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1.
Surg Radiol Anat ; 43(7): 1117-1122, 2021 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-33416973

RESUMO

PURPOSE: The purpose of this study was to investigate if the anterolateral ligament of the knee (ALL) is present in the human fetus and describe its topography along with other structures of the region. METHODS: Forty human fetuses knee joints, at mean age 34 weeks (± 2.57 weeks), fixed in 10% formalin, were submitted to cross-sectional dissection and mesoscopic analysis. RESULTS: The ALL was not identified, although the usual topography of the region was identified in all specimens: skin, subcutaneous tissue, iliotibial tract (ITT), fibular collateral ligament, popliteal muscle tendon, lateral meniscus, patellar ligament, infrapatellar fat pad, lateral patellar retinaculum, knee joint capsule, lateral inferior genicular vessels, and the biceps femoris tendon. The ITT reveals anterior (n = 12) and lateral thickening (n = 17) in some specimens. This thickening was found in both knees of the same subject in 6/20 specimens. CONCLUSION: The anterolateral ligament of the knee is not a congenital or solid structure. Our results suggest that the ALL may be a deep layer of the ITT or part of the knee joint capsule, or its identification is evaluator dependent.


Assuntos
Desenvolvimento Fetal , Cápsula Articular/embriologia , Articulação do Joelho/embriologia , Ligamentos Articulares/embriologia , Anatomia Transversal , Cadáver , Dissecação , Feminino , Feto , Humanos , Masculino
2.
Connect Tissue Res ; 60(3): 230-239, 2019 05.
Artigo em Inglês | MEDLINE | ID: mdl-29929404

RESUMO

Extensive burn may cause acute resistance to insulin, which accentuates hypermetabolism, impairs glucose metabolism, immune dysfunction and risks of sepsis. To minimize these effects, insulin is used as a treatment. The purpose was to analyze the collagen-elastic arrangement effects of insulin on the burned skin. Wistar rats were assigned in groups: control (C); control with insulin (C + I); scald burn injury (SBI); and SBI with insulin (SBI+ I). SBI were submitted to 45% total body surface area burn and the insulin-treated groups received insulin (5 UI/Kg/day) for 4 or 14 days (d). Insulin levels, glucose tolerance test and HOMA index were determined. The skin sections were analyzed for histophatological and morphoquantitative data. Histopathological findings showed increased reepithelization of SBI+ I and formation of a new muscle layer after 14 days. In the collagen-elastic arrangement, insulin for 4 days increased the volume fraction (Vv) of thin collagen and elastic fibers. After 14 days, independently of injury, insulin decreased the elastic fibers. Insulin was able to reverse damages in the collagen-elastic rearrangement and stimulate reepithelization after 4 days. Untreated scald-burned animals showed higher Vv of thick collagen after 4 days, while those treated had a higher Vv of thin collagen. The Vv of elastic fibers was increased in SBI+ I for 4 days. In conclusion, insulin treatment was able to stimulate reepithelization. It also reversed the damages to the collagen-elastic arrangement in the scald-burned group, improving the organization of thin collagen and increasing the Vv of elastic fibers in the injured group treated with insulin for a short time, that is, for 4 days.


Assuntos
Queimaduras/tratamento farmacológico , Colágeno/metabolismo , Elastina/metabolismo , Insulina/uso terapêutico , Reepitelização , Animais , Área Sob a Curva , Peso Corporal , Queimaduras/patologia , Comportamento de Ingestão de Líquido , Comportamento Alimentar , Glucose/metabolismo , Insulina/farmacologia , Masculino , Ratos Wistar , Reepitelização/efeitos dos fármacos , Pele/efeitos dos fármacos , Pele/patologia
3.
Autops Case Rep ; 11: e2020239, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34307211

RESUMO

The gluteal region contains important neurovascular and muscular structures with diverse clinical and surgical implications. This paper aims to describe and discuss the clinical importance of a unique variation involving not only the piriformis, gluteus medius, gluteus minimus, obturator internus, and superior gemellus muscles, but also the superior gluteal neurovascular bundle, and sciatic nerve. A routine dissection of a right hemipelvis and its gluteal region of a male cadaver fixed in 10% formalin was performed. During dissection, it was observed a rare presentation of the absence of the piriformis muscle, associated with a tendon fusion between gluteus and obturator internus, and a fusion between gluteus minimus and superior gemellus muscles, along with an unusual topography with the sciatic nerve, which passed through these group of fused muscles. This rare variation stands out with clinical manifestations that are not fully established. Knowing this anatomy is essential to avoid surgical iatrogeny.

