Detalhe da pesquisa
1.
The Bis(monoacylglycero)-phosphate Hypothesis: From Lysosomal Function to Therapeutic Avenues.
Annu Rev Biochem
; 2024 Apr 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38603559
2.
Physiologic Medium Rewires Cellular Metabolism and Reveals Uric Acid as an Endogenous Inhibitor of UMP Synthase.
Cell
; 169(2): 258-272.e17, 2017 Apr 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28388410
3.
mTORC1 Activator SLC38A9 Is Required to Efflux Essential Amino Acids from Lysosomes and Use Protein as a Nutrient.
Cell
; 171(3): 642-654.e12, 2017 Oct 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-29053970
4.
Glycerophosphodiesters inhibit lysosomal phospholipid catabolism in Batten disease.
Mol Cell
; 84(7): 1354-1364.e9, 2024 Apr 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-38447580
5.
An Essential Role of the Mitochondrial Electron Transport Chain in Cell Proliferation Is to Enable Aspartate Synthesis.
Cell
; 162(3): 540-51, 2015 Jul 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-26232224
6.
APOE4/4 is linked to damaging lipid droplets in Alzheimer's disease microglia.
Nature
; 628(8006): 154-161, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38480892
7.
R-loop-derived cytoplasmic RNA-DNA hybrids activate an immune response.
Nature
; 613(7942): 187-194, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36544021
8.
Sharing is caring: TMEM165 a Golgi calcium importer used by the lysosome.
Trends Biochem Sci
; 2024 May 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-38816278
9.
CLN3 is required for the clearance of glycerophosphodiesters from lysosomes.
Nature
; 609(7929): 1005-1011, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36131016
10.
Maintaining Iron Homeostasis Is the Key Role of Lysosomal Acidity for Cell Proliferation.
Mol Cell
; 77(3): 645-655.e7, 2020 02 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31983508
11.
Golgi-IP, a tool for multimodal analysis of Golgi molecular content.
Proc Natl Acad Sci U S A
; 120(20): e2219953120, 2023 05 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-37155866
12.
Author Correction: R-loop-derived cytoplasmic RNA-DNA hybrids activate an immune response.
Nature
; 626(7998): E6, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38263519
13.
Ferroptosis regulation by the NGLY1/NFE2L1 pathway.
Proc Natl Acad Sci U S A
; 119(11): e2118646119, 2022 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35271393
14.
Lysosomal cathepsin D mediates endogenous mucin glycodomain catabolism in mammals.
Proc Natl Acad Sci U S A
; 119(39): e2117105119, 2022 09 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-36122205
15.
Small molecule C381 targets the lysosome to reduce inflammation and ameliorate disease in models of neurodegeneration.
Proc Natl Acad Sci U S A
; 119(11): e2121609119, 2022 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35259016
16.
Carnitine octanoyltransferase is important for the assimilation of exogenous acetyl-L-carnitine into acetyl-CoA in mammalian cells.
J Biol Chem
; 299(2): 102848, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36587768
17.
CYP4F2 is a human-specific determinant of circulating N-acyl amino acid levels.
J Biol Chem
; 299(6): 104764, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37121548
18.
Histidine catabolism is a major determinant of methotrexate sensitivity.
Nature
; 559(7715): 632-636, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29995852
19.
Author Correction: High-fat diet enhances stemness and tumorigenicity of intestinal progenitors.
Nature
; 560(7717): E26, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29849139
20.
Author Correction: Histidine catabolism is a major determinant of methotrexate sensitivity.
Nature
; 602(7895): E17-E18, 2022 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-35017686