receptor.
Proc Natl Acad Sci U S A
; 109(49): 19988-93, 2012 Dec 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-23169631
16.
Use of G-protein-coupled and -uncoupled CCR5 receptors by CCR5 inhibitor-resistant and -sensitive human immunodeficiency virus type 1 variants.
J Virol
; 87(12): 6569-81, 2013 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-23468486
17.
Elucidating glycosaminoglycan-protein-protein interactions using carbohydrate microarray and computational approaches.
Proc Natl Acad Sci U S A
; 108(24): 9747-52, 2011 Jun 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-21628576
18.
Identification of Gα12-vs-Gα13-coupling determinants and development of a Gα12/13-coupled designer GPCR.
Sci Rep
; 14(1): 11119, 2024 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38750247
19.
Towards a structural and functional analysis of the immunoglobulin-fold proteome.
Adv Protein Chem Struct Biol
; 138: 135-178, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38220423
20.
Computationally-predicted CB1 cannabinoid receptor mutants show distinct patterns of salt-bridges that correlate with their level of constitutive activity reflected in G protein coupling levels, thermal stability, and ligand binding.
Proteins
; 81(8): 1304-17, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23408552