4.
Autops Case Rep ; 10(2): e2020151, 2020 Apr 23.
Artigo em Inglês | MEDLINE | ID: mdl-33344272

RESUMO

The authors describe a rare unilateral muscle variation in the thoracic wall combining the pectoralis quartus and chondro-epitrochlearis muscles. A routine dissection was performed in the upper right limb of a male adult cadaver with approximately 35-50 years of age, embalmed in formalin 10%. An accessory muscle, the pectoralis quartus, was identified and was associated with a tendon that was inserted in the medial humeral epicondyle, characteristic of the chondro-epitrochlearis muscle tendon. Such variations have significant clinical relevance to orthopedics, mastology, neural and vascular surgery, and other specialties, for surgical approaches in both the axillary and brachial regions.

5.
Autops Case Rep ; 10(4): e2020209, 2020 Sep 02.
Artigo em Inglês | MEDLINE | ID: mdl-33344324

RESUMO

The median artery is usually a transient vessel during the embryonic period. However, this artery can persist in adult life as the persistent median artery. This paper aims to describe this relevant anatomical variation for surgeons, review the literature and discuss its clinical implications. A routine dissection was performed in the upper left limb of a male adult cadaver of approximately 50-60 years of age, embalmed in formalin 10%. The persistent median artery was identified emerging as a terminal branch of the common interosseous artery with a path along the ulnar side of the median nerve. In the wrist, the persistent median artery passed through the carpal tunnel, deep in the transverse carpal ligament. The dissection in the palmar region revealed no anastomosis with the ulnar artery forming the superficial palmar arch. The common digital arteries emerged from the ulnar artery and the persistent median artery. Such variation has clinical and surgical relevance in approaching carpal tunnel syndrome and other clinical disorders in the wrist.

6.
Anat Sci Int ; 95(3): 374-380, 2020 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-32062763

RESUMO

Hearing or/and balance impairments may be caused by disorders of the labyrinthine artery (LA) and their branches. Most findings regarding the LA anatomy have been acquired through investigation of the cerebellopontine angle (CPA) in animal or adult human specimens. Eighty-eight CPAs and LAs of human fetuses were investigated using angio-techniques and microdissections. We found 15 intricate forms of distribution of LA. The LA usually originated from the extra-meatus loop in the anterior inferior cerebellar artery (AICA). The distribution of its terminal branches was 53.42% uni-arterial, 44.31% bi-arterial, and 2.27% tri-arterial systems. In the uni-arterial system, the LA described an anterior superior path to the cochlear nerve (CN) and originated its terminal branches in the gap between CN and the inferior part of the vestibular nerve. In the bi-arterial system, the anterior LA was located anterior and superior to the CN while the posterior LA appeared posterosuperior to the superior part of the vestibular nerve. In the tri-arterial system, the terminal branches originated directly from the AICA loop. Our results provide anatomical support to explain how compressions in the LA branches inside the internal acoustic meatus, as evoked by Schwannomas in the VII and VIII nerves, can lead to hearing and balance loss. The zone of the posterior vestibular nerve appeared to be a "safe area" for invasive procedures in these specimens.


Assuntos
Artérias/anatomia & histologia , Artérias/embriologia , Orelha Interna/irrigação sanguínea , Orelha Interna/embriologia , Feto/anatomia & histologia , Topografia Médica , Humanos
7.
Coluna/Columna ; 22(4): e272760, 2023. tab, graf, il. color
Artigo em Inglês | LILACS | ID: biblio-1520800

RESUMO

ABSTRACT: Objective: The present study aims to dissect and identify the Barkow ligament (LB) in fetal specimens and describe its anatomical characteristics to contribute to its knowledge in the pediatric population and the clinical and surgical application of conditions associated with the Craniovertebral Junction (CVJ). ). Methods: This work evaluated 19 human fetuses aged 28-38 weeks. Of these, six specimens constituted the final sample and were studied through detailed dissections using coronal sections in an anterior approach up to the region described by the LB. Results: In all specimens, a thin fibrous band was found, horizontal and anterior to the axis tooth, with bilateral fixation on the occipital condyles, corroborating the results found for describing LB in adults. Conclusion: The LB is a congenital ligament that resists the extension of the atlantooccipital joint and may play a role in the stability of the CVJ. Level of Evidence III; Diagnostic Study.


RESUMO: Objetivo: O presente estudo tem como objetivo dissecar e identificar o ligamento de Barkow (LB) em espécimes fetais, e descrever suas caraterísticas anatômicas visando contribuir para o seu conhecimento em população pediátrica e na aplicação clínica e cirúrgica das condições associadas à Junção Craniovertebral (JCV). Métodos: Esse trabalho avaliou 19 fetos humanos de 28-38 semanas de vida. Destes, 6 espécimes constituíram a amostra final e foram estudados através de dissecções minuciosas utilizando secções coronais, em uma abordagem anterior, até a região de descrição do LB. Resultados: Em todos os espécimes foi encontrada uma delgada banda fibrosa, de disposição horizontal e anterior ao dente do áxis, com fixação bilateral nos côndilos occipitais, corroborando com os resultados encontrados para a descrição do LB em adultos. Conclusão: O LB é um ligamento congênito, que resiste a extensão da articulação atlantoccipital, e que pode ter papel na estabilidade da JCV. Nível de Evidência III; Estudo diagnóstico.


RESUMEN: Objetivo: El presente estudio tiene como objetivo diseccionar e identificar el ligamento de Barkow (LB) en especímenes fetales, y describir sus características anatómicas con el fin de contribuir a su conocimiento en la población pediátrica y en la aplicación clínica y quirúrgica de las condiciones asociadas a la unión craneovertebral. (UCV).). Métodos: Este trabajo evaluó 19 fetos humanos de entre 28 y 38 semanas. De estos, 6 ejemplares constituyeron la muestra final y fueron estudiados mediante disecciones detalladas mediante cortes coronales, en abordaje anterior, hasta la región descrita por el LB. Resultados: En todos los ejemplares se encontró una delgada banda fibrosa, horizontal y anterior al diente axis, con fijación bilateral en los cóndilos occipitales, corroborando los resultados encontrados para la descripción de LB en adultos. Conclusión: El LB es un ligamento congénito, que resiste la extensión de la articulación atlantooccipital, y que puede desempeñar un papel en la estabilidad de la UCV. Nivel de Evidencia III; Estudio Diagnóstico.


Assuntos
Humanos , Ortopedia , Coluna Vertebral
8.
Acta Ortop Bras ; 25(2): 89-92, 2017.
Artigo em Inglês | MEDLINE | ID: mdl-28642658

RESUMO

OBJECTIVE: To verify the incidence and characterize morphologically the anterolateral ligament of the knee (ALL) in cadaveric samples of the collection of the Laboratory of Anatomy of the Department of Morphology of the Universidade Federal do Espírito Santo. METHODS: Dissections and cross sections were performed for mesoscopic analysis of the anterolateral region of 15 knees preserved in 4% formalin solution in order to identify the ALL. RESULTS: After dissection of the skin and subcutaneous tissue of the knee anterolateral region, it was possible to identify the iliotibial tract (ITT), the patellar ligament and the femoral biceps tendon. The ITT was removed from the Gerdy tubercle and the following structures were visualized: knee joint capsule, fibular collateral ligament and popliteal tendon. However, the ALL was not identified in any of the samples. CONCLUSIONS: The ALL could not be identified in any of the specimens studied, either through dissection or mesoscopic analysis. Level of Evidence III, Diagnosis Studies - Investigation of an Exam for Diagnosis.


OBJETIVO: Verificar a incidência e possivelmente caracterizar morfologicamente o ligamento anterolateral do joelho (LAL) em amostras cadavéricas do acervo do Laboratório de Anatomia do Departamento de Morfologia da Universidade Federal do Espírito Santo. MÉTODOS: Foram realizadas dissecações e secções transversais para análise mesoscópica da região anterolateral de 15 joelhos conservados em solução de formalina a 4% a fim de identificar o LAL. RESULTADOS: Após a dissecação da pele e da tela subcutânea da região anterolateral dos joelhos foi possível identificar o trato iliotibial (TIT), o ligamento patelar e o tendão do músculo bíceps femoral. Após a desinserção do TIT no tubérculo de Gerdy as seguintes estruturas foram visualizadas: cápsula articular do joelho, o ligamento colateral fibular e o tendão do músculo poplíteo. Entretanto, o LAL não foi identificado em nenhuma das amostras. CONCLUSÕES: O LAL não pôde ser identificado em nenhum dos espécimes estudados, seja através da dissecação ou da análise mesoscópica. Nível de Evidência III, Estudos Diagnósticos - Investigação de um Exame para Diagnóstico.

9.
Autops. Case Rep ; 11: e2020239, 2021. graf
Artigo em Inglês | LILACS | ID: biblio-1153181

RESUMO

The gluteal region contains important neurovascular and muscular structures with diverse clinical and surgical implications. This paper aims to describe and discuss the clinical importance of a unique variation involving not only the piriformis, gluteus medius, gluteus minimus, obturator internus, and superior gemellus muscles, but also the superior gluteal neurovascular bundle, and sciatic nerve. A routine dissection of a right hemipelvis and its gluteal region of a male cadaver fixed in 10% formalin was performed. During dissection, it was observed a rare presentation of the absence of the piriformis muscle, associated with a tendon fusion between gluteus and obturator internus, and a fusion between gluteus minimus and superior gemellus muscles, along with an unusual topography with the sciatic nerve, which passed through these group of fused muscles. This rare variation stands out with clinical manifestations that are not fully established. Knowing this anatomy is essential to avoid surgical iatrogeny.


Assuntos
Humanos , Masculino , Adulto , Nádegas/patologia , Síndrome do Músculo Piriforme/complicações , Variação Anatômica , Nervo Isquiático , Tendões , Dissecação , Músculos/anormalidades
10.
Autops. Case Rep ; 10(2): e2020151, Apr.-June 2020. graf
Artigo em Inglês | LILACS | ID: biblio-1131818

RESUMO

The authors describe a rare unilateral muscle variation in the thoracic wall combining the pectoralis quartus and chondro-epitrochlearis muscles. A routine dissection was performed in the upper right limb of a male adult cadaver with approximately 35-50 years of age, embalmed in formalin 10%. An accessory muscle, the pectoralis quartus, was identified and was associated with a tendon that was inserted in the medial humeral epicondyle, characteristic of the chondro-epitrochlearis muscle tendon. Such variations have significant clinical relevance to orthopedics, mastology, neural and vascular surgery, and other specialties, for surgical approaches in both the axillary and brachial regions.


Assuntos
Humanos , Masculino , Adulto , Parede Torácica/anatomia & histologia , Músculos/anatomia & histologia , Músculos/anormalidades , Autopsia , Tendões , Dissecação , Variação Anatômica
11.
Autops. Case Rep ; 10(4): e2020209, 2020. graf
Artigo em Inglês | LILACS | ID: biblio-1131865

RESUMO

The median artery is usually a transient vessel during the embryonic period. However, this artery can persist in adult life as the persistent median artery. This paper aims to describe this relevant anatomical variation for surgeons, review the literature and discuss its clinical implications. A routine dissection was performed in the upper left limb of a male adult cadaver of approximately 50-60 years of age, embalmed in formalin 10%. The persistent median artery was identified emerging as a terminal branch of the common interosseous artery with a path along the ulnar side of the median nerve. In the wrist, the persistent median artery passed through the carpal tunnel, deep in the transverse carpal ligament. The dissection in the palmar region revealed no anastomosis with the ulnar artery forming the superficial palmar arch. The common digital arteries emerged from the ulnar artery and the persistent median artery. Such variation has clinical and surgical relevance in approaching carpal tunnel syndrome and other clinical disorders in the wrist.


Assuntos
Humanos , Masculino , Pessoa de Meia-Idade , Síndrome do Túnel Carpal , Extremidade Superior/anatomia & histologia , Dissecação , Variação Biológica Individual , Síndromes de Compressão Nervosa
12.
Autops Case Rep ; 3(3): 5-9, 2013.
Artigo em Inglês | MEDLINE | ID: mdl-31528613

RESUMO

Variations in leg muscle are uncommon. Literature on this subject is scarce, but when those variations are reported they may cause alterations in joint mechanics or cause some discomfort in the leg and foot. The accessory soleus muscle (ASM) is considered an unusual anatomical variation, with an incidence of 0.5-6.0% in the population through studies in cadavers. During routine preparation of study material in the dissection room of the anatomy laboratory of the Escola Superior de Ciências da Santa Casa de Misericórdia de Vitória/ES - Brazil, an ASM was found in the right inferior limb of a male cadaver fixed in 10% formalin. This supernumerary muscle was 3 cm wide, 9 cm long and 1 cm thick in its most voluminous part, in typical penniform fibers arrangement. It was located in the posteromedial region of the ankle, anterior to the Achilles tendon and posterior to the deep muscles of the leg compartment. Its anterior face covered the tibial nerve and the posterior tibial vessels, while its lower half was covered by the flexor retinaculum into the tarsal tunnel. Reports in the literature show possible compression of a neurovascular bundle because of its intimal position within the tarsal tunnel, which could result in ischemic compartment syndrome.

13.
Acta ortop. bras ; 25(2): 89-92, Mar.-Apr. 2017. graf
Artigo em Inglês | LILACS | ID: biblio-837744

RESUMO

ABSTRACT Objective: To verify the incidence and characterize morphologically the anterolateral ligament of the knee (ALL) in cadaveric samples of the collection of the Laboratory of Anatomy of the Department of Morphology of the Universidade Federal do Espírito Santo. Methods: Dissections and cross sections were performed for mesoscopic analysis of the anterolateral region of 15 knees preserved in 4% formalin solution in order to identify the ALL. Results: After dissection of the skin and subcutaneous tissue of the knee anterolateral region, it was possible to identify the iliotibial tract (ITT), the patellar ligament and the femoral biceps tendon. The ITT was removed from the Gerdy tubercle and the following structures were visualized: knee joint capsule, fibular collateral ligament and popliteal tendon. However, the ALL was not identified in any of the samples. Conclusions: The ALL could not be identified in any of the specimens studied, either through dissection or mesoscopic analysis. Level of Evidence III, Diagnosis Studies - Investigation of an Exam for Diagnosis.


RESUMO Objetivo: Verificar a incidência e possivelmente caracterizar morfologicamente o ligamento anterolateral do joelho (LAL) em amostras cadavéricas do acervo do Laboratório de Anatomia do Departamento de Morfologia da Universidade Federal do Espírito Santo. Métodos: Foram realizadas dissecações e secções transversais para análise mesoscópica da região anterolateral de 15 joelhos conservados em solução de formalina a 4% a fim de identificar o LAL. Resultados: Após a dissecação da pele e da tela subcutânea da região anterolateral dos joelhos foi possível identificar o trato iliotibial (TIT), o ligamento patelar e o tendão do músculo bíceps femoral. Após a desinserção do TIT no tubérculo de Gerdy as seguintes estruturas foram visualizadas: cápsula articular do joelho, o ligamento colateral fibular e o tendão do músculo poplíteo. Entretanto, o LAL não foi identificado em nenhuma das amostras. Conclusões: O LAL não pôde ser identificado em nenhum dos espécimes estudados, seja através da dissecação ou da análise mesoscópica. Nível de Evidência III, Estudos Diagnósticos - Investigação de um Exame para Diagnóstico.

14.
Coluna/Columna ; 14(2): 144-148, Apr.-June 2015. tab, ilus
Artigo em Inglês | LILACS | ID: lil-755837

RESUMO

Currently there is a growing interest in the study of intervertebral discs due to loss of manpower brought to society by low back and neck pains. These papers seek to delineate the difference between normal aging and disc degeneration, trying to understand what factor would be determining for the second condition. Thus, the morphology field was expanded and knowledge on the structure of intervertebral discs currently uses the research field of cell and molecular biology, and genetics. The results indicate that regardless of age or condition, the intervertebral disc undergoes long and extensive remodeling of its constituents, which are influenced by several factors: environmental, soluble, cell growth and extracellular matrix. In this literature review we describe the biological characteristics of the cervical and lumbar intervertebral disc with a focus on basic science of aging and degeneration, selecting the latest findings and discussions of the area, which influence future research and clinical thoughts.


Atualmente ocorre um crescente interesse no estudo dos discos intervertebrais em virtude da perda da força de trabalho que a lombalgia e a cervicalgia trazem à sociedade. Esses trabalhos buscam delinear a diferença entre envelhecimento normal e degeneração discal, tentando entender qual fator seria determinante para a segunda condição. Assim, o campo da morfologia foi ampliado e o conhecimento sobre a estrutura dos discos intervertebrais hoje utiliza investigações no campo da biologia celular, molecular e da genética. Os resultados apontam que, independentemente da idade ou condição de enfermidade, o disco intervertebral sofre extenso e longo remodelamento de seus constituintes, os quais sofrem influências de diversos fatores: ambientais, solúveis e de crescimento das células e da matriz extracelular. Nesta revisão da literatura, descrevem-se as características biológicas do disco intervertebral cervical e lombar, com foco na ciência básica do envelhecimento e degeneração, selecionando as mais recentes descobertas e discussões da área, as quais influenciam futuras pesquisas e pensamentos clínicos.


Actualmente existe un creciente interés en el estudio de los discos intervertebrales debido a la pérdida de mano de obra que el dolor del cuello y lumbar aportan a la sociedad. Estas obras tratan de delimitar la diferencia entre el envejecimiento normal y la degeneración del disco, tratando de entender qué factor sería decisivo para la segunda condición. Así, el campo de la morfología se amplió y los conocimientos sobre la estructura de los discos intervertebrales utiliza actualmente la investigación en el campo de la biología celular y molecular, además de la genética. Los resultados indican que, independientemente de su edad o estado de la enfermedad, el disco intervertebral sufre una remodelación extensa y larga de sus componentes, que son influenciados por varios factores: el ambiente, solubles y de crecimiento celular y de la matriz extracelular. En esta revisión de la literatura se describen las características biológicas del disco intervertebral cervical y lumbar, con un enfoque en la ciencia básica del envejecimiento y la degeneración, seleccionando los últimos descubrimientos y discusiones del área, que influyen en la futura investigación y pensamientos clínicos.


Assuntos
Disco Intervertebral/anatomia & histologia , Envelhecimento , Dor Lombar , Cervicalgia
15.
Biosci. j. (Online) ; 31(5): 1561-1569, sept./oct. 2015.
Artigo em Inglês | LILACS | ID: biblio-965019

RESUMO

Malnutrition remains an important public health condition by affecting mostly children. The present study aimed to examine the effects of prenatal protein undernourishment and postnatal renourishment on the metabolism of pre-adult animals. Forty-five male Wistar rats originating from different litters were used. The Nourished (N, n=15) and Undernourished (U, n=30) groups were maintained on proteic and hypoproteic diets (20% and 5% casein, respectively) from the intrauterine phase until the end of the experiment. The Renourished group (R) contained 15 animals, randomly chosen from U group, that consumed the N diet beginning on day 21 (weaning). All groups were maintained until day 60. The experimental data was acquired daily for body weight, feed and water intake, feces and urine excretion. Data analysis was made with the total results and the ratio between them. The U group animals developed uniformly sparse hair late and experienced intense sweating, features that were not observed during the experiment in the R and N animals groups. The R group had the largest weight gain and feed and water intake ratio/weight at experimental period, followed by the N group animals. The final body weight and food intake decreased gradually in the order N-R-U, but none of the other parameters showed a statistical difference between the N and R animals. Compared to groups N and R, the U group animals consumed 90% and 81% more food and water, respectively. Protein undernourishment induced metabolic dysfunction in the U group animals. The similarity in the experimental parameters of the N and R groups suggests that an early feeding correction was effective in reestablishing the organic functions of the R group animals.


A subnutrição ainda é uma condição importante na saúde pública por afetar principalmente crianças. O presente estudo tem o objetivo de avaliar os efeitos da subnutrição pré-natal e renutrição pós-natal no metabolismo de ratos jovens. Quarenta e cinco ratos Wistar machos originados de diferentes ninhadas foram utilizados. O grupo Nutrido (N, n=15) e Subnutrido (U, n=30) foram mantidos sob dieta protéica e hipoprotéica (20% e 5% de caseína, respectivamente) desde a fase intrauterina até o final do experimento. O grupo Renutrido (R) conteve 15 animais aleatoriamente selecionados do grupo U para consumir a dieta protéica a partir do dia 21 pós-natal (desmame). Todos os grupos foram mantidos até o dia 60. Os animais do grupo U desenvolveram pelos tardiamente, uniformemente escassos e sudorese intensa, fato não visto ao longo do experimento nos animais R e N. Os animais R obtiveram o maior ganho de peso, fração ingestão por peso e consumo de água por peso no período experimental, seguido pelo grupo N. O peso corporal final e a ingestão final de alimento ficaram decrescentes na ordem N-R-U, enquanto que para todos os outros parâmetros não houve diferença estatística entre o animal N e R. Comparativamente ao grupo N e R, o grupo U consumiu 90% e 81% a mais de alimento e água, respectivamente. A subnutrição proteica induziu disfunção metabólica nos animais U. A semelhança nos parâmetros experimentais entre o grupo N e R sugere que a correção precoce da alimentação foi eficaz no retorno das funções orgânicas dos animais R.


Assuntos
Deficiência de Proteína , Ratos , Ratos Wistar , Desnutrição , Fenômenos Fisiológicos da Nutrição Animal , Metabolismo
16.
Rev. med. (Säo Paulo) ; 87(2): 142-147, 2008. tab, graf
Artigo em Português | LILACS | ID: lil-506459

RESUMO

O enrijecimento arterial é um fator de risco independente para doença cardiovascular, podendo se agravar com a idade e sendo atenuado pelo exercício físico principalmente em idosos. O objetivo deste estudo foi correlacionar à capacidade física de indivíduos idososcom a Velocidade de Onda de Pulso (VOP). Para tanto, foi avaliada a complacência dos grandes vasos de pacientes do sexo masculino obtido através da medida da VOP com o aparelho COMPLIOR II. O nível de capacidade física foi obtido com o teste de esforço submáximo (teste de caminhada de 6 minutos). Nossos dados sugerem que a rigidez arterial aumenta com a idade, que esta rigidez esta intimamente ligada ao nível de aptidão cardiorrespiratória e que este pode sugestivamente influenciar na prevenção do enrijecimento arterial.


The arterial stiffness is an independent cardiovascular risk factor of aging, whichcould be measure by the Pulse Wave Velocity (PWV). The aim of this study was correlate the physical capacity of aging men to the PWV. In order to measure arterial compliance of greatvessels in aging males we used a COMPLIOR II equipment to determine PWV. Physical capacity levels were obtained by 6 minutes walking test. Our data suggest that arterial stiffnessincrease by the age, and it is intimately close to the level of cardiorespiratory fitness. The results also indicate that effects of physical capacity has some influence on the prevention of arterial stiffness.


Assuntos
Atividade Motora , Capacitância Vascular , Complacência (Medida de Distensibilidade) , Envelhecimento , Idoso
17.
Rev. med. (Säo Paulo) ; 88(2): 80-86, abr.-jun. 2009. tab, graf
Artigo em Português | LILACS | ID: lil-539093

RESUMO

O suporte parcial de peso (SPP) foi utilizado pela primeira vez em âmbitos clínicos nos anos 80. Acredita-se que essa terapia promova melhora da marcha em pacientes com seqüela de Acidente Vascular Encefálico (AVE). Investigamos a importância do treino de marcha na esteira elétrica com SPP nesses pacientes. Sete pacientes com diagnóstico clínico de hemiparesia ou hemiplegia foram submetidos aleatoriamente a um protocolo de treinamento em esteira elétrica em SPP (Experimental, n = 4), ou ao tratamento tradicional sem SPP (Controle, n = 3) por 20 sessões, para avaliar o equilíbrio. Observou-se melhora estatisticamente significante no equilíbrio avaliado pela escala de BERG no Grupo Experimental (p = 0,003). Mais estudos são necessários para elucidar os resultados obtidos...


The Body Weight Support (BWS) was used for the first time in clinical studies by the 80s. It is believed that this therapy promotes improvement of gait in patients with Stroke sequel. We investigated the importance of gait training in treadmill with BWS in those patients. Seven patient with clinical diagnosis of hemiparesis or hemiplegia were randomly submitted toa treadmill training protocol with BWS, (Experimental, n=4), or to traditional approach without BWS (Control, n=3) for 20 sessions to balance evaluation. The balance evaluation by BERG scale showed significant improves on experimental group (p = 0,003). Further investigations should be conducted in order to elucidate those data obtained...


Assuntos
Humanos , Masculino , Feminino , Adolescente , Adulto , Pessoa de Meia-Idade , Idoso de 80 Anos ou mais , Acidente Vascular Cerebral/reabilitação , Equilíbrio Postural , Marcha , Paresia , Suporte de Carga
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